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SRIWIJAYA JOURNAL OF MEDICINE
Published by Universitas Sriwijaya
ISSN : -     EISSN : 26223589     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health
Sriwijaya Journal of Medicine (SJM) is a scientific journal managed by Faculty of Medicine Universitas Sriwijaya, Indonesia. It publishes original research articles and reviews in Biomedical Sciences, Medicine (Neurology, Cardiovascular, Respiratory, Gastrointestinal, Urogenital, Endocrine and Metabolism, Integument, Mental Health, Obstetry and Gynecology, Ophtalmology, ENT, Musculosceletal) and Public Health Medicine. Sriwijaya Journal of Medicine (SMJ) published three times a year (January, April, October).
Arjuna Subject : Kedokteran - Anatomi
Articles 260 Documents
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Analisis Gen Blavim, Blandm dan Blaimp Carbapenemase dengan Alat Otomatis Vitek-2 dan Metode Polymerase Chain Reaction (PCR) pada Isolat Bakteri Enterobacteriaceae di RSUP Dr. Moh. Hoesin Palembang Sabrina, Tia; Rivani, Erizka; Patricia, Venny
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Enterobacteriaceae is a normal flora in human intestinal tract which the most frequently caused the disease in human. Carbapenem is the last lines of antibiotic which used to treat severe infection that caused by gram-negative bacili bacteria, for example Enterobacteriaceae, but there is an increase prevalency of infection which caused by Carbapenem Resistant Enterobacteriaceae (CRE). The gene that encoding CRE is blaVIM, blaNDM, and blaIMP gene. The detection of these genes are very important to prevent spreading the nosocomial infection at hospital. The samples are from the speciment which has detected as isolate of Extended Spectrum Beta Lactamase (ESBL) Enterobacteriaceae bacteria and has occurred resistant to carbapenem group (meropenem and ertapenem) which detected by automatic equipment, VITEK 2 compact system. These samples will be processed by PCR with multiplex PCR technique to indentify blaVIM, blaNDM, and blaIMP gene. There are 43 samples consist of 33 samples (76,7%) ESBL bacteria isolate and 10 samples (23,3%) Carbapenemase bacteria isolate, 29 samples (67,4%) are Klebsiella pneumonia and 14 samples (32,6%) E. coli. These samples were from blood (5 samples/ 11,6%), sputum (16 samples/ 37,2%), peritoneal fluid (1 sample/ 2,3%), pus (4 samples/ 9,3%), urine (12 samples/ 28%), swab (3 samples/ 7%), tissue (1 sample/ 2,3%), and feces (1 sample/ 2,3%). From the PCR result, the gene was indentified from Enterobacteriaceae bacteria isolate was 28 samples (65,11%) from 43 samples. The indentified samples consist of 9 samples (32,1%) Carbapenemase bacteria isolate and 19 samples (67,9%) ESBL bacteria isolate. The identified of Enterobacteriaceae bacteria isolate consist of 15 samples blaNDM gene, 17 samples blaVIM gene, and 4 sample blaIMP gene.
Hubungan Antara Anemia dan Kebiasaan Merokok pada Ibu Hamil dengan Kejadian BBLR di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2016 sari, Intan
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Low Birth Weight (LBW) is an infant born with a birth weight of less than 2500 grams regardless of gestation. Birth weight is the weight of the baby weighed in 1 hour after birth. (Depkes RI, 2009). Based on WHO and UNICEF data, in 2013 about 222 million babies were born in the world, of which 16% were born with low birth weight. The percentage of LBW in developing countries is 16.5% twice that of developed countries (7%) (Scholar Unand, 2014). The purpose of this study was to determine whether there is a relationship between anemia and Smoking Habit in Pregnant Women with LBW occurrence in General Hospital Dr. Mohammad Hoesin Palembang Year 2016. This research use analytical survey method with cross sectional approach. The population in this study were all mothers who gave birth monthly in Midwifery Installation of Dr. General Hospital Mohammad Hoesin Palembang in 2016 as many as 315 respondents. The sample of this research is some of mothers who give birth enough month in Midwifery Installation of Dr. General Hospital Mohammad Hoesin Palembang Year 2016 as many as 315 respondents. ". From the results of bivariate analysis of anemic respondents with the occurrence of LBW obtained statistical test X2 count = 23.22 which means there is a significant relationship between anemia with the incidence of BBLR. Respondents smoking with the occurrence of LBWR obtained statistical test X2 count = 41.20 which means there is a relationship Meaningful between smoking and LBW incidence. From the results of this study is expected that this research can be a reference material and is a complete information and useful for the development of knowledge about LBW.
Influence of Fe tablets to Increase Hemoglobin Levels of TB Patients in District of Seberang Ulu I Palembang City: Pengaruh Pemberian Tablet Fe Terhadap Peningkatan Kadar Hemoglobin Pasien TB di Kecamatan Seberang Ulu I Kota Palembang Novita, Emma; pariyana, Pariyana
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

People with active pulmonary TB are often macronutrient deficiencies, weight loss and decreased appetite. TB patients are susceptible to anemia, with Fe tablets given is able to cure low TB hemoglobin levels. The method of this study was conducted with the design of Quasi Experimental study. The population was tuberculosis patients in Seberang Ulu I District, with 25 sample of positive TB patients. Samples were given Fe tablet for 90 days. The results of this study were given Fe tablet tablets that affected significant hemoglobin levels (P <0.002) between patients before was before and after tablets were given. The increment of hemoglobin levels of patients before and after the end of tablet given of TB patients was 1.16 g / dl. Suggestions that can be given is the need to be given Fe tablets in TB patients to improve nutritional status so that treatment can achieve optimal results.
Prevalence of CYP2C19 Gene Polymorphism and Its Influence In Omeprazole Metabolism As Predictors Of Drug Inoxification In Malay Ethnic In South Sumatra: Prevalensi Polimorfisme Gen CYP2C19 dan Pengaruhnya Dalam Metabolisme Omeprazole Sebagai Prediktor Intoksikasi Obat Pada Etnis Melayu Di Sumatera Selatan Triwani, Triwani; Hayati, Lusia
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Cytochrome P450 2C19 (CYP2C19) is an enzyme complex that plays a role in the metabolism of several drugs and is part of the super family of cytochrome P450. Genetic polymorphisms in these enzymes are associated with the emergence of poor metabolic phenotypes (poor metabolizers / PMs and intermediate metabolizers / IMs) that have a poor ability to metabolize the drugs that become substrates. Genotypes and phenotypes were analyzed using PCR-RFLP and bio-analysis of omeprazole levels in 30 subjects from ethnic Malay living in South Sumatra. Markers used to assess the presence of polymorphisms in the CYP2C19 gene are two polymorphic sites of exon 5 (CYP2C19 * 2) and exon 4 (CYP2C19 * 3). 321 bp DNA bands for exon 5 and 271 bp for exon 4 will be produced after DNA amplification by PCR method under denaturation for 5 min at 95oC; followed by 60 seconds at 95oC, 60sec at 53oC and 60sec at 72oC for 30 cycles; as well as the final polymerization for 5 minutes at 72 ° C. Furthermore, DNA cutting was done using the restriction enzyme endonuclease SmaI (CYP2C19 * 2) at 30oC and BamHI (CYP2C19 * 3) with incubation at 37oC for 3 hours. Bioanalysis of omeprazole levels in the blood with LC-MS. The results of this study indicate the presence of polymorphisms on both sites will eliminate the enzyme sites SmaI and BamHI. The results showed that 46.7% of South Sumatran Malay populations were classified as PM consisting of 13.3% homozygous mutandan mutant 33.4% heterozygotes. The high phenotype of PM enzyme CYP2C19 in ethnic Malays in South Sumatra predicted to influence metabolism of drugs become substrates. However, based on spearman correlation analysis, the correlation value was 0.035 with p = 0.875. This means that between the CYP2C19 gene polymorphism and the omeprazole levels in the blood there is a weak and meaningless correlation. The results of this study provide an overview of the high genetic polymorphisms of dyspepsia syndrome patients from the Malay population, ie almost half of the study subjects (46.7%). There is a weak and insignificant correlation between polymorphism and omeprazole levels.
Evaluation of Running Speed and Distance Throwing After Doing Needle Intervention (Dry Needling) at Sriwijaya Sports Students Palembang: Evaluasi Kecepatan Lari dan Jarak Lempar Setelah Dilakukan Intervensi Tusuk Jarum (Dry Needling) pada Siswa Olahraga Sriwijaya Palembang Septadina, Indri Seta; Suciati, Tri; Adnindya, Msy Rulan
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

The factor supporting the achievement sports is physical skill consisting of speed, the power, agility, coordination and time reaction. Performance of speed determined by motion of the body as the arm and limbs that consisting of components such as muscle, bone, joints, vascularisation and innervation..Stimulation on nerve can improve the ability muscle then it can increasing the physical skill. The method often used is electric stimulator and dry needling. The purpose of this research is to assess running speed and throwing distance through intervention a dry needling to 35 students of Sriwijaya Sport High School Class XII with one group pretest and posttest design.The result showed average of running speed before dry needling is 7,48 ± 0,94 and after dry neddling is 7,44 ± 0,70. However statistical tests using the test paired t get p value = 0,679 (α =0,05 (p>α).The measurement result of throwing distance before dry neddling is 15,61 ± 8,54 and after dry needling is 16,35 ± 8,90. Wilcoxon test shows that p value = 0,077 (α =0,05 (p>α). The result showed that there is no difference between speed run and distance throwing before and after conducted a needle intervention dry ( dry needling ).
Comparative Effectiveness of Papaya Leaf Stew (Carica Papaya Linn) With Turmeric Acid (Curcuma Domestica Val-Tamarindus Indica) Against Primary Dysmenorrhea: Perbandingan Efektifitas Rebusan Daun Pepaya (Carica Pepaya Linn) Dengan Kunyit Asam (Curcuma Domestica Val-Tamarindus Indica) Terhadap Dismenore Primer Liana, Yunita
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Young women often feel primary dysmenorrhoea because the hormonal cycles experienced are not stable, this can disrupt the concentration and activity of young women. The principle of back to nature is increasingly popular today, the side effects of chemical drugs can cause new problems, it is one of the driving force of the development of traditional medicine. Papaya leaves contain Vitamin E which can reduce dysmenorrhea. In addition, turmeric acids also contain curcumine and anthocyanins that inhibit cyclooxygenase, thereby reducing the occurrence of inflammation during uterine contractions. The aim of this research is to know the effectiveness of papaya leaf stew with acidic turmeric to primary dysmenorrhea. Type of Research is an experimental study with a Pretest-Posttest Control Group Design design. The sample is 30 people. The research was conducted on December 27, 2017 s.d February 24, 2018 at SMP Negeri 46 Palembang. Instrument to measure pain Numeric Rating Scale. The statistical test used by Wilcoxon and Mann Whitney U. Average score of pain before papaya leaves stem 5.40 ± 0.73 while the mean score of pain after given turmeric acid 5.33 ± 0.61 The mean score of pain after being given papaya leaves stew 3.60 ± 0.91 while the mean score of pain after given turmeric acid 4.06 ± 0.79. There was a difference of mean score of dysmenorrhea pain before and after given papaya leaf stem p value = 0.000. There is difference of mean score of dysmenorrhea pain before and after given turmeric acid p value = 0,002. There was no difference of mean score of dysmenorrhea pain before and after given papaya leaf sting and turmeric acid p value = 0,217. The decoction of papaya leaf and turmeric acid have the same effectiveness in reducing primary dysmenorrhea pain.
Association of Mother’s Knowledge About Breast Milk nnd Breastfeeding With Exclusive Breastfeeding in Kecamatan Ilir Timur II Palembang.: Hubungan Pengetahuan Ibu Mengenai ASI dan Menyusui dengan Pemberian ASI Eksklusif di Kecamatan Ilir Timur II Palembang Lestari, Puji; Kurniati, Ardesy meilizah; Mamun, Asmarani
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Exclusive breasfeeding is defined as giving breast milk for infants from birth tosix months of age. The percentage of exclusive breastfeeding in Palembang hasnot reached national target. There aremany factors that may affect the mother in exclusive breastfeeding, one of which is mother's knowledge of breast milkand breastfeeding. The aim of this study was to examine the association of mother’s knowledge about breast milkandbreastfeeding with exclusive breastfeeding in Kecamatan Ilir Timur II Palembang. This cross-sectional study was held inJuly–December 2016. The population of this studywere mothers who have baby 6–24 months age in PuskesmasKecamatan Ilir Timur II. In this study, there were 93 mothers who fulfill inclusion criteria. The data were taken fromstructural interview by using questionnaire. The data were analyzed by Chi-Square statistic test using IBM SPSS Statistic22. The was no significant association of mother’s knowledge about breast milk and breastfeeding with exclusivebreastfeeding (p=0,120). The mother’s knowledge about breast milk and breastfeeding was not related with exclusivebreastfeeding in Kecamatan Ilir Timur II Kota Palembang.
Benign Tumor in Labia Minora Putra, Hadrians Kesuma; Anggraeni, Asih; rinaldi, andi; moegni, fernandi
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Vulva tumors are generally a rare disease encountered in gynecological clinical practice, especially at a young age. Vulvar tumors, more common in the labia major and rarely in the labia minor, clitoris, vestibulum, and posterior comicura. The most common vulvar benign tumors are fibroma, papilloma, lipoma, angioma, and others. A 39-year-old woman, at RSCM Urogynecology Jakarta clinic with chief complain mass or swelling in right labia minor. Size of mass increases in period of one year. Mass began to grow at 8 months of pregnancy. By 2014, patients have same mass in the right and left labia minor, and tumor excision has been performed. Conclusions of the specimens sent for pathological assessment are fibroepithelial papillomas. Gynecological and palpation examinations show 2 solid papilloma masses, in right labia minor, 8x4x2 cm and 3x2x2cm, painless, and firmly defined. In mons pubis area, skin looks coarse, thickened, hyperkeratotic. Speculum examination showed no abnormality. Patient diagnosed as a recurrent minor armored labia tumor. On December 5, 2017 an excision and reconstruction operation was conducted. Obtained pathological exam on December 20, 2017 with results stromal fibroepithelial polyps. Among all tumors in the vulva, tumors in labia minor appear less frequently. Biopsy should be performed for histologic examination to exclude malignant allegations. Furthermore, because of the location and size of the tumor, it can cause severe interference symptoms in the patient and therefore early diagnosis and treatment is essential.
Prevalensi Kejadian Penyakit Menular Seksual (HIV, Hepatitis B, Hepatitis C, dan Sifilis) pada Wanita Penjaja Seks di Palembang Liana, Phey; Patricia, Venny; Ieawi, Catherine; Ienawi, Calvin
Sriwijaya Journal of Medicine Vol. 1 No. 2 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Data Centers for Disease Control and Prevention (CDC) tahun 2016 menunjukkan sekitar 110 juta orang menderita penyakit menular seksual (PMS). PMS sering kali dipandang sebelah mata, padahal dampaknya bagi kesehatan jangka panjang cukup signifikan terutama pada wanita dan bayi, seperti infertilitas, kelainan kongenital, kanker dan lain-lain. Penjaja seksual merupakan kelompok berisiko tinggi untuk tertular PMS. Karena itu, perlu diketahui prevalensi PMS terutama pada mereka yang berisiko tinggi (wanita penjaja seksual) sehingga dapat dibuat kebijakan terkait program pengendalian dan pencegahan PMS. Jenis penelitian yang digunakan adalah studi prevalensi dengan pendekatan survai klinis secara cross sectional. PMS yang dihitung prevalensinya pada penelitian ini adalah infeksi HIV, Hepatitis B, Hepatitis C dan sifilis. Serum dari subjek penelitian dikumpulkan dan diperiksa anti-HIV untuk infeksi HIV, anti-HCV untuk Hepatitis C, HbsAg untuk Hepatitis B dan VDRL untuk sifilis. Didapatkan prevalensi PMS pada wanita penjaja seksual di Palembang adalah sebagai berikut yaitu: HIV sebesar 4.9%, sifilis sebesar 3.3%, Hepatitis B sebesar 9.8% dan Hepatitis C sebesar 1.6%. Edukasi, sosialisasi terkait bahaya dan dampak dari PMS perlu dilakukan terutama pada mereka yang berisiko tinggi seperti pada wanita penjaja seksual sebagai bentuk dari program pengendalian dan pencegahan PMS.
Parental Risk Factors in Children With Intellectual Disability: An Investigation.: Faktor Risiko Orang Tua Pada Penyandang Disabilitas Intelektual (DI) di Sekolah Luar Biasa (SLB) Palembang Maritska, Ziske; Arroyantri, Bintang
Sriwijaya Journal of Medicine Vol. 1 No. 1 (2018): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Intellectual Disability (ID) is a condition where there is a significant disturbance in one’s development including social, cognitive and adaptive function. The prevalence of ID worldwide is varied, whereas its prevalence in South East Asia including Indonesia is quite high. The exact cause of ID is yet to be known. A couple of risk factors are believed to be involved in the occurence of ID. This study aims to identify parental risk factors in children with ID in Special Need School in Palembang. This is a observational descriptive study towards children with ID in Special Need School in Palembang. Primary data were obtained from direct interview and questionnaire filled by parents. Variables being identified were Paternal risk factors (age and smoking habit), Maternal risk factors (age, parity, drug and herbs consumption history during pregnancy, smoking exposure during pregnancy) and family history. There are 68 samples who are mostly male (64.70%) with Mild ID (60.29%). Majority of the Father were <35 years old when they had their child (64.71%) with a smoking habit of 52.94%. Most Mother were age 21-35 years old when pregnant, with parity history of less than 4 (77.94%). Children with ID in Special Need School Palembang showed similar risk factors compared to previous studies. It is hoped that the prevalence of ID can be reduced by preventing the known risk factors.

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