Journal of Pain, Vertigo and Headache
Vol. 1 No. 2 (2020): September

PARACETAMOL, MIGRAINE, AND MEDICATION OVERUSE HEADACHE (MOH)

Hanik Hidayati (Neurology Department, Medical Faculty, Airlangga University, Dr. Soetomo General Hospital, Surabaya, Indonesia)
Anung Kustriyani (Siti Aisyah Clinic, Surabaya, Indonesia)

Article Info

Publish Date
01 Sep 2020

Abstract

Paracetamol is a nonopioid synthesized p-aminophenol derivative that used as an antipyretic and an analgesic. Paracetamol is an over the counter medicine. 15.6% of migraine patients took paracetamol for headache relief. In migraine, paracetamol is used long term. This triggers paracetamol to cause Medication Overuse Headache (MOH). Animal studies associated paracetamol induced MOH based on pathophysiology migrenes. There three mechanism underline MOH include effect to korteks cerebral, effect to system trigeminal nociception, and effect to central modulating systems.

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Journal Info
Journal of Pain, Vertigo and Headache
Website

Abbrev

jphv

Publisher

Universitas Brawijaya

Subject

Neuroscience

Description

JPHV - Journal of Pain, Headache and Vertigo is a peer-reviewed and open access journal that focuses on promoting pain, headache and vertigo. This journal publishes original articles, reviews, and also interesting case reports. JPHV - Journal of Pain, Headache and Vertigo is an international ...