Journal of Maternal and Child Health
Vol 5, No 4 (2020)

Premature Rupture of Membrane Outcome Determinants in Reproductive Age Women

Zakirah, Sarah Chairani (Unknown)
Eyanoer, Putri Chairani (Unknown)
Azali, Chairul Nurdin (Unknown)
Wiweko, Budi (Unknown)

Article Info

Publish Date
23 Oct 2020


Background:  Premature Rupture of Membrane (PROM) may cause maternal and neonatal mor­bi­dity and mortality. This study aimed to in­ves­ti­ga­te the risk factors related to PROM in pregnant wo­men below <35 years old.Subjects and Method: This cross-sectional stu­dy was conducted in Kertha Usada General Hos­­­pital, North Bali, Indonesia. We collected 224 repoductive women using consecutive sampling. The dependent variable was premature rupture of membrane. The inde­pen­­dent variables were gra­vidity status, ges­ta­tio­nal age, body mass index (BMI), history of cae­sa­rean section, miscarriage, infection, and anemia. Data of infection was obtained from examination, such as neutro­phil, lymphocyte, platelet, neutrophil-to-lympho­cyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). We also obtained Hb, MCV, and MCH as laboratory parameter of ane­mia. The data were analyzed by a multiple logistic regress­ion.Results: Multigravida (or= 0.04; 95% CI= 0.01 to 0.27; p= 0.001) and MCH >34 pg (OR= 0.10; 95% CI= 0.01 to 0.86; p= 0.036) decreased the risk of premature of rupture membrane in women of reproductive age.Conclusion: Multigravida and MCH >34 pg decrease the risk of premature of rupture mem­brane in women of reproductive age.Keywords: premature rupture membraneCorrespondence: Putri Chairani Eyanoer. Department Community and Preventive Medicine, Faculty of Medicine, Uni­­versitas Sumatera Utara, Medan, Indonesia. Email: Mobile: +62-813 7023-2513Journal of Maternal and Child Health (2020), 5(4): 576-586

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Medicine & Pharmacology Public Health


Journal of Maternal and Child Health (JMCH) is an electronic, open-access, double-blind and peer-reviewed international journal, focusing on maternal and child health. The journal began its publication on July 11, 2015, and is published four times yearly. JMCH aims to improve the policy, program, ...