Jurnal Penelitian Farmasi Indonesia
Vol. 4 No. 2 (2015): jpfi

Evaluasi Switch Therapy Antibiotik pada Pasien Pneumonia di RSUP Dr. M. Djamil Padang

Sondang Khairani S.Farm., M.Farm., Apt (Universitas Pancasila)



Article Info

Publish Date
28 Mar 2016

Abstract

The ideal route of administration for any medication is one that achieves serum concentration sufficient to produce the desired effect withoutproducing undesired effect. Patients may be concidered candidates for switching from intravenous to oral therapy once the patient has shown clinicalimprovement and is medically stable. Purpose of this study is the evaluation of selection antibiotics and timeliness to switch therapyfrom iv to oralantibiotics therapy.A prospective observation study, data were collected from all hospitalized patients with community-acquired pneumonia at internal medicinedepartment and respiratory care department at Dr. M. Djamil Public Hospital in Padang Indonesia from September until November 2013receivedantibioticswitchtherapy. Objective criteria were used to define time to switch therapy. Result showed, 49 patients fulfill inclusive criteria in thisresearch, 41 patients from internal medicine department and 8 patients from respiratory care department. All use ceftriaxone intravena, but 32 (65%)patients wrong in switched to oral therapy antibiotics, where 23 to cefixime, 7 to azithromycin, 1 to cefadroxyl and 1 to amoxcillin + clavulanic acid.Only 17 patients (35%) with prompt conversion of intravena antibiotic therapy to oral, 12 to ciprofloxacin and 5 to levofloxacin, only 12 patients rightin time to conversion intravena to oral antibiotics, with time to switch therapy was the fifth days. 49 patients have been discharged in goodconditionand doctor's approval.

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Journal Info

Abbrev

jpfi

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Penelitian Farmasi Indonesia adalah publikasi ilmiah berkala yang terbit dua kali dalam satu tahun (September dan Maret) dan menggunakan sistem peer-riview dalam seleksi makalah. Jurnal Penelitian Farmasi Indonesia menerima naskah publikasi tentang hasil penelitian, survei dan telaah pustaka ...