Folia Medica Indonesiana
Vol. 54 No. 2 (2018): June

Dynamic Concentric Activity Can Increase the GLUT-1 Expression on Muscle Membrane on Diabetic Mice

Havid Yusuf (Department of Physical Education, Health and Recreation, IKIP Budi Utomo, Malang)
Dini Safitri (Department of Physical Education, Health and Recreation, IKIP Budi Utomo, Malang)



Article Info

Publish Date
05 Jul 2018

Abstract

Diabetes mellitus is a type of a degenerative disorder that affects the body's ability to make or use insulin. The resistance of insulin may affect the decline of GLUT-1 expression of diabetic muscle, causing impaired glucose uptake. Dynamic concentric activity is one of the activity models based on muscle-contraction-type activity. This study used experimental method. The instrument in this study was a treadmill (brand: modified columbus treadmill) with 10-degree slope (uphill), with the velocity of 21 cm/sec (the speed options showed on the treadmill), and the duration of the exercise was 16 minutes and 30 seconds (measured using stopwatch). In this study, there were 3 groups of samples, Normal (K0), DM (K1), and DM + Dynamics Concentric (K2). Based on statistical results of correlation value p=0.00 (p<0.05), there was significant correlation between blood sugar level and GLUT-1. Dynamic concentric activity for diabetics had an effect in increasing the amount of GLUT-1, resulting in decreased blood glucose levels.

Copyrights © 2018






Journal Info

Abbrev

FMI

Publisher

Subject

Other

Description

Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. ...