eJurnal Kedokteran Indonesia
Vol 6, No 2 (2018): Vol 6, No. 2 (2018): Agustus

Chest X-ray evaluation of cavitary lesions among pulmonary MDR-TB patients in Kariadi Hospital, Semarang, Indonesia

Resta Farits Pradana (Radiology Department, Kariadi Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia)
Yusuf Nawawi (Department of Public Health and Community Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Indonesia Radiology Department, Moewardi Hospital, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia)
Bambang Satoto (Radiology Department, Kariadi Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia)

Article Info

Publish Date
14 Sep 2018


The objective of this study is to know the relationship between MDR-TB treatment to the changes in diameter and thickness of cavity wall on chest X-ray (CXR) 6 month and 12 months post treatment. This study was conducted in MDR-TB clinic in Kariadi Hospital, Semarang on January 2013-December 2016. We examine cavitary lesions, evaluated with CXR in pulmonary MDR-TB patients before and after 6 and 12 months of treatment course. Subjects who had been diagnosed as pulmonary MDR-TB and had received MDR-TB treatment for at least 12 months were chosen. Subjects characteristics and cavities features i.e. cavity number, diameter and wall thickness from initial and follow-up CXR 6 and 12 months of treatment were retrieved. A total of 43 patients of MDR-TB, consisted of 22 males and 21 females, was recruited. Most of the subjects aged 31-50 year old and presented with single cavity. The cavitary lesions showed significant reduction over 6 and 12 months of follow up based on CXR (p<0.001) for both diameter and wall thickness. Both diameter and wall thickness changed significantly from initial to 6 months (r=-0.87, p<0.001), initial to 12 months (r=-087, p<0.001), and 6 months to 12 months (r=-0.84, p<0.001), respectively. In conclusion, CXR as a useful diagnostic instrument that can be used to evaluate pulmonary TB, in primarily low resource setting.

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Journal Info





Medicine & Pharmacology


Elektronik Journal Kedokteran Indonesia (eJKI) is a peer-reviewed and open access journal that prioritize the publication manuscript of students (medical education program, magister/specialist, doctoral). This journal publishes editorial, research article, reviews, evidence-based case report, and ...