Asian Journal of Health Research
Vol. 1 No. 2 (2022): Volume 1 No 2 (August) 2022

Case Report: Secondary Amenorrhea with Hyperprolactinemia due to Pituitary Macroadenoma

Annissa Febriani (Department of Obstetrics and Gynecology, Faculty of Medicine, University of Brawijaya/ Saiful Anwar General Hospital, Malang, East Java, Indonesia)
Donny Wisnu Wardhana (Department of Neurosurgeon, Faculty of Medicine, University of Brawijaya East Java, Malang, East Java, 65145, Indonesia)
Nugrahanti Prasetyorini (Department of Obstetrics and Gynecology, Faculty of Medicine, University of Brawijaya/ Saiful Anwar General Hospital, Malang, East Java, Indonesia)
Pande Made Dwijayasa (Department of Obstetrics and Gynecology, Faculty of Medicine, University of Brawijaya/ Saiful Anwar General Hospital, Malang, East Java, Indonesia)



Article Info

Publish Date
27 Jul 2022

Abstract

Introduction: Secondary amenorrhea has a broad etiology, so each case must be studied in depth. One of the causes of secondary amenorrhea is a state of hyperprolactinemia caused by a mass in the anterior pituitary. Pituitary macroadenoma patients may be asymptomatic or have a hormone imbalance or mass impact symptoms. Tumors in asymptomatic patients might be identified during a routine head imaging examination for unrelated medical issues. Case Presentation: A 24-year-old unmarried woman with complaints of headache, blurred vision, and worsening for one year ago. The patient complained of not having menstruation in the past five years ago, with a history of previous normal menstruation. On physical examination, found breast and pubic Tanner stage 5. On laboratory examination, it was found FSH (2.21), Oestradiol (20.23), and Prolactin (1365.47). On an MRI of the head examination on April 14, 2021, a solid intrasellar mass of suspected pituitary macroadenoma was found with a size of ± 1.3 cm x 1.4 cm x 1.6 cm. Conclusion: Secondary amenorrhea caused by hyperprolactinemia due to pituitary macroadenoma is a rare case (40%). First-line therapy for prolactinomas is dopamine agonist administration because most pituitary macroadenomas respond to dopamine agonists.

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Journal Info

Abbrev

a-jhr

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Asian Journal of Health Research (AJHR) is an open access journal published by Ikatan Dokter Indonesia Wilayah Jawa Timur and launched in 2022. This journal is peer reviewed publishing to communicate high quality research, general articles, and all fundamental research/ clinical studies relevant to ...