ASEAN Journal on Science and Technology for Development
Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer

Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A

Bagus Novrianto Fasni (Department of Physics, Mathematics and Science Faculty, Tanjungpura University, Pontianak 78124, Indonesia)
Yohannes Sardjono (Center of Accelerator Science and Technology, National Nuclear Energy Agency, Yogyakarta 55281, Indonesia)
Boni Pahlanop Lapanporo (Department of Physics, Mathematics and Science Faculty, Tanjungpura University, Pontianak 78124, Indonesia)



Article Info

Publish Date
24 Dec 2018

Abstract

This research aimed to determine the dose of radiation received in cancer therapy for each decay of Gadolinium atomic nuclei with isotope 157 (157Gd) in Gadolinium Neutron Capture Therapy using the SHIELD-HIT12A program. Knowing the amount of dose given to cancer tissue should aid in minimizing the damage that could occur in the healthy tissue around the cancer tissue, effectively killing only the cancer cells. The simulation employed in this research used the SHIELD-HIT12A program by providing input on beam.dat, mat.dat, detect.dat, and geo.dat files. The output data from the program comprised the value of recoil energy lost (energy absorbed into the target materials) for each of the 157Gd atomic nuclei, which was then processed by the dose determination equation to determine the dose given by the 157Gd nucleus to soft tissue. Based on the results, the amount of the dose given by each atomic nucleus 157Gd to soft tissue was 5.44 × 1011 Gy/decay.

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Journal Info

Abbrev

ajstd

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mathematics

Description

The coverage is focused on, but not limited to, the main areas of activity of ASEAN COST, namely: Biotechnology, Non-Conventional Energy Research, Materials Science and Technology, Marine Sciences, Meteorology and Geophysics, Food Science and Technology, Microelectronics and Information Technology, ...