Jurnal Ilmiah Kedokteran Wijaya Kusuma
Vol 3, No 1 (2014): Edisi Maret 2014

INTERLEUKIN-6 (IL-6) LEVEL AS AN INDIKATOR OF PROGRESIVITY RHEUMATOID ARTHRITIS (RA) DISEASE

Tania, Putu Oky Ari (Unknown)
Simamora, Dorta (Unknown)
Parmasari, Wahyuni Dyah (Unknown)
Rahmawati, Febtarini (Unknown)

Article Info

Publish Date
12 Jun 2017

Abstract

Rheumatoid Arthritis (RA) is autoimmune disease that attacks joints and synovial tissues. Rheumatoid Arthritis is characterized by inflammation that involves production of cytokines such as Interleukin 6 (IL-6). Increasing of interleukin 6 has correlation with activity and progressivity of the disease. This research was designed to know whether IL- 6 could be used as indicator progressivity of RA. The method that used for measuring IL-6 level is ELISA (Enzyme Linked Immunosorbent Assay), using the principle antigen-antibody binding. In early stage there were 9 persons (S01, S02, S03, S04, S07, S08, S09, S10 and S14) with of IL-6 level (mean : 3.640 pg/mL), intermediate stage there were 3 persons (S06, S13 and S15) with IL-6 level (mean : 12.453 pg/mL), late stage : 3 persons (S05, S11 and S12) with IL-6 level (mean : 59.349 pg/mL).

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Journal Info
Jurnal Ilmiah Kedokteran Wijaya Kusuma
Website

Abbrev

JIKW

Publisher

Universitas Wijaya Kusuma Surabaya

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published ...