Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Vol 53, No 4 (2021)

Treatment of functioning pituitary macroadenoma with endoscopic transsphenoidal surgery: a case report

Agusni Agusni (Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Willy Adhimarta (Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Andi Asadul Islam (Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Djoko Widodo (Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Nasrullah Nasrullah (Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Andi Ihwan (Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Prihantono Prihantono (Department of Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar)
Muhammad Faruk (Hasanuddin University, Makassar, Indonesia)



Article Info

Publish Date
11 Dec 2021

Abstract

Pituitary macroadenomas are benign tumors in the pituitary gland measuring more than 1 cm in diameter. Pituitary adenomas account for 8 to 10% of all intracranial tumors and occur primarily in the anterior pituitary lobe and rarely in the posterior lobe. Most pituitary macroadenomas are non-functioning tumors, which show clinical symptoms due to tumor pressure and do not increase hormonal activity. In this case, a 40 y.o. woman was diagnosed with a pituitary macroadenoma after showing clinical symptoms of a functioning tumor, namely acromegaly, prognathism, and large, beefy hands and feet, for the past 4 years. Complaints were accompanied by amenorrhea, intermittent cephalgia, and hemianopsia in the right eye. Blood laboratory tests revealed increased levels of prolactin and growth hormone, while the results of computed tomography (CT) scans and magnetic resonance imaging (MRI) of the head indicate the presence of a pituitary macroadenoma. Endoscopic transsphenoidal surgery, a minimally invasive procedure, was performed with minimal complications.

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Journal Info

Abbrev

bik

Publisher

Subject

Immunology & microbiology Neuroscience

Description

Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality ...