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INDONESIA
Jurnal Ilmiah Manuntung
ISSN : 2443115X     EISSN : 24771821     DOI : -
Core Subject : Agriculture,
Jurnal Media Pertanian dipublikasikan dalam Bahasa Indonesia dan diterbitkan dua kali dalam setahun. Jurnal ini mempublikasikan artikel hasil penelitian dan artikel review bidang ilmu Agronomi secara luas. Semua tulisan yang masuk hendaknya bukanlah hasil plagiat dan belum dipublikasikan. Artikel akan di review oleh editor dan hasilnya akan di komunikasikan dengan penulis.
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Articles 169 Documents
KEMAMPUAN PENGHAMBATAN RADIKAL BEBAS HAND SANITIZER EKSTRAK METANOL DAUN SEPAT(Mitragynaspeciosa) Niah, Rakhmadhan; Ariani, Novia
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.126 KB) | DOI: 10.51352/jim.v6i1.314

Abstract

Leaves Sepat (Mitragynaspeciosa) is a plant of Kalimantan. These plants are often used traditionally to reduce blood sugar and antibacterial. The effectiveness is related with strong antioxidant activity in flavonoid compounds. Flavonoid compounds work through the mechanism of capturing free radicals, reducing oxidative stress. The purpose of this study was to measure the percentage of free radical inhibition in the hand sanitizer of methanol extract of leaves Sepat (Mitragynaspeciosa). Sample extraction by maceration method using methanol. Qualitative analysis of chemical compounds with certain eluents using Thin Layer Chromatography (TLC). The antioxidant activity test using the DPPH immersion method (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm. The largest percentage of free radical inhibition was obtained in a hand sanitizer concentration of 80 ppm, which is 51.07 ppm.
TOTAL FLAVONOID DAN EFEKTIVITAS EKSTRAK ETANOL BIJI KELOR (MORINGA OLEIFERA L) ASAL KOTA PALU SULAWESI TENGAH TERHADAP HISTOPATOLOGI PANKREAS TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) YANG DIINDUKSI STREPTOZOTOCIN Anggi, Viani; Tandi, Joni; Veronika, Veronika
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

This study aims to determine the content of flavonoid and the effect of ethanol extract of moringa seeds on the regeneration of pancreatic ? cells in male white rats streptozotocin induced diabetes. This study method used has total flavonoid equivalent quercetin by spectrophotometry uv-vis and to regeneration of pancreatic ? cells in male white rats used 30 test animals,namely male white rats divided into 6 groups, each group consisted of 5 male white rats with details of group I as normal control, Group II as negative control given 0.5% Na-CMC suspension, Group III as positive control given glibenclamide suspension and in Groups IV, V, and VI were given with each dose of 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BB. Histopathological damage picture of the pancreas was observed by staining HE using a 400x magnification olympus Cx21 microscope. The results showed that the ethanol extract of moringa seeds contained secondary metabolites, namely flavonoids, alkaloids, saponins and tannins. The results showed has total flavonoid equivalent quercetin of moringa seeds is 1,26% and regeneration of pancreatic ? cells in male white rats streptozotocin induced diabetes of Moringa seed ethanol extract at a dose of 400 mg/kg BB can have an effect on the regeneration of ? cells in the pancreas of white diabetic male rats.  
POTENSI DAUN MANGROVE (RHIZOPORA MUCRONATA) SEBAGAI ANTIDIABETES Sain, Usman; Sukma, Dinda Noor; Simatupang, Bena Septariama
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

Rhizopora mucronate is a typical mangrove plant that easly found on the coast of Muara Badak Beach, Kutai Kartanegara Regency, East Borneo, Indonesia. The purpose of this research is to know the activity of  active compound from mangrove Rhizopora mucronate leaves that have the potencial as antidiabetic. Samples of R. mucronata mangrove leaves were taken at Muara Badak beach region. Leaf samples that have been dried, are extracted by maceration using methanol solvent and followed by a partition extraction process using n-hexane solvent. The methanol and n-hexane extracts from R.mucronata mangrove leaves were obtained, followed by phytochemical tests (alkaloid, flavonoid, steroid, terpenoid, phenolic compounds, tannin, and saponin) qualitatively. Then the antidiabetic activity was tested using an oral glucose tolerance test method. Phytochemical test results of methanol and n-hexane extracts of R.mucronata mangrove leaves are positive contained group compounds; alkaloids, flavonoids, tannins and phenolics. The percentage decrease in blood glucose levels of mice for positive control (Glibenclamide 0.05 mg / kgBB) was 21.81%, methanol extract for group III (dose 62.5 mg / kgBB) 67.86%, Group IV (dose 125 mg / kgBB) 58.74% and Group V (group V (dose 62.5 mg / kgBW) 67.86%, Group IV (dose 125 mg / kgBW) 58.74% and Group V (group V (dose 62.5 mg / kgBW) dose 250 mg / kg) 36.72%. Then the percentage decrease in blood glucose levels of mice for n-hexane extract; Positive control was 11.60%, Group III (dose 62.5 mg / kgBW) was 20.1%, Group IV (dose 125 mg / kgBW) 7.83% and Group V (dose 250 mg / kgBW) 42.7%. The methanol extract of R.mucronata mangrove leaves at a dose of 62.5 mg / kgBB has the best antidiabetic activity. Whereas n-hexane extract has the best antidiabetic activity at a dose of 250 mg / kgBW. Thus the methanol and n-hexane extract of Rhizopora mucronata mangrove leaves has the potential as an antidiabetic.  
UJI FITOKIMIA DAN ANTIOKSIDAN EKSTRAK ETANOL PROPOLIS LEBAH KELULUT (TETRAGONULA IRIDIPENNIS) DARI SAMARINDA KALIMANTAN TIMUR Khairunnisa, Binti; Rosamah, Enih; Kuspradini, Harlinda; Kusuma, Irawan Wijaya; Sukemi, Sukemi; Tandirogang, Nataniel; Arung, Enos Tangke
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

The study aims to identify the secondary metabolite compounds contained in the ethanol extract Propolis Tetragonula Iridipennis and determine the antioxidant activity. Propolis is extracted from the beehive of Kelulut (Tetragonula Iridipennis) with a method of maceration of ethanol 96% produce a yield of 66.73%. Propolis extract contains alkaloid compounds, flavonoids, triterpenoids, tannins and carbohydrates. Propolis extract tested its antioxidant activity using the DPPH method (1.1-diphenyl-2-picrylhydrazyl) with a wavelength of 514 nm. Results showed a percentage of propolis extract free radicals 59% in concentrations of 100 ppm with IC50 33.74 ppm so that propolis extract is potentially as an antioxidant.  
PERBANDINGAN FISIK FORMULA LIPSTIK DENGAN BASIS LEMAK TENGKAWANG (ILLIPE BUTTER) DAN LEMAK COKLAT (COCOA BUTTER) Warnida, Husnul; Sukawaty, Yullia; Ardhita, Fazri Wisnu
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

Illipe butter and cacao butter have alike physical characteristic. Hence, illipe butter is one of CBS (cacao butter substitute) in food industry. The studi aims to compare the physical properties of illipe butter based lipstick with cacao butter based lipstick. Illipe butter in the study is a vegetable fat from the nut of Shorae mecistopteryx, it has a melting point of 29 ° C. The study was conducted at Pharmaceutical Technology Laboratory of Stikes Samarinda. Lipstick bases consist of illipe butter, cacao butter, carnauba wax, beeswax, lanolin and castor oil. Physical evaluation of lipstick includes homogeneity test, pH test, meting point test, hardness test, patch test, and sensory evaluation. The results showed that all lipstick formulas were homogeneous, stable, and no discoloration during 14 days. The average pH of all lipstick formulas is 5.9. Melting point of illipe buteer based lipstick is 58-59 ° C and 59-60° on cocoa butter based lipstick. Illipe butter brown fat base. Hardness level of illipe butter based lipstick is 433-833 grams, while cocoa butter based lipstick has a hardness level more than 1000 grams. Panelists in sensory evaluation preferred illipe butter based lipstick.  
Hubungan Kadar Natrium Serum dengan Outcome Klinis pada Pasien Cedera Kepala Berat di RSUD Abdul Wahab Sjahranie Samarinda Rivaldi, Achmad; Ibrahim, Arie; Siagian, Loly Rotua Dharmanita
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.125 KB) | DOI: 10.51352/jim.v6i1.296

Abstract

Recently, Traumatic Brain Injury (TBI) has high mortality in the world. In severe TBI, secondary brain injury can occur. ElectrSolyte disorders are the most common in secondary brain insult especially sodium disorders. It remains unclear whether hyponatremia or hypernatremia can cause worse clinical outcome in TBI patients. This study aimed to determine association between serum sodium level with clinical outcome in severe TBI patients at RSUD Abdul Wahab Sjahranie Samarinda. A cross sectional analytical study by taking samples to the patients with diagnosed severe TBI (GCS ≤ 8) which were hospitalized at RSUD Abdul Wahab Sjahranie Samarinda in the period of January-December 2018 that complied inclusion and exclusion criteria. Research variables are sodium serum level and clinical outcome that was assessed by structured interviews for Glasgow Outcome Scale (GOS). The relationship between variables was done using the Fisher's Exact test. A total of 41 severe TBI patients were administered. The characteristics of the sample were the most patients in 20s-40s (46.3%), patients were dominated by male (82.9%) and the most common CT scan characteristic were epidural hematoma (29.3%). The most of patients showed normonatremia in 25 patients (61%), 9 patients (22%) had hypernatremia and 7 patients (17.1%) had hyponatremia. The most clinical outcome on severe TBI patients were worse outcome with 70.7% while good outcome with 29.3%. Statistical result showed there’s no association between serum sodium level (hyponatremia and hypernatremia) with clinical outcome in severe TBI patients with p values, 1.000 and 0.225, respectively. There’s no association between serum sodium level with clinical outcome in severe TBI patients.
IDENTIFIKASI PENGARUH TAKARAN BAHAN DASAR TERHADAP KUALITAS MIE BASAH BERDASARKAN DAYA SERAP AIR DAN METODE DOE Nurrohkayati, Anis Siti; Binyamin, Binyamin; Khairul, Muhammad
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

Wet noodles are one of the foods that are favored by all people, especially in Indonesia. Wet noodles are made from basic ingredients of wheat flour or wheat flour. So far there have been many innovations of wet noodles with basic ingredients apart from wheat flour. The difference in the basic ingredients and additional ingredients can affect the quality of the noodles. However, it is not yet known whether the effect of the quality of the wet noodles is influenced by the type of flour used, the amount of the basic ingredients, or whether there is an effect of the extracts of other ingredients on the quality of the wet noodles. This is the reason for this research. Thus, this study aims to determine the types and differences in the use of basic ingredients in making wet noodles that can affect the quality of wet noodles. Measurement parameters used are by calculating the level of water absorption. The combination of wheat flour, cassava flour, and seaweed were used in this study. Calculation analysis is performed using the Taguchi method. The Taguchi method is the methodology in the world of Engineering which can be used as a method to measure or improve the quality of a product, as well as minimize costs. Wet noodle making experiments were conducted according to the Taguchi Design of Experiments (DOE) method. The repetition of the experiment was carried out eight times according to the orthogonal array (OA) matrix used. There are 5 control factors and 3 noise factors that are used in this study. Control factors are wheat flour, cassava flour, eggs, salt, and seaweed. Meanwhile, the noise factor is a lot of water, a long time to rest dough, and a long time to steam. ANOVA analysis and mean effect were carried out to find out which factors had the most significant influence on the quality of the noodles.  
EFEKTIVITAS EDUKASI VIDEO UNTUK KELENGKAPAN PENJELASAN CARA PENGGUNAAN INHALER OLEH MAHASISWA APOTEKER Lorensia, Amelia; Mahmudah, Rifaatul Laila; Masruroh, Ema Arifatul; Ningrum, Navaul Setiya
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.340

Abstract

Pharmacists are one of the health workers who play a role in providing information related to explanations of how to use inhaler preparations to asthma patients. This study aims to determine the effectiveness of providing educational videos on how to use several types of inhalers (MDI, MDI with spacers, Diskus®, and Bodyaler® given to pharmacist students. This research is a pre-post design (experimental) study. Sampling was conducted using the method non random sampling using purposive technique, normality test using Shapiro-Wilk and continued.From the results of the data obtained, each assessment verbally (as explained by the subject) and motoric assessment (as demonstrated by the subject) is seen from the pre- and post-intervention Comparing the completeness of explanations both verbally and motorically, showing significant differences compared to before education, with P values ​​for MDI (P (0,000) ≤0.05), MDI with spacers (P (0,000) ≤0.05) Diskus® (P (0,000) ≤0.05), and Turbuhaler® (P (0,000) ,00.05), therefore video education has proven to be effective in increasing student proficiency. self-pharmacist to explain how to use inhalers.
Pengaruh Penggunaan Media Sangrai Pasir Putih dan Pasir Hitam Terhadap Karakteristik Rendemen dan Bilangan Asam Minyak Kemiri Dari Daerah Asal NTT. Bahadi, Silvana Kholid; Riyanta, Aldi Budi; Purgiyanti, Purgiyanti
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.401

Abstract

Candlenut (Aleurites Moluccana (L.) Willd) is a plant commodity that has the potential to be developed. Candlenut processing also varies, one of which is that candlenut oil can be made and then its benefits can be taken. In making the candlenut oil, it uses the oil press method with a press machine that has previously been roasted using black sand or white sand media. The characteristics of the candlenut oil include yield and acid number. The yield of hazelnut oil on black sand is 47.55% and on white sand is 46.80%. And the results of the acid number on black sand are 1.8% while on white sand is 2.1%. Based on these results, it can be concluded that the use of black sand and white sand as a roasting medium affects the yield characteristics and acid number of candlenut oil.