Jurnal Ilmiah Kedokteran Wijaya Kusuma
Vol 2, No 1 (2013): Edisi Mei 2013

TOXICITY OF 2-METHOXYETHANOL ON BALB-C MOUSE SPERMATOGENESIS

Tania, Putu Oky Ari (Unknown)

Article Info

Publish Date
12 Jun 2017

Abstract

The research was designed to find out the toxicity of 2-methoxyethanol (2-ME) to the number of spermatogenic cells. Ten mice divided into 2 groups, control group was administered by 0.5 % CMC (negative control) and treatment group were administered by 2-ME dose 100 mg/kg body weight. Days thirteenth until sixty thirth, the mice were administered by aquabides orally, andat  the end of the treatment, the mice were sacrified.  The number of spermatogenic cells were observated histologically with Hematoxylin-Eosin staining. The observation shows that 2-ME decreases the number of spermatogenic cells, especially spermatocyte I. Exposure of 2-ME destructs anatomy of tubulus seminiferusin testicular, which is affects degradation of ephitellium and atopy of testicular.

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Journal Info
Jurnal Ilmiah Kedokteran Wijaya Kusuma
Website

Abbrev

JIKW

Publisher

Universitas Wijaya Kusuma Surabaya

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published ...