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Hadi kuncoro
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Journal of Tropical Pharmacy and Chemistry
Published by Universitas Mulawarman
ISSN : 20877099     EISSN : 24076090     DOI : -
Journal of Tropical Pharmacy and Chemistry is a Biannual, international, open access (Indexed in DOAJ, Crossref, SINTA, PKP Index, BASE, Moraref, Google Scholar), journal dedicated to various disciplines of pharmaceutical and allied sciences. Journal of Tropical Pharmacy and Chemistry (ISSN-p: 2087-7099, ISSN-e: 2407-6090), The journal had been established in 2010, and online publication was begun in 2014. Since 2018, the journal has been published in English by Faculty of Pharmacy, Universitas Mulawarman (UNMUL) Samarinda, Indonesia in and only receives manuscripts in English.
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Efek Antimikroba Sediaan Salep Kulit Berbahan Aktif Ekstrak Etil Asetat Daun Sungkai (Peronema Canencens Jack.) terhadap Bakteri Patogen Penginfeksi Luka Bakar Ibrahim, Arsyik; Ahmad, Islamudin; Narsa, Angga Cipta; Sastyarina, Yurika
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.451 KB) | DOI: 10.25026/jtpc.v2i3.58

Abstract

Research on the effects of skin ointment dosage active ingredient ethyl acetate leaf extract Sungkai (Peronema canencens Jack.) has be done burns infection against pathogens bacteria. This study aims to determine the effective concentration of the ethyl acetate extract antimicrobial in skin ointment preparations against pathogens skin burns infection. Test material obtained by fractionation of the methanol extract of leaves Sungkai, further formulated into an ointment base, was tested to determine the effective concentration of activity. The results obtained by the concentration of effective skin ointment preparation with the active ingredient ethyl acetate leaf extract Sungkai is 4% for gram-positive bacteria: B. subtilis and S. aureus, dankonsentrasi 2% for gram-negative bacteria: P. aeruginosa and Str. mutans. Key words: P. canencens Jack, Formulation, Antimicrobials, B. subtilis, S. aureus, P. aeruginosa, Str. Mutans ABSTRAK Telah dilakukan penelitian efek sediaan salep kulit berbahan aktif ekstrak etil asetat daun sungkai (Peronema canencens Jack.) terhadap bakteri patogen penginfeksi luka bakar. Penelitian ini bertujuan mengetahui konsentrasi efektif antimikroba ekstrak etil asetat dalam sediaan salep kulit terhadap bakteri patogen penginfeksi luka bakar. Bahan uji diperoleh dengan fraksinasi ekstrak metanol daun sungkai, selanjutnya formulasikan ke dalam basis salep, diuji aktivitasnya untuk menentukan konsentrasi efektif. Hasil penelitian diperoleh konsentrasi efektif sediaan salep kulit dengan bahan aktif ekstrak etil asetat daun Sungkai adalah 4 % untuk bakteri gram positif: B. subtilis dan S. aureus, dankonsentrasi 2% untuk bakteri gram negatif: P. aeruginosa dan Str. Mutans. Kata kunci : P. canencens Jack, Formulasi, Antimikroba, B. subtilis, S. aureus, P. aeruginosa, Str. mutans.
Aktivitas Gel Mulut Berbahan Aktif Ekstrak Daun Sirih Hitam Kalimantan sebagai Antimikroba Penyebab Radang Gusi (Gingivitis) dan Gigi Berlubang (Caries) Prasetya, Fajar; Narsa, Angga Cipta
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (38.847 KB) | DOI: 10.25026/jtpc.v2i3.60

Abstract

This study aimed to test the activity of active ingredient mouth gel preparation of kalimantan black piper betle leaf extract with the main base of Hydroxy Ethyl Cellulose namely (HEC) as a mucoadhesive polymer that is able to increase the attractive forces between the active material with a layer of mucus that will extend the contact time with the active ingredient tissue targets, moreover would be increase the effectiveness of antimicrobial activity causes inflammation of the gums (gingivitis) and tooth decay (caries). Activities that have been implemented are mouth gel activity assays with Kalimantan black piper betle leaf extract as in- vitro using the agar diffusion method pitting. In testing with active oral gel preparation of black piper betle leaf extract with the main base of Hydroxy Ethyl Cellulose namely (HEC) as in vitro, it can be seen that the sample may provide the inhibitory effect of the fungus Candida albicans and the bacterium Streptococcus mutans in the presence of a clear zone indicated on the medium. Furthermore, at this stage of the dilution of the gel in twice causing decline in the effectiveness of the inhibition of both the fungus Candida albicans and the bacterium Streptococcus mutans. The results of in- vitro testing without dilution is 19.8 mm in bacteria Streptococcus mutans and 34.4 mm in the fungus Candida albicans. Keywords: antimicrobial, oral gel, black piper betle, gingivitis , cavities ABSTRAK Penelitian ini bertujuan untuk menguji aktivitas sediaan gel mulut berbahan aktif ekstrak daun sirih hitam Kalimantan dengan basis utama yakni Hydroxy Ethyl Cellulose (HEC) sebagai mucoadhesive polymer yang mampu meningkatkan gaya tarik menarik antara bahan aktif dengan lapisan mukus sehingga akan memperpanjang waktu kontak bahan aktif dengan jaringan target, selanjutnya akan meningkatkan efektivitas aktivitas antimikroba penyebab radang gusi (gingivitis) dan gigi berlubang (caries). Kegiatan yang telah dilaksanakan adalah pengujian aktivitas gel mulut berbahan aktif ekstrak daun sirih hitam Kalimantan secara in vitro dengan menggunakan metode difusi agar teknik sumuran. Pada pengujian sediaan gel mulut berbahan aktif ekstrak daun sirih hitam Kalimantan dengan basis utama yakni Hydroxy Ethyl Cellulose (HEC) secara in vitro, dapat diketahui bahwa sampel dapat memberikan efek penghambatan jamur Candida albicans dan bakteri Streptococcus mutans dengan ditunjukkan adanya zona bening pada agar. Namun pada tahap dua kali pengenceran terhadap gel terjadi penurunan efektivitas kerja penghambatan baik pada jamur Candida albicans maupun pada bakteri Streptococcus mutans. Hasil pengujian in-vitro tanpa pengenceran adalah 19.8 mm pada bakteri Streptococcus mutans dan 34.4 mm jamur Candida albicans. Kata kunci: antimkroba, gel mulut, sirih hitam, radang gusi, gigi berlubang
Efek Hemostatis Ekstrak Metanol Daun Sisik Naga (Drymoglossum Piloselloides Presl.) pada Tikus Jantan (Rattus norvegicus L.) Rahayu, Ika; Kuncoro, Hadi; Ibrahim, Arsyik
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.953 KB) | DOI: 10.25026/jtpc.v2i3.61

Abstract

The research is The Hemostatic Effect of Sisik Naga Leaves (Drymoglossum Piloselloides Presl.) Metanol Extract of Rat (Rattus norvegicus L.) has been done. This reseach’s purposes to determine the hemostatic effect, optimum dose and optimum measured time of Sisik Naga Leaves extract with bleeding time as its parameter used tail bleeding. Dose of Sisik Naga extract are 12.5 mg/kgBW, 25 mg/kgBW, and 50 mg/kgBW and NaCMC has been used as negative control, they were given twice a day in one day treatment. Tail bleeding by cutting the rat’s tail has been done on 12th, 24th, and 36th hour after the treatment. The result data was analyzed with two way Analysis of Varian (Anava) and followed BNJD test. The test results showed that bleeding time of negative control NaCMC is 143.15 seconds and bleeding time of Sisik Naga leaves extract with dose 12.5 mg/kgBW on 12th hours 82.62 second, 24th hours 60.27 second, 36th hours 76.36 second, dose 25 mg/kgBW on 12th hours 65.76 second, 24th hours 39.33 second, 36th hours 90.02 second, and dose 50 mg/kgBW on 12th hours 53.97 second, 24th hours 23.82 second, 36th hours 72.85. The best dose which optimum effect of hemostatic is 50 mg/kgBW with measured time on 24 hours after orally extract. Keyword : hemostatic, Drymoglossum Piloselloides Presl., bleeding time Abstrak Telah dilakukan penelitian efek hemostatis ekstrak metanol daun Sisik Naga (Drymoglossum Piloselloides Presl.) pada tikus jantan (Rattus norvegicus L.). Penelitian ini bertujuan untuk mengetahui efek hemostatis, dosis dan waktu pengukuran optimum ekstrak Sisik Naga dengan mengukur waktu perdarahan pada tikus menggunakan metode tail bleeding. Dosis uji ekstrak daun Sisik Naga yang digunakan adalah 12,5 mg/kgBB, 25 mg/kgBB dan 50 mg/kgBB dengan kontrol negatif NaCMC yang diberikan per oral dua kali sehari selama satu hari. Pengukuran waktu perdarahan adalah 12 jam, 24 jam dan 36 jam setelah pemberian ekstrak. Data dianalisis dengan Anava dua arah yang dilanjutkan dengan uji lanjutan BNJD. Hasil penelitian menunjukkan bahwa rata-rata waktu perdarahan kontrol negatif NaCMC adalah 143,15 detik dan rata-rata waktu perdarahan ekstrak daun Sisik Naga pada dosis 12,5 mg/kgBB pada 12 jam 82,62 detik, 24 jam 60,27 detik, 36 jam 76,36 detik, dosis 25 mg/kgBB pada 12 jam 65,76 detik, 24 jam 39,33 detik, 36 jam 90,02 detik, dan dosis 50 mg/kgBB 12 jam 53,97 detik, 24 jam 23,82 detik, 36 jam 72,85 detik. Dosis yang paling efektif sebagai hemostatis adalah pada dosis 50 mg/kgBB dengan waktu pengukuran yang paling efektif yaitu 24 jam setelah pemberian ekstrak. Kata kunci : Hemostatis, Drymoglossum Piloselloides Presl., waktu perdarahan
Uji Stabilitas Formula Krim Tabir Surya Ekstrak Umbi Bawang Dayak (Eleutherine americana L. Merr.) Ahmad, Islamudin; Agus, Adhe Septa Ryant
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.15 KB) | DOI: 10.25026/jtpc.v2i3.62

Abstract

Has conducted research on formulation and stability of sunscreen cream onion bulb extract dayak ( Eleutherine Americana L. Merr . ) . From the empirical data for the onions dayak has been used as an anti- cancer prevention and treatment by people of Borneo so it needs to be further investigated to obtain the data laboratory to support the empirical data . Several classes of secondary metabolites found in the bulbs of onions dayak alkaloids , glycosides , flavonoids , phenolics , steroids and tannins . The study was conducted as the basis for the formulation of sunscreen preparations aimed at the prevention of skin cancer . The study was conducted with bulb onions dayak extraction using Soxhlet method with solvent n - hexane , ethyl acetate , n - butanol , and ethanol as the active ingredient of the formula of making preparations . Tests conducted on formulations A and B with the concentration of garlic bulb extract dayak by 0.1% , consisting of physical stability test ( organoleptic , homogeneity ) and chemical ( pH and dosage ) in order to obtain a stable dosage formula . The test results obtained on the organoleptic test was no change in the observations made on each preparation before and after storage at room temperature on day - 7 , -14 , and -21 . Then the homogeneity test of the hedonic test results at 95% confidence level ( SNI 01-2346-2006 ) , concluded that the homogeneity of the preparation in all formulas produced in the category of smooth . Further testing on the pH stability and pH 5.5 to 8.0 to be produced that Formula A and Formula B to pH 7.0 to 7.7 with various concentrations of the extract , after 21 days of storage , inferred pH remains stable and safe dosage for used ( SNI 16-4399-1996 ) as formula sunscreen preparations made from onion bulb extract dayak . Key words : bulb onions dayak, sunscreen, formulas, test stability, skin cancer ABSTRAK Telah dilakukan penelitian mengenai formulasi dan stabilitas krim tabir surya ekstrak umbi bawang dayak (Eleutherine Americana L. Merr.). Dari data empirik selama ini bawang dayak telah digunakan sebagai pencegah dan pengobatan anti kanker oleh masyarakat Kalimantan sehingga perlu diteliti lebih lanjut untuk mendapatkan data laboratorik untuk mendukung data empirik tersebut. Beberapa golongan metabolit sekunder yang terdapat pada umbi bawang dayak yakni alkaloid, glikosida, flavonoid, fenolik, steroid dan zat tannin. Penelitian tersebut dilakukan sebagai dasar pembuatan formulasi sediaan krim tabir surya yang ditujukan untuk pencegahan terjadinya kanker kulit. Penelitian dilakukan dengan ekstraksi umbi bawang dayak menggunakan metode soxhlet dengan pelarut n-heksan, etil asetat, n-butanol, dan etanol sebagai bahan aktif dari pembuatan formula sediaan. Pengujian dilakukan terhadap formulasi A dan B dengan konsentrasi ekstrak umbi bawang dayak sebesar 0,1%, terdiri dari uji stabilitas fisik (organoleptis, homogenitas) dan kimia (pH dan sediaan) agar diperoleh formula sediaan yang stabil. Hasil pengujian yang diperoleh adalah pada uji organoleptis tidak ada perubahan pada pengamatan yang dilakukan terhadap masing-masing sediaan sebelum dan setelah penyimpanan pada suhu kamar pada hari ke-7, -14, dan -21. Kemudian pada uji homogenitas dari hasil uji hedonik pada tingkat kepercayaan 95% (SNI 01-2346-2006), disimpulkan bahwa homogenitas sediaan pada semua formula yang dihasilkan masuk dalam kategori halus. Selanjutnya pada stabilitas pH dilakukan pengujian dan dihasilkan bahwa pH 5,5-8,0 untuk Formula A dan pH 7,0-7,7 untuk Formula B dengan berbagai konsentrasi ekstrak, setelah penyimpanan 21 hari, disimpulkan pH sediaan masih stabil dan aman untuk digunakan (SNI 16-4399-1996) sebagai formula sediaan tabir surya berbahan ekstrak umbi bawang dayak. Kata kunci: umbi bawang dayak, tabir surya, formula, uji stabilitas, kanker kulit
Potensi Tumbuhan Libo (Ficus variegata, Blume) sebagai Sumber Bahan Farmasi Potensial Rijai, Laode
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.053 KB) | DOI: 10.25026/jtpc.v2i3.63

Abstract

Libo (Ficus varieagata) merupakan tumbuhan liar yang belum termanfaatkan dalam bentuk apapun, termasuk secara tradisional karena tumbuhan ini memiliki latex pada buah dan kulit batangnya dan jika latex tersebut mengenai kulit menimbulkan gatal-gatal bahkan terjadi iritasi. Sifat ini yang menyebabkan tidak disukai hewan pemakan buah sehingga buahnya terpelihara dengan baik. Buah Libo yang telah matang di pohon akan jatuh ke tanah lalu tumbuh menjadi pohon Libo dewasa.Potensi tumbuhan Libo berbuah terus menerus dan buahnya tidak disukai hewan pemakan buah sehingga populasi tumbuhan Libo terpelihara dan terus berkembang. Telah dilakukan berbagai penelitian terhadap buah Libo kaitannya dengan potensi kefarmasian dan terbukti berpotensi sebagai sumber bahan antioksidan, sitotoksik atau antikanker, pembasmi larva A. aegypti, dan sebagai antibakteri. Potensi-potensi tersebut dapat dimanfaatkan sebagai pengawet, obat antikanker, dan sumber antibiotik jika penelitiannya dilakukan secara detail. Buah Libo juga mengandung golongan metabolit sekunder yang sangat bervariasi sehingga masih memungkinkan untuk kegunaan-kegunaan lainnya dalam bidang farmasi. Kata Kunci: Tumbuhan Libo (Ficus variegata), bahan farmasi potensial ABSTRACT Libo ( Ficus varieagata ) is a wild plant that has not been utilized in any form , including traditional because it has latex plant fruit and bark , and if the latex on the skin cause itching occurs even irritation . The nature of that cause undesirable fruit so that the fruit -eating animals are well maintained . Libo ripe fruit on the tree will fall to the ground and grow into a tree Libo Libo dewasa.Potensi plant fruiting and fruit continuously disliked fruit -eating animals that populations of plants Libo maintained and continues to grow . Has conducted numerous studies on fruit Libo relation with potential pharmaceutical and proven potential as a source of antioxidant , cytotoxic or anticancer , exterminator larval A. aegypti , and as an antibacterial . These potentials can be used as a preservative , an anticancer drug , and a source of antibiotics if the research is done in detail . Libo fruit also contains a group of secondary metabolites are highly variable so it still allows for other uses - uses in the pharmaceutical field . Key Words: Tumbuhan Libo (Ficus variegata), bahan farmasi potensial
Aktivitas Antibakteri Ekstrak Daun Kecapi (Sandoricum koetjape Merr.) Hardika P.A.N, Pindo; Fridayanti, Aditya; Rijai, Laode
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (118.739 KB) | DOI: 10.25026/jtpc.v2i3.64

Abstract

A research has been conducted on the antibacterial activity of the santol leaves extract (S.koetjape Merr.) against S.aureus and E.coli. The santol leaves extracts were prepared by maceration used methanol as solvent and the methanol extract was then fractionated. The antibacterial activity was determined by measured the diameter of inhibition zones in difusi method. The result showed that santol leaves extracts and fractions has antibacterial activity against S.aureus and E.coli. The effective concentration as an antibacterial of methanol extracts is at 10%, and of n-hexane fractions is at 5%. Keywords : S.koetjape Merr, Santol leaves, Antibacteria Abstrak Telah dilakukan penelitian uji aktivitas antibakteri ekstrak daun kecapi (S.koetjape Merr.) terhadap S.aureus dan E.coli. Ekstrak daun kecapi dibuat secara maserasi dengan pelarut metanol, lalu difraksinasi. Uji aktivitas antibakteri ekstrak daun kecapi diukur berdasarkan luas daerah zoa bunuh pertumbuhan bakteri dengan metode difusi agar. Hasil uji menunjukkan bahwa ekstrak dan fraksi daun kecapi memiliki aktivitas antibakteri terhadap bakteri S.aureus dan E.coli. Konsentrasi efektif antibakteri ekstrak metanol adalah 10% dan fraksi n-heksana adalah 5%. Kata Kunci : S.koetjape Merr, Daun Kecapi, Antibakteri
Penentuan Dosis Efektif Ekstrak Daun Pacar (Lawsonia inermis L.) sebagai Antiinflamasi Megawati, Selvi; Herman, Herman; Masruhim, Muhammad Amir
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.443 KB) | DOI: 10.25026/jtpc.v2i3.65

Abstract

Has been conducted a research of dose determination of effectiveness extract of Lawsonia inermis L. as anti-inflammatory on Rattus norvegicus. The purpose of this research is to gain an in depth understanding of effective dose of Lawsonia inermis L. as anti-inflammatory toward the reduction time of swelling on Rattus norvegicus’ feet .The method which being used was carrageenan induced on Rattus norvegicus’ feet. Rattus norvegicus were devided to 6 (six) group which a group as negative control was given sodium CMC orally, a group as positive control was given Sodium Diclofenac orally, and 4 (four) as test was given extract with 4 doses variation (50mg/kg, 100mg/kg, 150 mg/kg, and 200 mg/kg) orally to each of mice that has pre-conditioned to swell on its foot. The result shows that T-Count is bigger than T-Table with significant standart 0,05 and smaller than T-Table with significant standart 0,01. It proves that there is significant difference between sodium diclofenac and extract of Lawsonia inermis L in 100mg/kgBW. That concludes that extract of Lawsonia inermis L. has anti-inflammatory effect with effective dose as anti-inflammatory in 100mg/kg. Keywords : Lawsonia inermis L., Anti-inflammatory., Rattus norvegicus. Abstrak Telah dilakukan penelitian penentuan dosis efektif ekstrak daun pacar (Lawsonia inermis L.) sebagai antiinflamasi pada tikus putih (Rattus norvegicus). Penelitian ini bertujuan untuk mengetahui dosis ekstrak daun pacar yang efektif sebagai antiinflamasi terhadap waktu penurunan bengkak pada kaki tikus putih. Metode yang digunakan yaitu induksi karagenan pada kaki tikus putih. Tikus putih dikelompokkan menjadi 6 kelompok yaitu kelompok kontrol negatif diberikan natrium CMC, kelompok kontrol positif diberikan natrium diklofenak dan 4 kelompok uji diberikan ekstrak dengan 4 variasi dosis yaitu 50 mg/kg, 100 mg/kg, 150 mg/kg dan 200 mg/kg yang masing-masing diberikan secara oral dan tiap kaki tikus dikondisikan bengkak terlebih dahulu. Hasil penelitian ini membuktikan ekstrak daun pacar memiliki kemampuan sebagai antiinflamasi dengan dosis efektif 100 mg/kgBB. Kata Kunci: Lawsonia inermis L., Antiinflamasi, Rattus norvegicus.
Team, Front cover, Editorial information, Table of Content, Back Cover
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.769 KB)

Abstract

J. Trop. Pharm. Chem. 2013. Volume 2 Nomor 3. Team, Front cover, Editorial information, Table of Content, Back Cover
Stabilitas Fisik dan Kimia Minyak Biji Ketapang (Terminalia catappa L.) Selama Penyimpanan Saputri, Delima; Fitriani, Victoria Yulita; Masruhim, Muhammad Amir
Journal of Tropical Pharmacy and Chemistry Vol. 2 No. 3 (2013): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v2i3.59

Abstract

Ketapang (Terminalia catappa L.) is each one potentialy to producting of nabati oil. The research is purposes to determine effect of storage period on room and extreme temperature of ketapang seeds oil’s physical and chemical stability. Ketapang seeds oil was getted from ketapang seeds extraction by n-hexana with soxhletasi method. Ketapang seeds oil stability evaluation on room temperature 27 – 30 °C as long as 50 days and extreme temperature 65 °C as long as 10 days. Physical stability that color, aroma, and flavor use organolepticly, pH use pH-meter, density use piknometer, and viscosity use Oswald viscometer. Chemical stability that acid value, peroxide value, and soap value by titration method, and amount of tocopherol compound by spectrometry method. The result data was analyzed with linier regretion. The analyzed result of aroma, flavor, pH, density, soap value, and tocopherol compound showed descend linier, viscosity, acid value, and peroxide value showed ascend linier, and color of ketapang seeds oil is stabil as long as storage on room and extreme temperature. Storage period on extreme temperature more significant than room temperature to effect evaluation result of ketapang seeds oil’s physical and chemical parameters. Key Words: Terminalia catappa L., Storage Period, Physical and Chemical Stability. Abstrak Ketapang (Terminalia catappa L.) merupakan salah satu tumbuhan yang berpotensi sebagai penghasil minyak nabati. Penelitian ini bertujuan untuk mengetahui pengaruh lama penyimpanan pada suhu ruang dan ekstrim terhadap stabilitas fisik dan kimia minyak biji ketapang. Minyak biji ketapang diperoleh dari ekstraksi biji ketapang dengan pelarut n-heksana menggunakan metode soxhletasi. Penentuan stabilitas fisik minyak meliputi warna, bau, dan rasa, pH, bobot jenis, dan viskositas. Penentuan stabilitas kimia meliputi penentuan angka asam, angka peroksida, dan angka penyabunan, serta kandungan tokoferol. Hasil pengujian dianalisis menggunakan regresi linier. Berdasarkan hasil analisis, disimpulkan bahwa pada parameter bau, rasa, pH, bobot jenis, angka penyabunan, dan kandungan tokoferol menunjukkan hubungan linier dengan kecenderungan turun, pengujian terhadap parameter viskositas, angka asam, dan angka peroksida menunjukkan hubungan linier dengan kecenderungan naik, sedangkan parameter warna minyak biji ketapang cenderung stabil selama penyimpanan pada suhu ruang maupun suhu ekstrim. Lama penyimpanan pada suhu ekstrim lebih signifikan mempengaruhi hasil pengujian pada parameter fisik dan kimia minyak biji ketapang dibandingkan pada suhu ruang. Kata Kunci : Terminalia catappa L., Lama Penyimpanan, Stabilitas Fisik dan Kimia.

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