Eureka Herba Indonesia
Vol. 2 No. 1 (2021): Eureka Herba Indonesia

Potential Combination of Tinospora crispa, Andrographis paniculata, Cinnamomum burmanii, Syzygium polyanthum, and Momordica charantia Extracts Against Intake of Glucose in Muscle Rats-Induced Diabetes Mellitus

Rachmat Hidayat (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Patricia Wulandari (Cattleya Mental Health Center, Palembang, Indonesia)



Article Info

Publish Date
08 Mar 2021

Abstract

Diabetes mellitus is a chronic condition that disturbs the body's blood sugar regulation. This disorder is characterized by a decrease in the ability of body cells to intake glucose into cells. Due to the failure of cells in glucose intake, glucose buildup occurs in the extracellular, namely in the plasma. These medicinal plants contain quite varied secondary metabolites, and these plants are rich in flavonoids, alkaloids, terpenes, and glycosides. The content of these secondary metabolite compounds is believed to be rich in antioxidant effects so that it has the effect of being able to suppress various oxidative stress conditions that cause damage to various organs due to blood sugar dysregulation. The effect of Tinospora crispa, Andrographis paniculata, Cinnamomum burmanii, Syzygium polyanthum and Momordica charantia extract on blood sugar levels and GLUT4 protein expression in muscle tissue shows the potential of the test extract's ability to improve blood glucose intake to cells so as to maintain blood sugar regulation.

Copyrights © 2021






Journal Info

Abbrev

EHI

Publisher

Subject

Medicine & Pharmacology

Description

Eureka Herba Indonesia (EHI) is peer review scientific journal that focused on reserach in exploration potential Herba of Indonesia for enhancing healthy. EHI focused on : 1. Medicinal Plants. 2. Efficacy of Herba Study. 3. Safety of Herba Study. 4. Animals that potential for developing as healthy ...