Jurnal Farmasi Sains dan Komunitas (JFSK)
Vol 14, No 2 (2017)

VIRTUAL SCREENING CAMPAIGNS ON ISOFLAVONES TO DISCOVER POTENT CYCLOOXYGENASE-2 INHIBITORS

Enade Perdana Istyastono (Faculty of Pharmacy, Sanata Dharma University, Yogyakarta)



Article Info

Publish Date
30 Nov 2017

Abstract

By employing recently published structure-based virtual screening (SBVS) to identify potent cyclooxygenase-2 (COX-2) inhibitors, all isoflavones collected by ZINC15 database were virtually screened. There were 3371 isoflavones in ZINC15 database and 1356 compounds out of them met the Lipinskis rule of 5. Notably, only 3 isoflavones out of those 1356 compounds were identified as potent COX-2 inhibitors.

Copyrights © 2017






Journal Info

Abbrev

JFSK

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical ...