PHARMACON
Vol. 12 No. 3 (2023): PHARMACON

The Toxicity Test of The Extract of Pepper Elder (Peperomia pellucida L. Kunth) Using Brine Shrimp Lethality Test (BSLT).

Angelica Togelang (Universitas Sam Ratulangi)
Herni E.I Simbala (Universitas Sam Ratulangi)
Surya Sumantri Abdullah (Universitas Sam Ratulangi)



Article Info

Publish Date
22 Aug 2023

Abstract

Pepper Elder (Peperomia pellucida L. Kunth) is one of the herbal plants that has the potential as an anticancer. Pepper Elder is a weed plant that grows wild in wet and humid environments but is rarely cultivated. Research on the Pepper Elder plant aims to determine the metabolite compounds contained in the plant, its potential as an anticancer, and the LC50 value. The research was conducted using an experimental method with the Brine Shrimp Lethality Test (BSLT) method. Extraction was carried out by maceration method to extract secondary metabolites. Through screening tests it is known that Pepper Elder contains alkaloids, flavonoids, tannins, saponins, and steroids. Tests were carried out with Artemia saline L. larvae at concentrations of 1000 µg/mL, 100 µg/mL, 10 µg/mL, 1 µg/mL with the potency obtained at the toxic level and LC50 value is 40.947 µg/mL.

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Journal Info

Abbrev

pharmacon

Publisher

Subject

Medicine & Pharmacology

Description

Pharmacon is the journal published by Pharmacy Study Program, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Indonesia (P-ISSN: 2302-2493 E-ISSN: 2721-4923). Pharmacon was established in 2012 and published four times a year. Pharmacon is an open access journal and has been ...