eJurnal Kedokteran Indonesia
Vol 5, No 1 (2017): Vol 5, No 1 (2017): April

The Efficacy of Probiotic in Adults with Acute Infectious Diarrhea

Mawin Mahen (Faculty of Medicine Universitas Indonesia)
Aulia Rizka (Unknown)

Article Info

Publish Date
21 Apr 2017


Diarrhea is a global health problem with high morbidity and mortality. In developing countries, acute diarrhea is most commonly caused by infectious pathogens. Regardless of the cause, diarrhea is primarily treated by fluid replacement therapy to decrease the risk of dehydration and death, although it does not affect the duration of diarrhea. Probiotics are able to shorten the duration of diarrhea in children, but its efficacy in adults is unclear. This study aimed to evaluate the benefit of probiotic in reducing the duration of acute diarrhea in adults as compared to placebo. Systematic search was done using four databases: PubMed, Scopus, ProQuest, and Embase, without limit on the year of publication. Randomized clinical trials were selected as the appropriate study design to answer the clinical question and two studies were considered relevant for appraisal. In conclusion, probiotics could improve the recovery of acute infectious diarrhea in adults (level of evidence 1b) however more studies should be carried out since only very few strains of probiotics have been investigated.

Copyrights © 2017

Journal Info





Medicine & Pharmacology


Elektronik Journal Kedokteran Indonesia (eJKI) is a peer-reviewed and open access journal that prioritize the publication manuscript of students (medical education program, magister/specialist, doctoral). This journal publishes editorial, research article, reviews, evidence-based case report, and ...