Jurnal Respirasi (JR)
Vol. 8 No. 2 (2022): May 2022

Risk Factors and Challenging Management of Lung Adenocarcinoma in Young Adult Women: Case Series

Ida Ayu Jasminarti Dwi Kusumawardani (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali.)
Luh Komang Ayu Widhiaty Karang (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali.)
Ni Wayan Candrawati (Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali.)
Herman Saputra (Department of Anatomical Pathology, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali.)
Ni Putu Sriwidyani (Department of Anatomical Pathology, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali.)
Nornazirah Binti Azizan (Department of Pathology and Microbiology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Sabah, Malaysia.)



Article Info

Publish Date
31 May 2022

Abstract

Introduction: Lung cancer found in young age is relatively rare with a percentage of cases only 1.4% of overall lung cancer cases in the world. Case: We reported two cases of lung adenocarcinoma in young women aged less than 30. The first case was lung adenosquamous carcinoma in a 28-year-old woman, a passive smoker, who had a family history of cancer. She had the mutation of epidermal growth factor receptor (EGFR) exon 19 deletion and received 1st generation of tyrosine kinase inhibitor. Since the patient was diagnosed at advanced stage with poor performance status, she died within 2 months after being diagnosed. The second case was lung adenocarcinoma in a 23-year-old woman. The patient was a passive smoker and had a history of cancer in the family. She was diagnosed at an advanced stage but with good performance status. The patient underwent chemotherapy with Pemetrexed-Platinum in 6 cycles and 15 cycles of radiotherapy. Conclusion: Lung cancer at a young age is more common in non-smoking female with the histopathology type adenocarcinoma. Non-specific early symptoms become a problem in the early enforcement of lung cancer at a young age. Many cancer-related issues occur in young cancer patient such as premature death, increased dependence on parents, difficulty in school and work due to medication, and reproductive disturbance.

Copyrights © 2022






Journal Info

Abbrev

JR

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in ...