Jurnal Medik Veteriner
Vol. 4 No. 2 (2021): October

Necrosis Description of Mice Liver Induced with Monosodium Glutamate and Methanol Robusta Coffee Bean Extract (Coffea canephora)

Tisya Yumn Al-Zuhroh (Bachelor of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga)
Kuncoro Puguh Santoso (Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga)
Maya Nurwartanti Yunita (Department of Pathology, Faculty of Veterinary Medicine, Universitas Airlangga)
Nove Hidajati (Department of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga)
Ratih Novita Praja (Department of Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga)

Article Info

Publish Date
31 Oct 2021

Abstract

This study aimed to analyze the effect of methanol robusta coffee bean extract (Coffea canephora) on liver histopathological description in mice induced with monosodium glutamate (MSG). This study was used 20 male mice for 5 treatment groups: K + (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg and RCE 0.1 mg), P2 (MSG 0.12 mg and RCE 0.2 mg), and P3 (MSG 0.12 mg and RCE 0.4 mg) per orally for 42 days. Liver histological scores were analyzed using Kruskal Wallis test. The results of Kruskal Wallis test scored p=0,391 which indicates that the data is not significant (p>0.05). In the control and treatment groups there were no significant. In conclusion, the giving methanol robusta coffee bean extract did not show a decrease in hepatosite damage that was different from the negative control treatment group.

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Journal Info
Jurnal Medik Veteriner
Website

Abbrev

JMV

Publisher

Universitas Airlangga

Subject

Biochemistry, Genetics & Molecular Biology Veterinary

Description

urnal Medik Veteriner (JMV) publishes high quality and novelty papers focusing on Veterinary and Animal Science. The fields of study are anatomy, pathology, basic medicine, veterinary public health, microbiology, veterinary reproduction, parasitology, animal husbandry and animal welfare. Food ...