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Hubungan antara jenis asupan karbohidrat dan lemak dengan kadar small dense low density lipoprotein pada pasien penyakit jantung koroner Sofia, Sefri Noventi; Sugiri, Sugiri; Utami, Sulistiyati Bayu; Nugroho, M. Arif; Murbawani, Etisa Adi
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: small dense Low Density Lipoprotein (sdLDL) was the most atherogenic lipoprotein. Its influenced by internal and external factors including food consumption. Indonesian people mostly take a diet of high carbohydrate (CH) and fried food that believed to correlate with higher sdLDL level and predisposed to Coronary Heart Disease (CHD). There were 2 types of CH based on the processing ways, refined and non-refined CH.Objectives: The studyâ€™s purpose was to prove the correlation between different types of CH and fat intake with the sdlDL level in CHD patients.Methods: cross sectional in CHD patients hospitalized at Dr Kariadi hospital. The sdLDL and others lipid profile examined. The type and amount of CH and fat intakes per-day were collect from an interview using semi-quantitative food frequency questionnaire (SQFFQ) and food models. Pearson and Spearman test used for bivariate analysis. Confounding factors age, gender, physical activity, diabetes mellitus and smoking were analyzed. Variables with p<0,25 was included in multivariate analysis using linear regression test.Results: There were 30 samples with CHD came with acute coronary syndrome (ACS). Mean of total CH intake per day was 267.75 gram. Mean of percentage of CH from total calories per day was 55.93%. This number was higher than advised which is 30-130 gram or <45% of total calorie per day. Mean of refined and non-refined CH intake was 161.80 and 57.81 gr/day. The total CH mostly from refined CH (76%) rather than non-refined. Mean of fat intake was 68 gr/day (32.76% of total energy per day), and the mean of sdLDL level was 26,54 mg/dl. Correlation between refined CH vs non-refined CH with the sdLDL levels (r=0.328; p=0.077 vs r=-0.184;p=0.331). Correlation between fat intake and sdLDL levels (r=0.44;p=0.15). Multivariate analysis was analyzing refined CH fat intake and age with sdLDL level (r=0,28;p=0,13 vs r=0.45;p=0.01 vs r=-0.15;p=0.44). There is significant correlation between fat intake and sdLDL levels with r=0.45Conclusion: There was a significant correlation between fat intake and sdLDL levels in CHD patients. There is no significant correlation between refined and non-refined carbohydrates with sdLDL levels in CHD patients.

Efek pemberian Chlorophyllin terhadap kadar nitric oxide dan malondialdehida tikus hiperkolesterolemia Pontang, Galeh S; Johan, Andrew; Subagio, Hertanto W
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Endothelial dysfunction is well-known as an early stage of atherosclerosis. Increased oxidative stress inhypercholesterolemia triggers endothelial dysfunction that is characterized by decreased biological availability ofnitric oxide (NO). Experimental studies showed that chlorophyllin had an effective antioxidant activity.Objectives : To determine the effect of chlorophyllin on nitric oxide (NO) and malondialdehyde (MDA) level ofhypercholesterolemic rats.Methods : Post test only randomized control groupusedtwenty four male Sprague Dawley rats were randomly dividedinto four groups: without treatment (technical control/K1), hypercholesterolemic (negative control/K2),hypercholesterolemic with chlorophyllin at dose of 1,8 mg/200 g/d (P1) and hypercholesterolemic with chlorophyllin atdose of 3,34 mg/200g/d (P2). Chlorophyllin was dissolved in water and was given via nasogastric tube for 21 days afterthe rats got hypercholesterolemia. Total cholesterol level of blood was measured by CHOD-PAP method, level of NOplasma was measured by Griess reaction and level of MDA plasma was measured by TBARS method. Hypothesis testwas analyzed by One Way Anova continued by Post hoc LSD test and Kruskall Wallis by significant level of 0,05.Results :NO plasma level was the lowest in group P2 (0.203+0.015 Î¼M) and the highest in the group K2 (0,224Â±0,001Î¼M), but no difference of NO plasma level among groups (p = 0.118). There were differences in MDA plasma levelamong the groups (p = 0.001). P1 and P2 groups had lower MDA plasma level than K2 (2.40+0.11 nmol/ml), indicatedby (1.94 +0.07 nmol/ml, p=0.0001) and (1,37 +0.13 nmol/ml, p=0.0001) respectively, but still higher than K1(0.94+0.05 nmol/ml, p=0.0001).Conclusion : The treatment of chlrophyllin does not have an effect of NO plasma level, but gives an effect of lowerMDA plasma level.

Back Matter JGI Des 2015 Indonesia, Jurnal Gizi
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 1 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

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Efektifitas sinar ultraviolet terhadap cemaran bakteri patogen pada makanan cair sonde untuk pasien immune-compremissed Sulatri, Ni Luh; Yogeswara, Ida Bagus Agung; Nursini, Ni Wayan
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Food safety remained as critical concern to immune-compremissed patient. Food safety assurance can be achieved through inhibition of pathogenic bacteria by physical treatment such as UV light radiation. However, a study regarding the effect of UV light on growth of pathogenic bacteria in contaminated liquid food are scarce.Objective : To determine the effectiveness of UV light on contamination of pathogenic bacteria in liquid food for immune-compremissed patient.Methods : Randomized design with two factor which were holding time for 60 and 120 minutes and radiation exposure (0, 5, 10 and 15 minutes). The data was analyzed using ANOVA Result : The viscosity and pH of liquid foods were 20 centipoise and 7,15 respectively. Radiation of UV light on contaminated food that have been incubated for 60 and 120 minutes at 37oC showed significant increase (1-2 log cycle) on growth of pathogenic bacteria.Conclusion : Radiation of UV light on contaminated liquid food were not effective to inhibit or kill pathogenic bacteria during holding time (60 and 120 minutes).

Anak perempuan dan obesitas sebagai faktor risiko kejadian kadar gula darah tinggi pada anak sekolah dasar Pibriyanti, Kartika; Hidayati, Khairina Nur
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 2 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Prevalence of Diabetes Mellitus (DM) in Indonesia is 1.5%. Diabetes Mellitus is not only suffered by adults, but the age of adolescents and children as well. Risk factors in children include gender, obesity, mealtimes, race, age and genetics.Objective : The objective of the study was to analyze the risk factors of high blood glucose incidence in school children.Methods : This research was analytic survey with cross sectional approach. The population was all students of SD Negeri 1 Sokoboyo class IV to VI amounted to 82 students. The sample size was 82 students taken by purposive sampling technique. The independent variables include obesity and sex, as well as the dependent variable that is the blood sugar level. Test analysis used is chi-square test with significance level 5% (Î± = 0,05).Results : Most of the female sample (54.9%), 30.5% were obese and 43.9% had abnormal blood sugar levels. Girls have a 2,95 times greater risk of having high blood sugar levels than boys. Obese children have 10,25 times greater high blood glucose levels than normal children.Conclusion : Sex and obesity are associated with blood sugar levels in students class IV s / d VI SD Negeri 1 Sokoboyo Slogohimo District Wonogiri District.

Sitotoksisitas in vitro ekstrak etanolik buah parijoto (Medinilla speciosa, reinw.ex bl.) terhadap sel kanker payudara T47D Tusanti, Iin; Johan, Andrew; Kisdjamiatun, RA
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 2 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Several studies focused on phytochemical as agents of cancer prevention and co-chemotherapy. One of Indonesian plant which has edible fruit but it hasnâ€™t been completely explored is Medinilla speciosa (Reinw.ex Bl.). Objective : The aim of this study is to examine the cytotoxic activity (IC50 value) of Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract. Methods : Medinilla speciosa (Reinw.ex Bl.) fruit ethanolic extract was used in this study. The cytotoxic activity was investigated in vitro on human breast cancer T47D cell-line. The cells viability were assessed using MTT colorimetric assay. Breast cancer T47D cell lines was treated with fruit ethanolic extract (10, 25, 50, 100, 250, 500 and 1000 Âµg/ml) for 24 hour of incubation. This study also identified phytochemical compound of the fruit with thin layer chromatography (TLC). Results: The result showed that ethanolic extract of Medinilla speciosa (Reinw.ex Bl.) has moderate cytotoxicity on breast cancer T47D cell line with IC50 value of 614.50 Âµg/ml and yield the decrease of cell viability at higher concentration. Medinilla speciosa fruit can not be used as anticancer agent but chemoprevention agent. Phytochemical test showed that the fruit extract contain flavonoid and saponin compound. Conclusion: Ethanolic extract of Medinilla speciosa fruit exhibited moderate cytotocicity on breast cancer T47D cell lines with IC50 value was 614,50 Âµg/ml thus it can be used as chemopreventioan agent.

Efek konsumsi yoghurt probiotik terhadap kadar low density lipoprotein pada penyandang diabetes mellitus tipe 2 Yuliani, Kartika; Kertia, Nyoman; Lestari, Lily Arsanti
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 8, No 1 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : As one of important markers of cardiovascular complication in patients with type 2 diabetes mellitus, low density lipoprotein (LDL) shall be maintained to be in normal range. Based on previous research, consumption of probiotic yogurt contains Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis is presumed can improve LDL in patients with type 2 diabetes mellitus but the scientific evidence is still few.Objectives: To investigate the effect of probiotic yogurt on LDL in patients with type 2 diabetes.Methods: This study was double blinded randomized controlled trial which was conducted on 32 patientss with type 2 diabetes mellitus. Subjects were divided randomly into 2 groups and given 4 weeks intervention. Subjects in control group were given conventional yogurt while subjects in intervention group were given probiotic yogurt contains L. acidophilus LA5 and B. animalis subsp. Lactis Bb12. Food intake data was collected 4 times using 24-hour recall method during intervention period. LDL of subjects was measured before and after intervention.Results: There was no significant difference between LDL before and after intervention in control group (128 â€“ 148.5 mg/dL) and intervention group (130 â€“ 120.5 mg/dL). Meanwhile, LDL after intervention in control group and intervention group were significantly different (p<0.05). LDL between energy and macronutrients intake categories were not significantly different.Conclusion: Probiotic yogurt has a better LDL reduction effect in patients with type 2 diabetes mellitus than conventional yogurt, although the reduction is not significant.

Pengaruh pendidikan kesehatan bagi ibu terhadap asupan energi, aktivitas fisik dan indeks massa tubuh pada anak kelebihan berat badan Haya, Miratul; Setiawati E, Mexitalia; Margawati, Ani
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 1 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : The percentage of overweight children in Bengkulu (16.4%) is higher than the national (11.9%). Factors causing overweight is a high energy intake and low physical activity.Objective : To analyze the impact of health education for mothers in changes of maternal behavior, energy intake, physical activity level and Body Mass Index (BMI) z-score among overweight children 3-6 years old.Methode : Quasi-Experiment with non-randomized pre-post test control group design. Subjects (48 mothers) were selected purposively and divided into 2 groups (treatment and control). Health education in the treatment group was conducted 6 times in 12 weeks. Analyses were conducted by Independent t-test, Mann Whitney, Paired t-test, Wilcoxon and Covariance.Results: There was an increased in attitude score (20.9 Â± 3.52), carbohydrate intake percentage (3.7 Â± 7.30%) and physical activity level (0.04 Â± 0.01) in the treatmentÂ group. The energyÂ adequacyÂ level (-3.4 Â± 13.26%)Â and BMI z-score (-0.57 Â± 0.26) decreased in the treatment group. There were difference between the treatment and control groups in attitude, energy adequacy level, physical activity level and BMI z-score after intervention (p <0.05).Conclusion: Health education for mothers affect the positive change in mother attitude in terms of the overweight children treatment and increased physical activity level, decreased energy adequacy level and BMI z-score in overweight children.

Pemberian jus buah vitamin C dan madu menurunkan disfungsi rongga mulut pada anak akibat kemoterapi Hariani, Gusti Ayu Nyoman; Sulistyadewi, Ni Putu Eny; Kusumawati, I Gusti Ayu Wita
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 1 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Dysfunction of the oral cavity is a common side effect of chemotherapy that occurs in children who are undergoing chemotherapy. To prevent a decline in quality of life of children with cancer, immediate treatment by maintaining nutritional balance is needed. This study aimed to determine the effect of vitamin C fruit juice to dysfunction of the oral cavity in children undergoing chemotherapy at Sanglah Hospital.Methods : This was a quasi-experimental study with nonrandomized pre and posttest with control group design. Samples were taken using total sampling method, consisted of 26 children aged 3-12 years. Vitamin C intake rated by evaluation of vitamin C juice residue and dysfunction of the oral cavity were assayed by Beck Oral Assessment Scale (BOAS). The entire samples were given vitamin C fruit juice in accordance with BOAS score for 5 days. Normality test of pre-test, post-test and the difference between pre and post test data with Shapiro Wilk test showed that data were normally distributed (Î±> 0.05) so that data was analyzed using parametric test paired independent sample - test with a score of 0.001 and 95% level of significance. Results : Results of analysis showed differences of oral cavity dysfunction score before and after fruit juice vitamin C treatment. Before treatment, mean of oral cavity dysfunction score in control group was 13.1 Â± 2.1 and 12.8 Â± 0.9 in treatment group. Mean of oral cavity dysfunction score after administration of oral vitamin C fruit juice in the control group and treatment group was 10.8 Â± 1.8 and 8.2 Â± 1.4, respectively. Conclusion : There were an effect of vitamin C fruit juice and honey decrese of oral cavity dysfunction in children aged 3-12 years who were undergoing chemotherapy

HUBUNGAN PENDAPATAN, PENGETAHUAN GIZI IBU DENGAN KETERSEDIAAN IKAN TINGKAT RUMAH TANGGA DAERAH PERKOTAAN Indriana, S; Widajanti, Laksmi
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Volume 1. Nomor 1. Desember 2005
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

ABSTRACT Background: The role of fish as nutrients source is very important because fish contains nutrients that to be required the body. Many markets in the city that prepare daily consumption should not become barrier for serving fish dish in family menu. Moreover Semarang city is harbour city; the fish is easy to be accessed in Semarang. But until this time role of fish in consumption of traditional food is rare because apart of population less recognize the advantage of fish. The objective of this study is to analize the relationship between income, mother's nutrition knowledge and fish stock at household level. Method: This cross sectional study was conducted to 75 mothers who be educated minimal the end of high school in Jagalan house of village-head, district of Center Semarang, Semarang city, taken by systematic random sampling. Data analyzing with Spearman correlation test. Result: Income/capita/month from mother/household ranged between Rp 99.000,00 until Rp 937.000,00. Stage of income/capita/month that more than equal with Regional Minimum Commision is 16%, less than Regional Minimum Commision is 84%. Score of mother's nutrition knowledge ranged between 50,0 until 100,0 with rate was 83,5. For category of good nutrition knowledge, the percentage is 66,7%, enough category 30,7% and less category 2,7%. For fish stock in household ranged between 0-1 times/day. For category of less stock as much as 29,3%, enough category 53,3% and good category 17,3%. Correlation coefficient for income/capita/month was 0,284 (Ï value 0,014). For mother's nutrition knowledge, correlation coefficient was 0,466 (Ï value 0,000). Conclusion: The higher motherâ€™s Income/capita/month and nutrition knowledge, the higher fish stock in household. Keyword: Income, nutrition knowledge, mother, fish stock, household. ABSTRAK Latar Belakang: Peranan ikan sebagai bahan penyedia gizi sangatlah penting karena ikan mengandung zat-zat gizi yang sangat dibutuhkan tubuh. Banyaknya pasar di Kota Semarang yang menyediakan kebutuhan sehari-hari, seharusnya sudah bukan merupakan halangan untuk penyajian hidangan ikan dalam menu keluarga. Apalagi Kota Semarang merupakan kota pelabuhan, ikan mudah didapatkan. Namun sampai saat ini peran ikan dalam konsumsi pangan tradisional masih kecil karena sebagian penduduk kurang mengenal manfaat ikan. Tujuan penelitian untuk menganalisis hubungan pendapatan, pengetahuan gizi ibu dengan ketersediaan ikan di tingkat rumah tangga. Metode: Penelitian menggunakan metode penelitian survei masyarakat, jenis penelitian analitik, pendekatan waktu cross sectional. Pelaksanaan penelitian bulan September-Oktober 2004. Analisis data dengan uji korelasi Spearman. Populasi adalah ibu yang berpendidikan minimal tamat SLTA di Kelurahan Jagalan, Kecamatan Semarang Tengah, Kota Semarang (305 orang) dengan sampel sebanyak 75 orang. Hasil: Pendapatan/kapita/bulan ibu/rumah tangga bervariasi dari Rp 99.000,00 - Rp 937.000,00. Tingkat pendapatan/kapita/bulan yang >UMR persentasenya 16%, yang <UMR 84%. Nilai pengetahuan gizi ibu tentang ikan berkisar antara 50,0-100,0 dengan nilai rata-rata 83,5. Untuk kategori pengetahuan gizi baik, persentasenya 66,7%, kategori cukup 30,7% dan kategori kurang 2,7%. Untuk ketersediaan ikan tingkat rumah tangga, berkisar antara 0-1 kali/hari. Untuk kategori ketersediaan kurang ada 29,3%, kategori cukup 53,3% dan kategori baik 17,3%. Hasil uji korelasi Spearman untuk pendapatan/kapita/bulan diperoleh nilai rs=0,284 (p=0,014). Untuk pengetahuan gizi ibu tentang ikan diperoleh nilai rs=0,466 (p=0,000). Simpulan: Semakin tinggi pendapatan/kapita/bulan dan pengetahuan gizi ibu tentang ikan akan makin tinggi ketersediaan ikan di rumah tangga Kata kunci: Pendapatan, pengetahuan gizi, ibu, ketersediaan ikan, rumah tanggaPermalink: http://ejournal.undip.ac.id/index.php/jgi/article/view/3240

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