Asian Journal of Aquatic Sciences
Vol 4 No 3 (2021): December

ACUTE TOXICITY WATER EXTRACT OF Meretrix meretrix Linnaeus IN VIVO ON SPRAGUE DAWLEY RATS

Azwin Apriandi (Universitas Maritim Raja Ali Haji)
Kustiariyah Tarman (Aquatic Product Technology of Department, Bogor Agricultural University)
Purwantiningsih Sugita (Chemistry of Department, Bogor Agricultural University)

Article Info

Publish Date
21 Dec 2021

Abstract

Meretrix meretrix empirically has been widely believed by the public to a wide variety of health benefits. It is necessary to do an analysis of the level of toxicity of Meretrix meretrix extract. The experiment was carried out extraction sample with water (1;4) (w/v), analysis of acute toxicity Meretrix meretrix extract with the OECD method 403:2009. Based on the results of water extract of Meretrix meretrix no effect on physical observations of test animals with LD50> 15 g/kg BW. Histopathological observation on the liver and kidneys, there is necrosis of the liver cells and some cell degeneration in the kidneys, but on the whole network under normal conditions appropriate control group

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Journal Info
Asian Journal of Aquatic Sciences
Website

Abbrev

ajoas

Publisher

Universitas Riau

Subject

Agriculture, Biological Sciences & Forestry

Description

Asian Journal Of Aquatic Sciences is a journal publishes scientific articles from research by lecturers and other researchers in the waters sector. Focusing on aspects of aquatic ecology for the use of this habitat as an ecosystem for producing food (fisheries and agriculture) and its function for ...