INDONESIAN JOURNAL OF PHARMACY
Vol 19 No 3, 2008

Chemical composition and antibacterial properties of the essential oil of Pogostemon cablin

Aisyah, Yuliani ( Department of Agricultural Technology, Faculty of Agriculture, Unsyiah Banda Aceh)
Hastuti, Pudji ( Faculty of Agricultural Technology, Universitas Gadjah Mada Yogyakarta)
Sastrohamidjojo, Hardjono ( Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada Yogyakarta)
Hidayat, Chusnul ( Faculty of Agricultural Technology, Universitas Gadjah Mada Yogyakarta)



Article Info

Publish Date
01 Jul 2008

Abstract

The aim of this research were to evaluate the chemical compositions and antibacterial activities of patchouli. The identification of patchouli oil was carried out by using gas chromatography-mass spectrophotometer, fractionation of patchouli oil was done by vacuum fractionational distillation method. The gas chromatography mass spectra showed that the patchouli oil consisted of 15 components. It was found that the five major components were patchouli alcohol, Δ-guaiene, α-guaiene, seychellene and α-patchoulene. Patchouli oil and high boiling point fraction exhibited antibacterial activity, while the low boiling point fractions did not show the antibacterial properties. The antibacterial properties found to be more effective for the Gram-positive bacteria than that the Gram-negative bacteria.Key words : patchouli oil, patchouli alcohol, fractinational distillation, antibacterial

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Journal Info

Abbrev

3

Publisher

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...