<![CDATA[Mosquitoes are disturbing ectoparasites that harm health, humans, animals and the environment. This is because of its ability as a vector of various diseases. One of the controls that can be done is by using biological insecticides, the Calontopis gigantea plant or the snake plant on the bark which is considered capable of eradicating mosquitoes. The purpose of this study was to determine the effect of the dose of the extract of the leaf stem bark on the death of mosquito larvae. The population in this study were Aedes aegypti mosquito larvae with a total of 450 mosquito larvae and snake plant stem parts. The study was conducted in the Pharmacy laboratory of UMI which is an experimental study. The results showed that there was no effect of mosquito larvae death on mosquito larvae death. At a dose of 0.1 ml of the extract of the plant bark in 100 ml of habitat water the average time of death is 17.4 minutes, a dose of 0.5 ml with an average time of 45 minutes, a dose of 1.0 ml with an average death time of 13.2 minutes., A dose of 1.0 ml with an average death time of 30 minutes, then at a dose of 2.0ml with an average death time of 29.4 minutes. Based on the results of data analysis shows that the value of p = 0.63> α = 0.05. Then Ha is rejected, meaning that the hypothesis stating there is an effect of extract dose on mosquito larvae death is rejected. The conclusion is that there is no effect of the extract of the plant stem bark on mosquito larvae death. It is recommended to use the right amount of dose to affect the Aedes aegypti mosquito larvae.]]>
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