Trends in Infection and Global Health
Vol 1, No 2 (2021): December 2021

Irrational use of azithromycin in typhoid endemic areas: A challenge on multidrug-resistant typhoid treatment

Irfan Ullah (Kabir Medical College, Gandhara University, Peshawar, Pakistan)
Kiran Shafiq Khan (Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan)
Qasim Mehmood (King Edward Medical University, Lahore, Pakistan)
Muhammad Junaid Tahir (Ameer-ud-Din Medical College, Affiliated with University of Health and Sciences, Lahore, Pakistan
Lahore General Hospital, Lahore 54000, Pakistan)

Muhammad Irfan Malik (Ameer-ud-Din Medical College, Affiliated with University of Health and Sciences, Lahore, Pakistan
Lahore General Hospital, Lahore 54000, Pakistan
European Respiratory Society, Lausanne, Switzerland)

Ali Ahmed (School of Pharmacy, Monash University, Bandar Sunway, Malaysia)
Muhammad Usman Munir (College of Pharmacy, Jouf University, Sakaka, Aljouf, 72388, Saudi Arabia)



Article Info

Publish Date
11 Dec 2021

Abstract

Typhoid is a food-borne fatal disease caused by Salmonella typhi. It causes inflammation of the intestine, resulting in diarrhoea, fever, headache, cough, and muscle pain. Improved hygiene has resulted in a marked decline in typhoid fever cases in many developed countries. However, significant typhoid cases emerge in low and middle-income countries annually, including Pakistan. Typhoid fever accounts for a larger percentage of acute febrile illnesses in Pakistan. Azithromycin is the only effective drug used in multidrug-resistant typhoid. The emergence of drug resistance typhoid has been of more significant concern in recent years due to its irrational use of azithromycin. It is considered the last antibiotic to eradicate multidrug-resistant typhoid fever from Pakistan. In this article, we express our concern of the irrational use of azithromycin in Pakistan and its effect on typhoid in the country.

Copyrights © 2021






Journal Info

Abbrev

TIGH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology Maternal and child health Clinical tropical ...