Acta Biochimica Indonesiana
Vol. 4 No. 2 (2021): Acta Biochimica Indonesiana

The relationship between vitamin E and C intake with total activity of erythrocytes and breast milk superoxide dismutase in lactating mothers

Ninik Mudjihartini (Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia)
Diyah Eka Andayani (Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia)
Sheira Taflah Putri Handana (Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia)



Article Info

Publish Date
15 Dec 2021

Abstract

Background: Human milk contains many components, one of them is superoxide dismutase (SOD). Vitamin E and C, together with SOD, can prevent oxidative stress. Objective: This study investigated the correlation between vitamin E and vitamin C intake, with total SOD activity, in erythrocyte and breast milk among lactating mothers in Jakarta, Indonesia. Methods: Sixty lactating mothers aged 20–40 years were recruited in 1–6 months postpartum in Grogol Petamburan and the Cilincing Public Health Centre from March 2019 until April 2019. Vitamins E and C dietary intake were collected using a semi-quantitative food frequency questionnaire. SOD total activity of erythrocyte and breast milk was measured using the Ransod kit 125. Results: The median value of vitamin E intake was 6.50 mg/day, showing 91.7% of patients do not meet recommended daily intake (RDA) (19 gram/day), and the median of vitamin C intake was 120.05 mg/day with 70% participants fulfilling RDA. SOD total activity in erythrocyte and breastmilk showed a median value of 423.73 U/mL and 58.34 U/mL, respectively. The correlation between vitamin E intake with total SOD activity in erythrocyte (r = 0.143 p > 0,05) and breast milk (r = 0.041, p > 0,05) was not significant. Vitamin C intake was also not significantly correlated with SOD total activity in the erythrocyte. Conclusion: There is no significant correlation between vitamin E and vitamin C intake with the total activity of SOD of erythrocyte and breast milk in lactating mothers.

Copyrights © 2021






Journal Info

Abbrev

actabioina

Publisher

Subject

Biochemistry, Genetics & Molecular Biology

Description

Acta Biochimica Indonesiana (ActaBiolna) is a peer-reviewed and open-access journal that disseminates original research articles and review articles covering diverse topics in Biochemistry and Molecular Biology. The journal is published biannually by Indonesian Society for Biochemistry and Molecular ...