Journal of Tropical Pharmacy and Chemistry
Vol. 1 No. 1 (2010): Journal of Tropical Pharmacy and Chemistry

Mekanisme Aksi ?-Mangostin dari Garcinia Tetranda Pierre terhadap P.falciparum Secara In Vitro

Kuncoro, Hadi (Unknown)
Widyawaruyanti, Aty (Unknown)
Ersam, Taslim (Unknown)



Article Info

Publish Date
31 Dec 2010

Abstract

ABSTRACT Development stage of parasite resistance assay and the Globin accumulation using SDS-PAGE Method has been done to parasite P. falciparum by giving α-mangostin from G. tetranda. α-Mangostin cause delays in the development stage of the parasite P. falciparum from stage schizont to stage trofozoit and cause parasite death after 48 hour. Swelling of the parasite of abnormal parasite food vacuole occurred after administration of α-Mangostin show from the results of SDS-PAGE. Key word : α- Mangostin, G. tetranda, P. falciparum, globin accumulation ABSTRAK Telah dilakukan pengujian hambatan perkembangan stadium parasit dan akumulasi globin menggunakan metode SDS- PAGE terhadap P. falciparum dengan pemberian α-Mangostin dari G. tetranda. Diketahui α-Mangostin menyebabkan penundaan perkembangan parasit P. falciparum dari stadium trofozoit menjadi stadium skizon dan menyebabkan parasit mati setelah jam ke 48. Pembengkakan vakuola makanan parasit yang abnormal terjadi setelah pemberian α- Mangostin terlihat dari hasil SDS-PAGE. Kata Kunci : α-Mangostin, G. tetranda, P. falciparum, , akumulasi globin

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Journal Info

Abbrev

jtpc

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Medicine & Pharmacology Public Health

Description

Journal of Tropical Pharmacy and Chemistry is a Biannual, international, open access (Indexed in DOAJ, Crossref, SINTA, PKP Index, BASE, Moraref, Google Scholar), journal dedicated to various disciplines of pharmaceutical and allied sciences. Journal of Tropical Pharmacy and Chemistry (ISSN-p: ...