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INDONESIA
Journal of Medicine and Health
Published by Universitas Kristen Maranatha
ISSN : 24425227     EISSN : -     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
Arjuna Subject : -
Articles 255 Documents
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Potency of Black Soybean (Glycine max L. Merr) and Jati Belanda Leaves (Guazuma ulmifolia Lamk) for Dyslipidemia Treatment In Vivo Prahastuti, Sijani; Hidayat, Meilinah; Kurniadi, Michael W.; Christiany, Selvina
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

Soybean Detam 1 and Jati Belanda leaves are potential alternative medicines for treating dyslipidemia. The purpose of this study is to explore  the potential of the combination of Ethanolic Extract Soybean Detam 1 (EEKD) and Jati Belanda (EEJB) in lowering LDL cholesterol and triglycerides compared to single extract and Simvastatin. Using a real laboratory experimental method with CRD, a total of 36 male Wistar rats were divided into 6 groups and administrated for treatment of 28 days. The results showed a significant decrease of LDL cholesterol as well as triglyceride in NC  as compared to P1, P2, P3 (p <0.05) and no significant difference with PC (p> 0.05). The highest suppression of LDL cholesterol between P1 with P2 and P3 is (p <0.05) while the triglyceride is between P1 and P2 (p <0.05). This study concludes that the combination of EEKD 10 mg, 20 mg EEJB, EEKD 30 mg and EEJB 30 mg is significantly lowering LDL cholesterol and triglyceride. The combination of EEKD 10 mg, 20 mg EEJB is the highest compression of LDL cholesterol and triglyceride, and has an equivalent effect with simvastatin in lowering LDL cholesterol and triglycerides in male Wistar rats induced with high fat diet. Keywords: LDL cholesterol, triglycerides
Generalized Lymphadenopathy due to Chronic Lymphocytic Leukemia (CLL) : 18F-FDG PET Imaging Hidayat, Basuki; Hutomo, Febby; Yudistiro, Ryan; Mulyanto, Ivana D.; Budiawan, Hendra; Masjhur, Johan S.
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

Lymphadenopaty is a common clinical finding with a broad differential diagnosis, withCarcinoma of Unknown Primary (CUP) as one of it’s most common causes. Flourine-18 fluoro-2 deoxy glucose (18F- FDG) positron emission tomography (PET) is a Nuclear Medicinescintigraphy procedure commonly used to localize suspected a primary lesion by depicting ametabolic status. However, in the expertise of 18F FDG PET study, clinical finding andepidemiologic data must be considered to get a better conclusion. We describe 18F-FDG PETstudy in the presence of generalized lymphadenopathy due to chronic lymphocytic leukemia(CLL), a rare disease which is initially suspected of having CUP.Keywords: 18F-FDG PET, lymphadenopathy, lymphoma, leukemia
Prevention and Treatment of Early Childhood Caries (ECC) ., Jeffrey
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

Early Childhood Caries (ECC) is a chronic disease that can be prevented. It commonlyaffects children involving in one or more decayed (with lesions or not) teeth, missing teeth (dueto caries), or teeth with fillings in children aged under 71 months. The disease is sometimesoverlooked, but this condition usually affects the general health of children. Early detection ofEarly Childhood Caries (ECC) can prevent problems which are harmful to children. Therefore,the ECC must be prevented and for teeth that have had dental caries they should be givenproper treatment so as not to worsen and affect the quality of life in children. Prevention of thisdisease is a significant component in any health program to prepare for the optimal basis forthe oral health of children. This condition will become a serious health problem if not handledproperly, and it is a major health problem for health providers throughout the world.Primarypreventive must be initiated since a woman getting pregnant.Keywords: Early Childhood Caries (ECC), prevention, treatment
Subchronic Treatment of Combination Extract Detam 1 Soybean and Jati Belanda Leaves has No Toxic Effect on Function, Weight, and Histopathological of Wistar Rat Kidney Hidayat, Meilinah; Prahastuti, Sijani; Chikita, Vibiola; Safitri, Dewi; Rahmawati, Siti F.; Soemardji, Andreanus A.
Journal of Medicine and Health Vol 1, No 4 (2016)
Publisher : Maranatha Christian University

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Abstract

The combination of Detam 1 soybean and Jati Belanda leaves proved to have effect of weight loss. Since it will become longterm using, toxicity effectvresearch is needed.  This study was conducted to determine the effect of subchronic combination of ethanol extract of soybean Detam 1 (EEDS) and Jati belanda (EEJB) on kidney function, with parameters: urea and creatinine, macroscopic and histopathological of kidney. This study were conducted on 120 Wistar rats (60 males, 60 females), 90 days (treatment group) and 120 days (satellite group). Rats were divided into six treatment groups. Test results of urea and creatinine levels of all treatment groups was lower than control group (p <0.05). The treatment turned out to have a good effect on kidney function. Kidney weight of all groups showed no significant difference with the control group (p> 0.05). Histopathological score interpretation’s result of low dose group male and female kidney rats were not disturbed. In conclusion, the combination of EEDS and EEJB  have a good effect on kidney function, did  not lead to changes in organ weight and at low doses did not cause disturbance of  renal histopathology. Key words: combination of soybean jati Belanda, subchronic treatment, kidney function, kidney’s  weight, kidney’s histopathology
Difficulty in Diagnosing Secondary Peripheral Chondrosarcoma: Radiology versus Anatomical Pathology Ruhimat, Undang; Hendarin, Arie
Journal of Medicine and Health Vol 1, No 4 (2016)
Publisher : Maranatha Christian University

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Abstract

Chondrosarcoma is a malignant tumor derived from bone cartilage. This tumor can be either primary or secondary. Secondary chondrosarcoma has some differences compared to the primary type i.e. the incidence is rarer, the younger age group, and many are low grade. The authors report a case of a 26-year-old man came to Hasan Sadikin Hospital with a chief complaint of a lump in the right thigh with mild pain since 5 months before consulation that is increasingly enlarging. After undergoing physical and radiological examinations, the patient was diagnosed with suspect chondrosarcoma in right thigh. Histopathologic examinations were performed 2 times, one of which used ultrasound guidance, giving a diagnosis of chondroma in right thigh. However the lesion was finally treated as chondrosarcoma. We suspected that the patient was more likely to suffer from secondary peripheral chondrosarcoma originating from malignant transformation of multiple osteochondromas. As widely known, it is almost impossible to differentiate between the low grade chondrosarcoma and chondroma with full certainty and this poses a classical problem in diagnostic medicine. Case described here was an example of the difficulty in distinguishing between these two diseases. Key words: secondary chondrosarcoma, peripheral chondrosarcoma, chondrosarcoma arising  in osteochondroma
Effects of Pomegranate Peel (Punica granatum L.) Extract as an Anthelmintic Amelia, Monica; Jasaputra, Diana K; Tjokropranoto, Rita
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Helminths infections caused by Soil-Transmitted Helminths (STH) are found in manypeople living in developing countries, especially in rural areas. People often use pomegranate asan anthelmintic. The aim of this research is to find out the effects of pomegranate peel (Punicagranatum L.) as an anthelmintic to female Ascaris suum in vitro. The research on the effects ofpomegranate peel extract has been conducted on 900 female Ascaris suum in vitro. Ascaris suumare divided into 5 groups, group I: pomegranate peel extract of dose 25%, group II: pomegranatepeel extract of 50%, group III: pomegranate peel extract of 75%, group IV: 0.9% NaCl as anegative control, and group V is given mebendazole 0.5% as a positive control. The meanpercentage of dead worms in group I is 39%, in group II 61%, while in group III 82%, but itspotential is lower than mebendazole, which kills 100%. The treatment using pomegranate peelextract of 25%, 50% and 75% respectively has significant differences with p < 0.05 againstnegative control (NC) using a 0.9% NaCl. The research concludes that the pomegranate peelextract has an anthelmintic effect against Ascaris suum females in vitro.Keywords: pomegranate peel extract, anthelmintic effect, in vitro
Effect of Chewing Xylitol Gum on Salivary Volume and Acidity Angwarmase, Alfonsa; Tih, Fen; Hidayat, Meilinah
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Dental caries or tooth decay is a result of the production of acid from fermentation ofbacteria that destroy tooth tissue. It can be prevented by maintaining the stability of salivaryvolume and acidity. Chewing xylitol gum is beneficial for increasing salivary volume andacidity. The aim of the study is to determine the effect of chewing xylitol gum on salivary volumeand acidity. The study is a quasi experiment conducted to 30 males aged between 17-25 yearsold. Pre and post treatment’s salivary volume are measured with measuring cup. Pre and posttreatment’s salivary acidity are measured using a pHmeter with 0,1 accuracy. Data areanalyzed with paired “t” test (a = 0,05). Average salivary volume after chewing xylitol gumincreased very significantly from 0,26 mL to 13,37mL (p=0,000). Average salivary acidity afterchewing xylitol gum increased very significantyly from 6,47 to 7,36(p=0,000). The researchconcludes that chewing xylitol gum increases salivary volume and acidity.Keywords : dental caries, xylitol, salivary volume, salivary acidity
Howes’ Analysis Measurement of Rumah Sakit Gigi dan Mulut Maranatha Bandung Patients Eunike, Evelyn
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

Howes’ Analysis is an important tool in orthodontic treatment,as it can analyze abnormalities of teeth and jaw, to help diagnose and plan dental care. The aim of this study was to compare the length and width of the dental arch and the the apical base patients of Maranatha Dental and Mouth Hospital (Rumah Sakit Gigi dan Mulut Maranatha) / RSGM and Howes Analysis standard of Caucasian Race which considered to be the reference in determining of orthodontic treatment plan. The subjects consisted of 30 patients who met the inclusion criteria and the results data were analyzed by unpaired t test. The measured variable is the length of the dental arch, the width of the dental arch, and the width of the apical base, and calculated into Howes’ Index. The results showed that there were significant differences in the measurement of the length and width of the dental arch and the Howes Index; whereas the measurement of the apical base there was no significant difference between the results of the study and the reference of Caucasian Race. Conclusion, the length and width of the dental arch and the Howes’ Index did not differ between RSGM Bandung patients with Caucasian race standards whereas the apical base width was different.Keywords: Caucasian people, Howes’ analysis, Howes’ index, Maranatha Dental and Mouth Hospital Bandung
Blood Calcium Level and Its Correlation with Calcium Daily Intake, Calcium Supplementation & Clinical Symptoms in Women with Premenstrual Syndrome Hidayat, Meilinah; Wardani, Komang RP; Purba, Bertha M; Apreza, Rendhy T
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

Premenstrual syndrome (PMS) is complex of symptoms that occur during the luteal phase of the menstrual cycle. This study aimed to observe blood calcium levels differences between the patient and not the PMS, list the average intake of calcium / day among subjects, statistically analyze the relationship between calcium intake and blood calcium levels, and examine the effect of calcium supplementation on blood calcium levels and symptoms of PMS. We examined blood levels of calcium, analytical survey method using a cross-sectional study, experimental methods and PMS symptom questionnaires. The results showed that in the group of subjects SPM average blood calcium level, and the mean intake of calcium / day were lower than in non-PMS and showed a fairly correlation between the intake of calcium per day with blood calcium levels in SPM subjects. There is a significant relationship between increased calcium blood calcium levels and symptoms of PMS. The conclusions: 1. there are differences in blood calcium levels and 2. intake of calcium per day between patients with PMS and not PMS, 3. Calcium intake is significantly associated with calcium level in the PMS and 4. calcium supplementation affects blood calcium levels and reduce symptoms of PMS.Keywords : average calcium intake, blood calcium, calcium supplementation, Premenstrual Syndrome (PMS)
Volume 1 Topic Index (Indonesian) Editor, Team
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

Volume 1 Topic Index(Indonesian)

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