Indonesian Journal of Pharmaceutical Science and Technology
Vol 5, No 2 (2018)

Antioxidant Activity of Combination Ethanol Extract of Turmeric Rhizome (Curcuma Domestica Val) and Ethanol Extract of Trengguli Bark (Cassia Fistula L) with DPPH Method

Triyono, Triyono (Unknown)
Yohana Chaerunisaa, Anis (Unknown)
Subarnas, Anas (Unknown)



Article Info

Publish Date
23 Feb 2018

Abstract

Turmeric rhizome (Curcuma domestica Val) and Trengguli bark (Cassia fistula L) contain antioxidant compounds which can be determined by 1,1-Diphenyl-2- Pycrylhydrazyl (DPPH) free radical inhibition method. This research was conducted to determine DPPH free radical inhibition by ethanol extract of turmeric rhizome, the ethanol extract of trengguli bark, and a combination of turmeric rhizome extract - trengguli bark extract (1:1,5) with ascorbic acid as a comparison. Identification of secondary metabolite classes is performed by phytochemical screening. Antioxidant activity was performed by inhibition of free radical color of DPPH using UV-Vis spectrophotometry. The study showed IC50 value of ascorbic acid, as a comparasion, is 3,14 μg/mL. While ethanol extract of trengguli bark has the best antioxidant activity with IC50 value 10,98 μg/mL compare to combination ethanol extract of turmeric rhizome - trengguli bark (1 :1,5) and ethanol extract of turmeric rhizome with IC50 value is 13,70 μg/mL and 41,95 μg/mL, respectively.Keywords: Antioxidant, Curcuma domestica, Cassia fistula, DPPH Method

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Journal Info

Abbrev

ijpst

Publisher

Subject

Computer Science & IT Medicine & Pharmacology

Description

Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan ...