This study aims to analyze the effectiveness of laboratory used in practices biology field at Two Senior high school, called SMA in Manokwari regency. This study is a qualitative-descriptive. The data collected by observation sheets, or quistionnaries. that answered by two teachers and six students. The result showed that SMA Negeri 1 Prafi effectivelly in used laboratory for doing practices or effectively categorized by 74,72% and SMA Katolik Villanova reached up and average 67.56% means to support the laboratory Experient or categorized as effective. While obstacles of the Two school still high reached up 80%, while the percentage of the standardized laboratory equipments are familier spread from 49%-51%.
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