Indonesian Journal of Cancer Chemoprevention
Vol 2, No 1 (2011)

Phytochemical Screening and Toxicological Evaluation Using Brine Shrimp Lethality Test (BSLT) of Some Fractions of Prasman Leaves (Eupatorium triplinerve V) Extract

Kumala, Shirly ( Faculty of Pharmacy, Pancasila University)
Sapitri, Dwi Windi ( Faculty of Pharmacy, Pancasila University)



Article Info

Publish Date
31 Jul 2012

Abstract

Prasman leaves (Eupatororium triplinerve V) was well documented to have anti cancer benefit in Indonesian traditional medicine history. However, there were noscientific studies including toxicological assessment on the planextract.The purpose of this study was to investigate thetoxicological effect of some fractions of Prasman leavesmethanol extract. Phytochemical screening by the Farnsworth method on powder and some fraction of the methanol extractwere conducted followed by toxicitytest using the “Brine Shrimp Lethality” test (BSLT) method. In the current study results, the phytochemical screening showed the presence of flavonoid, saponin, coumarin, tannin, steroidandvolatileoil.LC50ofthen-hexanefraction238.660g/mL,ethylacetatefraction 24.420g/mL,andn3butanol64.100g/mL.

Copyrights © 2011






Journal Info

Abbrev

ijcc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Indonesian Journal of Cancer Chemoprevention (IJCC) is an open access, peer-reviewed, triannual journal devoted to publishing articles on Cancer Chemoprevention including Experimental and Clinical Pharmacology, especially concerning Anti-Oxidants, Anti-Aging, Anti-Inflammation, Anti-Angiogenesis, ...