cover
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota semarang,
Jawa tengah
INDONESIA
JURNAL GIZI INDONESIA
Published by Universitas Diponegoro
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Arjuna Subject : -
Articles 194 Documents
Tingkat konsumsi zat besi (Fe), seng (Zn) dan status gizi serta hubungannya dengan prestasi belajar anak sekolah dasar Wadhani, Luh Putu Prema; Yogeswara, Ida Bagus Agung
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.069 KB) | DOI: 10.14710/jgi.5.2.82-87

Abstract

Background : The main problem faced by Indonesia especially in the education field is the achievement of learning in children is still low in Elementary School. Several factor that influence the learning achievement in children are internal factors, external factors and the learning methods. Nutritional status, sufticient iron (Fe) and zinc (Zn) intake is one of the important indicators to improve the growth and development of brain in children.Objective :The purpose of this study to determine the correlation between level of iron and zinc consumption and nutritional status with children’ learning achievement in Elementary School no. 1 Buduk and Elementary School no. 2 Abianbase.Methods : design of this study was used an Observational Analytics with Cross Sectional Design which has been implemented in April-May 2017 with Simple Random Sampling Technique in the 5th grade students (57 samples).Result : The result of this study showed that most of the iron (Fe) and zinc (Zn) consumption in medium category that is 64,9% and 42,1%, while the nutritional status in normal category that is 64,9%  and the learning achievement includes in good category that is 84,2%. The learning achievement related to iron (Fe) and nutritional status (p=0,000) and not associated with the level of zinc (Zn) consumption (p=0,447).Conclusion : The study showed a correlation between the level of iron (Fe) consumption and nutritional status with learning achievement and there is no correlation between the level of zinc (Zn) consumption.
Perilaku gizi dan faktor psikososial remaja obes Noer, Etika Ratna; Kustanti, Erin Ratna; Fitriyanti, Addina Rizky
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 2 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.882 KB) | DOI: 10.14710/jgi.6.2.109-113

Abstract

Background: Adolescent obesity is a complex condition involving medical, psychology and cultural issue. Changing dietary practices and an increasingly sedentary lifestyle predispose to obesity related nutritional behavior. Obese adolescents have impact on psychological problem, including stress, social discrimination, reduced self-esteem, self-dissatisfaction and resulting in lower quality of life.Objectives: This study describes nutritional behavior and psychosocial factors in overweight and obese adolescent. Methods: A qualitative study was conducted in the Public Senior High School (SMA 2) on July to August 2015, in Semarang City. In-depth-interview and Focus Group Discussion (FGD) were carried out with 20 of obese adolescent aged 15 to 17 years, 2 parents, 2 teacher and 2 friends. Thematic analysis is used to identify themes in a data.Results: The majority participants considered the timing of obese are when they reach puberty. The pattern of food habits of obese adolescents become unhealthy. Obese adolescents also feel the bullying or ridicule from friends, so that they psychologically disturbing. Environmental factors play a role in the incidence of obese adolescents, namely lack of control by parents. The parents say that obese adolescents are still in a reasonable level because the adolescent has not shown any serious health problems, but a sense of fear still owned by the parents of obese adolescents.Conclusion: The findings show obesity in adolescent has not been considered as health problem. Unhealthy diet, bullying, poor motivation and lack of peer supports are contributing factors in obese adolescent. 
Faktor pelaksanaan kesehatan reproduksi perusahaan dan dukungan keluarga dalam penentuan pola menyusui oleh pekerja (buruh) wanita di Kabupaten Kudus Fatimah, Siti; Martini, Martini; Rostyaningtyas, Dewi; Soemarmi, Amiek
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 1 (2013)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.822 KB) | DOI: 10.14710/jgi.2.1.

Abstract

Background: Indonesia still faces problems of health, especially infant and child mortality rate is quite high. One effort to overcome this problem by promotion of breastfeeding. Family problems arise when workers are women workers give birth and breastfeed. Objectives: This study aimed to determine the pattern of breastfeeding on women workers as well as the factors influencing the feeding patterns.Method: This study used cross sectional analytic survey. The research sample included women workers who had toddlers 2-5 years old and working in the industry in Kudus Regency, totaling 75  women workers (laborers) in the Djarum cigarette factory, Aroma and Norojono based and proportional random sampling. Data were collected through interviews using questionnaires and in-depth interviews. Results: The results showed that the majority (70.7%) of subjects had a basic level of education (elementary and junior high school), most (74.7%) was classified as less knowledge, most (53.5%) was classified as less supportive stance, the majority (69,3%) of breastfeeding pattern was quite good, although all subjects not exclusively breastfeed their children. Spearman Rank test showed no relation between education, knowledge, attitude, family support and company policies with breastfeeding pattern. It is advised that the company began planning the establishment of child care support coordination with the Ministry of Social Affairs, and that working women to breastfeed exclusively.Conclusion: There were no relation between education, knowledge, attitude, family support and company policies with breastfeeding pattern. Keywords breastfeeding pattern, family support, company support, women workers, cigarette manufacturing
Efek konsumsi yogurt terhadap glukosa darah puasa pada penyandang diabetes melitus tipe 2 Nuriannisa, Farah; Kertia, Nyoman; Lestari, Lily Arsanti
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 8, No 1 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.251 KB) | DOI: 10.14710/jgi.8.1.40-44

Abstract

Background: Generally, patients with type 2 diabetes mellitus (T2D) have dysbiosis condition. Dysbiosis can increase oxidative stress that leads to hyperglycemia. Previous researches showed that yogurt consumption can reduce blood glucose in T2D, so it can be used as an alternative healthy snack for T2D patients.Objectives: To investigate the effects of probiotic and conventional yogurt with dosage 100ml/day on fasting blood glucose (FBG) in T2D patientsMethods: Randomized controlled trial, double blind with pre-post group design. The 30 T2D patients from 3 publics health centre in Yogyakarta, were assigned to two groups. Each group, either control or intervention group, received 100 ml/d of yogurt for 4 weeks. FBG samples was assessed before and after intervention periodResults: FBG significantly decreased in both group, which was -27 mg/dL in control group (p<0.05) and -19 mg/dL in intervention group (p<0.05). No significant difference in FBG change between intervention and control group, but control group has greater reduction in FBG compared to intervention group. Conclusion: Conventional yogurt has no significant difference effect in FBG change compared to probiotic yogurt. 
Pengaruh asupan air putih terhadap berat badan, indeks massa tubuh, dan persen lemak tubuh pada remaja putri yang mengalami gizi lebih Mulyasari, Indri; Muis, Siti Fatimah; Kartini, Apoina
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 2 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.043 KB) | DOI: 10.14710/jgi.3.2.120-125

Abstract

Latar belakang : Remaja putri yang kelebihan berat badan dengan indeks massa tubuh (IMT) dan persen lemak tubuh tinggi berisiko menderita sindrom metabolik. Beberapa penelitian melaporkan peningkatan asupan air putih dapat menurunkan berat badan, IMT, dan persen lemak tubuh. Tujuan : Mengetahui pengaruh asupan air putih terhadap berat badan, IMT, dan persen lemak tubuh pada remaja putri yang mengalami gizi lebih.Metode : Desain penelitian adalah pre-post test design without control. Populasi adalah mahasiswa di Asrama Kebidanan Ngudi Waluyo Ungaran usia 18-19 tahun. Jumlah subjek 26 mahasiswa dipilih secara simple random sampling sesuai kriteria inklusi. Perlakuan adalah asupan air putih 30 menit sebelum makan sebanyak 500 ml selama delapan minggu, namun hanya berjalan lima minggu karena penolakan subjek. Tidak ada intervensi pada asupan makanan dan aktivitas fisik. Berat badan diukur menggunakan timbangan injak digital Omron dan persen lemak tubuh diukur dengan Bioelectrical Impedance Analyzer (BIA) merk Omron. Data dianalisis menggunakan uji Paired t test dan Wilcoxon.Hasil : Rata-rata asupan air putih, yaitu 90.82 % (±454 ml) setiap kali sebelum makan. Anjuran mengkonsumsi 500 ml air putih 30 menit sebelum makan selama 8 minggu sulit dilaksanakan sehingga perlakuan hanya berlangsung lima minggu. Tidak ada perbedaan berat badan (62.9±6.75 kg vs 62.5±6.73 kg, p=0.066) dan IMT (26.6±2.69 kg/m2 vs 26.4±2.71 kg/m2, p=0.071) sebelum dan sesudah perlakuan, namun terdapat perbedaan pada persen lemak tubuh (34.2±2.76 % vs 33.7±3.05 %, p=0.037). Tingkat asupan energi (p=0.713) dan aktivitas fisik sebelum dan sesudah perlakuan tidak mengalami perubahan.Simpulan : Asupan air putih 30 menit sebelum makan sebanyak 454 ml (90.82%) selama lima minggu pada remaja putri dengan gizi lebih yang tidak mengalami perubahan asupan energi dan aktivitas fisik tidak menurunkan berat badan dan IMT, namun menurunkan persen lemak tubuh.
Pengaruh suplementasi taburia (sprinkle) terhadap kadar hemoglobin balita gizi kurang usia 3-5 tahun di Kecamatan Lewimunding Kabupaten Majalengka Budiana, Teguh Akbar; Kartasurya, Martha Irene; Judiono, Judiono
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 1 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.68 KB) | DOI: 10.14710/jgi.5.1.34-41

Abstract

Background: Anemia is the most common nutritional problem found in the world, whichal sooccurred in under five children. Anemia is one of themain nutritional problems in Indonesia. Anemia treatment by iron (Fe) supplementation the community level were not successfull yet. This research aimed to investigate the effect of sprinkle supplementation on hemoglobin level of malnourished children aged 3-5 years.Method: Randomized pretest - posttest control group design was implemented on 66 anemic malnourished children aged 3-5 years. Study was conducted in Lewimunding subdistrict. Subjects were divided into two groups, treatment and control groups. Sprinkle supplementation and nurition education were given to treatment group for 2 months, while control group were only recieved nutrition education. All subjects treated by 400 mg Albendazol before supplementation. Data were nutrient intake collected by 24 hour Recall method. Hb was measured by Cyamethaemoglobin. Data were analyzed by Mann-Whitney,  Independent Sample Test, Wilcoxon Signed Ranks, Paired Test and linear regression method.Result: There was no difference in energy, protein, iron, vitamin B6, vitamin B12 and vitamin C on both treatment and control groups. There is no difference in hemoglobin levels between the groups before supplementation (p=0.290). Hemoglobin increased on treatment group from (11.14±0.85 mg/dl) to (12.31±0.55 mg/dl) with p=0.001. Hemoglobin also increased from (10,95 ± 0,71 mg/dl) to (11,81 ±0,53 mg/dl) in the control group (p=0.001). Sprinkle  supplementation increased by hemoglobin level  0.69 mg/dl higher than the control group (p=0.001). Multivariate analysis that hemoglobin level increased by  0.66 mg/dl higher compared to the control group after controlled by initial hemoglobin.Conclusion: Sprinkle supplementation for two months increase hemoglobin level of anemic malnourished children.
NILAI GIZI, DAYA CERNA PROTEIN DAN DAYA TERIMA PATILO SEBAGAI MAKANAN JAJANAN YANG DIPERKAYA DENGAN HIDROLISAT PROTEIN IKAN MUJAIR (Oreochromis mossambicus) Haslina, Haslina; Muis, Siti Fatimah; Suyatno, Suyatno
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Volume 1. Nomor 2. Juni 2006
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.52 KB) | DOI: 10.14710/jgi.1.2.

Abstract

ABSTRACT Introduction: Patilo is one of traditional various snacks from Gunung Kidul that is made of fermented cassava waste and cassava starch. Fermentation is intended to reduce or eliminate the HCN content of cassava and to establish special flavour. The protein content of patilo is very low, therefore it can be enriched with animal protein from fresh water fish in form of fish flour or fish protein hydrolysate (FPH). Enrichment with fish protein hydrolysate has an advantage since it will be easier to digest by human because FPH better functional properties and higher solubility.Method: The study consisted of four activities that were 1) making/producing mujair FPH, 2) producing and enriched patilo with mujair FPH, 3) analyzed the nutritive values and protein digestibility of enriched and unenriched patilo and 4) analyzed the consumers acceptability of the products. The experiments were carried out in the 1) Food Engineering and Chemistry Laboratorium of Faculty of Agriculture Technology Semarang University, 2) Pilot Plan PAU and GMSK Laboratory of Bogor Institute of Agriculture, 3) Sidoardjo Village, Tepus Gunung Kidul. Variables being studied were nutritive value and protein digestibility of unenriched and enriched patilo with mujair FPH in several consumer acceptability in terms of flavour, taste, colour and texture. The study design was a complete random design of one factor in which the FPH was added in 5%, 10% and 15% concentration, each treatment repeated 3 times. Statistical analyses used for nutritive value and protein digestibility were Anova followed by Least Significant Difference test with 0,05 level of significancy Friedman and Wilcoxon Sign Rank test were used to test the organoleptic values both in the laboratory and in the field. Result:1) The nutritive value changes of raw enriched patilo were : a) significant decrease in water and carbohydrate content, b) significant increase in ash, fat and protein content compared to the unenriched patilo, 2) The nutritive value change of fried enriched patilo were : a) significant decrease in water and carbohydrate content, b) significant increase in fat, protein and energy content compared to the unenriched patilo, 3) The protein digestibility in raw and fried enriched patilo was significant higher than that without enrichement, 4) Patilo enriched with 10% mujair FPH was mostly liked by consumer either in the laboratory or in the field in term of taste, flavour and texture as for colour, all consumers prefered the unenriched patilo, 5) The changes of the nutritive values and protein digestibility were statistically significant in the enriched patilo, however from the nutrition point of view, only the increased of protein content (six folds increase) was meaningful. Conclusion: Patilo enriched with 10% mujair FPH is the most/well accepted by laboratory panelists and field consumers, and there was six folds increase in the protein content.   Key Word: Patilo, enrichment and fish protein hydrolysate.   ABSTRAK   Latar Belakang: Patilo adalah salah satu makanan jajanan tradisional Gunung Kidul yang diolah dari ampas singkong yang difermentasi dan dicampur dengan pati singkong. Kandungan protein dalam patilo sangat rendah, untuk itu perlu diperkaya antara lain dengan sumber protein hewani dari ikan air tawar baik dalam bentuk tepung ikan atau hidrolisat protein ikan (HPI). Tujuan: Penelitian ini bertujuan untuk 1). menganalisis nilai gizi patilo 2). menganalisis daya cerna protein patilo 3). menganalisis daya terima patilo goreng tanpa dan dengan penambahan HPI mujair Metode: Penelitian ini terdiri dari empat kegiatan yaitu: 1). pembuatan HPI mujair, 2). pembuatan dan pengkayaan patilo dengan HPI mujair, 3). pengujian nilai gizi dan daya cerna protein patilo tanpa dan dengan penambahan HPI mujair dan 4). uji penerimaan patilo baik di laboratorium maupun di lapangan. Variabel yang diamati adalah kandungan gizi patilo dan daya cerna protein patilo. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap dengan 1 faktor yaitu HPI0=tanpa penambahan HPI, HPI1= penambahan HPI 5% dari berat ampas (b/b), HPI2=penambahan HPI 10 % dari berat ampas (b/b) dan HPI3=penambahan HPI 15% dari berat ampas (b/b), masing-masing perlakuan diulang sebanyak tiga kali. Analisis kandungan gizi dan daya cerna patilo dengan Anova, uji dilanjutkan dengan uji Least Significant Difference (LSD) pada taraf dan 5%. Untuk analisis uji organoleptik baik di laboratorium maupun di lapangan dengan uji Friedman. Perbedaan hasil akan dilanjutkan dengan uji lanjut Wilcoxon Sign Rank Test. Hasil: 1) Nilai gizi patilo mentah dengan penambahan HPI mujair dibandingkan tanpa penambahan HPI mujair adalah : a) terjadi penurunan kadar air dan kadar karbohidrat secara signifikan (ρ<0,05) dan b) terjadi peningkatan kadar abu, kadar lemak dan kadar protein secara signifikan (ρ<0,05), 2) Nilai gizi patilo goreng dengan penambahan HPI mujair dibandingkan tanpa penambahan HPI mujair adalah : a). terjadi penurunan kadar air dan kadar karbohidrat secara signifikan (ρ<0,05) dan b).terjadi peningkatan kadar lemak, kadar protein dan energi secara signifikan (ρ<0,05) 3). Daya cerna protein patilo mentah dan goreng dengan penambahan HPI mujair meningkat secara signifikan (ρ=0,000) dibandingkan tanpa penambahan HPI mujair pada semua konsentrasi, 4). Patilo dengan penambahan HPI mujair 10% paling disukai oleh panelis agak terlatih dan panelis konsumen anak sekolah berdasarkan skor rasa, bau dan tekstur. Untuk warna, panelis agak terlatih dan panelis konsumen anak sekolah memilih patilo tanpa penambahan HPI mujair dan 5). Secara statistik perubahan nilai gizi dan daya cerna protein bermakna kecuali untuk kadar abu patilo goreng, namun dari sudut gizi perubahan yang berarti hanya pada kadar protein yang mencapai 6 kali lipat. Simpulan: Patilo yang diperkaya dengan HPI mujair 10% paling disukai oleh panelis agak terlatih maupun panelis konsumen anak sekolah dan terjadi kenaikan secara signifikan pada kadar protein yang mencapai 6 kali lipat. Kata Kunci : Patilo, pengkayaan dan hidrolisat protein ikan    Permalink : http://ejournal.undip.ac.id/index.php/jgi/article/view/3243  
Status hidrasi, tingkat kebugaran jasmani dan daya konsentrasi anak sekolah dasar Sudrajat, Agus; Mexitalia, Maria; Rosidi, Ali
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 2 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.324 KB) | DOI: 10.14710/jgi.7.2.109-113

Abstract

Background: The dehydration correlated with physical fitness and the cognition. The cardiorespiratory fitness correlated with brain ability and working performance too. Objectives: The purpose of this study is to assess the correlation of dehydration status and cardiorespiratory fitness with the concentration of primary school children.Methods: Correlational study is done to the students aged 10-12 years old. The dehydration status is measured by urine specific gravity. The cardiorespiratory fitness is measured by harvard step test and digit symbol test is used to measure concentration. The analysis of the data using product moment to bivariate analysis and partial correlation to multivariate analysis.Results: The result showed that the average of subjects have a mild (Usg 1020.20±6.99 g/dl). The average of the subjects have a less cardiorespiratory fitness (31.27±8.00). The results of concentration ability measurement showed about of 35±12.27. The correlation analysis showed a significant correlation between dehydration status with cardiorespiratory fitness( r=-0.29, p=0.04 ), between dehydration status with concentration (r=-0.29, p=0.036) and between cardiorespiratory fitness with concentration (r=0.295, p=0.03). Partial correlation analysis showed the persistence of a significant correlation between dehydration status and cardiorespiratory fitness (p=0.02), between dehydration status and concentration (p=0.02) and between cardiorespiratory fitness and concentration (p=0.002).Conclusion: There is a significant correlation between dehydration status and cardiorespiratory fitness. There is a significant correlation between dehydration status and the concentration. There is a significant correlation between cardiorespiratory fitness and the concentration. 
Perbedaan kadar glukosa darah puasa pasien diabetes melitus berdasarkan pengetahuan gizi, sikap dan tindakan di poli penyakit dalam rumah sakit islam jakarta Syauqy, Ahmad
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 2 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.006 KB) | DOI: 10.14710/jgi.3.2.60-67

Abstract

Latar belakang :Perilaku makan yang tidak tepat dapat menyebabkan meningkatnya kadar glukosa darah penderita diabetes. Perilaku dibagi menjadi tiga domain yaitu pengetahuan, sikap dan tindakan. Tujuan penelitian :Melihat perbedaan kadar glukosa darah berdasarkan pengetahuan gizi, sikap dan tindakan pasien diabetes melitus tipe 2. Metode analisis : Jenis penelitian ini adalah penelitian yang bersifat deskriptif analitik dengan pendekatan crosssectional. Sampel sebanyak 50 responden, dalam penelitian ini adalah pasien diabetes melitus yang menjalani pemeriksaan kadar glukosa darah di Poli Penyakit Dalam Rumah Sakit Islam Jakarta. Pengetahuan gizi diukur berdasarkan indikator pengertian penyakit diabetes, prinsip dan syarat diet, penukar bahan makanan dan aktivitas atau olahraga ; tingkat sikap diukur berdasarkan indicator pemeriksaan penyakit diabetes, aktifitas/olahraga, kesadaran diet, bahan makanan dan jumlah porsi ; tingkat tindakan diukur berdasarkan indikator pemilihan makanan/minuman, kebiasaan makan, jadwal makan, aktifitas/olahraga dan bahan makanan penukar. Pengujian One Way Anova digunakan untuk menjawab pertanyaan penelitian. Hasil :Sebanyak 12 responden (24%) memiliki pengetahuan gizi kurang, 14 responden (28%) memiliki sikap yang kurang baik, 8 responden (16%) memiliki tindakan kurang. Rata – rata glukosa darah berbeda menurut tingkat pengetahuan (F = 4,448 ; p = 0,017), sikap (F = 3,930 ; p = 0,026) dan tindakan (F = 3,427 ; p = 0,041). Simpulan :Ada perbedaan bermakna kadar glukosa darah berdasarkan pengetahuan gizi, sikap dan perilaku terhadap pasien dengan diabetes mellitus tipe 2 di Rumah Sakit Islam Jakarta. Diperlukan  penelitian tentang pengaruh konseling gizi terhadap perilaku pasien agar dapat mengetahui keberhasilan Dietisien.
Pengaruh jamur tiram putih (pleurotus ostreatus) terhadap kadar glukosa darah, profil lipid dan kadar MDA pada tikus (rattus norvegicus) diabetes melitus Purbowati, Purbowati; Johan, Andrew; RMD, RA Kisdjamiatun
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 2 (2016)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.291 KB) | DOI: 10.14710/jgi.4.2.131-137

Abstract

Background : Diabetes mellitus is a chronic disease caused by acquired deficiency in insulin production by the pancreas, or by the ineffectiveness of using the produced insulin. Oyster mushroom (Pleurotus ostreatus) can help lower blood glucose levels, improve lipid profile and reduce levels of MDA.Objective : to analyze the effect of oyster mushroom on blood glucose levels, lipid profile and MDA levels in STZ induced rats as type 1 DM model. Methods : thirty Sprague Dawley rats were randomly divided into 3 groups: one positive group (1) and two treated group which received 100 mg/kgBB (2) and 200 mg/kgBB (3) oyster mushroom extract, respectively. The interventions were carried out for 30 days. The examination of blood glucose levels, lipid profile and MDA levels was before and after the intervention. The differences inthe datapre-post interventions were analyzed by paired t-test, whereas the differences between the groups were analyzed by one-way ANOVA and kruskal wallis followed by post hoc analysis. Results : the treatment group experienced a decrease in blood glucose levels, total cholesterol, LDL cholesterol, triglycerides, MDA and an increase in HDL cholesterol levels post-intervention (p < 0,001). Oyster mushroom extract with the dose of 200 mg/kg was more effective in lowering blood glucose levels, MDA levels and improving lipid profiles (p < 0,001).Conclusion : Oyster mushrooms administration lowers blood glucose levels, total cholesterol, LDL cholesterol, triglycerides, MDA and increases HDL cholesterol levels. 

Page 3 of 20 | Total Record : 194