ASEAN Journal on Science and Technology for Development
Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer

Dose Analysis of Boron Neutron Capture Therapy (BNCT) Treatment for Lung Cancer Based on Particle and Heavy Ion Transport Code System (PHITS)

Ahmad Faisal Harish (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta, Yogyakarta 55281, Indonesia)
Warsono (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta, Yogyakarta 55281, Indonesia)
Yohannes Sardjono (Center of Accelerator Science and Technology, National Nuclear Energy Agency, Yogyakarta 55281, Indonesia)



Article Info

Publish Date
17 Jul 2020

Abstract

The objectives of this study were to determine the effect of boron concentration on total dose rate for lung cancer treatment, and to determine the effect of boron concentration on the length of irradiation time for lung cancer treatment. This study was computer simulation-based using the Particle and Heavy Ion Transport code System (PHITS) by defining the geometry and components of lung cancer and the surrounding organism as the object being studied and the source of radiation used. The type of phantom used was the ORNL of an adult Asian male. The neutron source used was Kartini Reactor. The independent variable was the boron concentration of 30, 40, 50, 60, and 70 ?g/g cancer tissue and the dependent variables were the dose rate and the irradiation time. The results of this study indicated that the larger the amount of boron concentration that was injected, the higher the rate of total dose the organ received, where the total dose rate for each variation of boron concentration were 1.34 × 10-3 Gy/s, 1.71 × 10-3 Gy/s, 2.07 × 10-3 Gy/s, 2.42 × 10-3 Gy/s, and 2.78 × 10-3 Gy/s, and the larger the amount of boron concentration that was injected, the faster the irradiation time for the treatment of lung cancer was, where the irradiation time required for each variation of boron concentration was 37294 s, 29240 s, 24180 s, 20633 s, and 17996 s.

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Journal Info

Abbrev

ajstd

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mathematics

Description

The coverage is focused on, but not limited to, the main areas of activity of ASEAN COST, namely: Biotechnology, Non-Conventional Energy Research, Materials Science and Technology, Marine Sciences, Meteorology and Geophysics, Food Science and Technology, Microelectronics and Information Technology, ...