ABSTRACT This research aims to create a lotion formula containing essential oils of turmeric (Curcuma longa) as well as find out its activities as Aedes aegypti repellent. Turmeric rhizome steam distilled essential oil fraction to be taken. Lotion is made by mixing turmeric oil with a base with a concentration of 10%, 15%, and 20%. Preparation activity tested against Aedes aegypti mosquito that is by calculating the protection time. As a negative control use basis only, whereas the positive control used the patent lotion. From the test results obtained activity results lotion protection time in a row were 1.33 ± 0.34, 3.33 ± 0.38, 11.43 ± 1.50, and 21.67 ± 2.08 minutes. Preparations that have their greatest protection is lotion which contains turmeric oils of 20%. In addition to the activity test also tests the physical properties of turmeric oil lotion, i.e organoleptic test, pH, spreadibility test, and viscosity. All tests of physical properties were fullfilled the criteria lotion preparations. Then the pH and spreadibility tested again after being stored for 1 month. pH of lotion not experience significant differences compared to when newly created, while the spreadibility changed after being stored 1 month. Keywords: lotion, turmeric oil, repellent, Aedes aegypti ABSTRAK Penelitian ini bertujuan untuk membuat formula sediaan lotion yang mengandung minyak atsiri kunyit (Curcuma longa) sekaligus mengetahui aktivitasnya sebagai antinyamuk Aedes aegypti. Rimpang kunyit didestilasi uap untuk diambil minyak atsirinya. Lotion dibuat dengan mencampurkan minyak kunyit dengan basis dengan konsentrasi 10%, 15%, dan 20%. Aktivitas sediaan diuji terhadap nyamuk Aedes aegypti yaitu dengan menghitung waktu perlindungannya. Sebagai kontrol negatif digunakan basis saja. Dari hasil uji aktivitas didapatkan hasil waktu perlindungan lotion berturut-turut adalah 1,33 ± 0,34; 3,33 ± 0,38; 11,43 ± 1,50; dan 21,67 ± 2,08 menit. Sediaan yang memiliki waktu perlindungan terbesar adalah lotion yang mengandung minyak atsiri 20%. Selain dilakukan uji aktivitas juga dilakukan uji sifat fisik lotion minyak kunyit, yaitu uji organoleptis, pH, daya sebar, dan viskositas. Semua uji sifat fisik memenuhi kriteria sediaan lotion. Kemudian pH dan daya sebar dan lotion diuji lagi setelah disimpan selama 1 bulan. pH lotion tidak mengalami perbedaan bermakna dibandingkan dengan ketika baru dibuat, sedangkan daya sebarnya mengalami perubahan setelah disimpan 1 bulan. Kata kunci: lotion, minyak kunyit, repelan, Aedes aegypti
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