journal of Basic Medical Veterinary
Vol. 9 No. 1 (2020): Journal of Basic Medical Veterinary, June 2020

UJI PENETAPAN STABILITAS RETENTION TIME Megestrole acetate DALAM ELUENT MOBILE PHASE MENGGUNAKAN HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

Siti Chusnul Cholifah (Fakultas Kedokteran Hewan Universitas Airlangga)
Mochamad Lazuardi (Fakultas Kedokteran Hewan Universitas Airlangga)
Dadik Rahardjo (Fakultas Kedokteran Hewan Universitas Airlangga)
Lilik Maslachah (Fakultas Kedokteran Hewan Universitas Airlangga)
Mohammad Sukmanadi (Fakultas Kedokteran Hewan Universitas Airlangga)
Rochmah Kurnijasanti (Fakultas Kedokteran Hewan Universitas Airlangga)



Article Info

Publish Date
01 Aug 2020

Abstract

The aim of this research was to determine the level of stability of Megestrole acetate-retention time in storage period for six, eight and 12 hours using High Performance Liquid Chromatography (HPLC). The research method used posttest-only control group design by using three treatments and six repetitions. The three repetitions consist into six hours, eight hours and 12 hours. The data were obtained analyzed by Summery Independent T-Test with SPSS 24 for windows. The result showed six hours retention time of Megestrole acetate is stable and eight hours treatment and 12 hours treatment are not stable there is one unstable point of 12 hours treatment that indicates the substance is break down. Based on those result, it could be concluded that the storage time of Megestrole acetate in Eluent Mobile Phase began to show unstable at eight hours of storage.

Copyrights © 2020






Journal Info

Abbrev

JBMV

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Description

This journal published original articles, review articles, and case studies in Indonesian or English, in the scope of JBMV has a broad coverage of relevant topics across veterinary basic medical sciences which includes: preclinical and paraclinical disciplines like Anatomy, Physiology, Biochemistry, ...