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INDONESIA
Jurnal Respirasi (JR)
Published by Universitas Airlangga
ISSN : 24070831     EISSN : 26218372     DOI : -
Core Subject : Health,
Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.
Arjuna Subject : -
Articles 231 Documents
The Correlation of Rapid Antibody Results with SARS-CoV-2 PCR in COVID-19 Patients in Ulin General Hospital Banjarmasin Isa Ansori; Soraya Riefani; Ira Nurrasyidah
Jurnal Respirasi Vol. 7 No. 3 (2021): September 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.435 KB) | DOI: 10.20473/jr.v7-I.3.2021.100-105

Abstract

Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of clinical disease, better known as COVID-19. The most common method to detect COVID-19 is serological testing of IgM and IgG in response to viral infections using rapid diagnostic test (RDT). Several other guidelines consider polymerase chain reaction (PCR) as the gold standard for diagnosis becausePCR has high sensitivity and specificity values in detecting SARS-CoV-2.Methods: This was a descriptive analytical study. The samples were taken from medical records of COVID-19 patients in Ulin General Hospital Banjarmasin from March to October 2020. Statistical Package for the Social Sciences (SPSS) 16.0 software and Chi-Square test were used for data analysis.Results: From 751 COVID-19 patients, 408 patients (54.32%) had rapid antibody with positive PCR, 132 patients (17.57%) had reactive rapid antibody with negative PCR, 152 patients (20.23%) had non-reactive rapid antibody with positive PCR, and 59 patients (7.85%) had non-reactive rapid antibody with negative PCR. The rapid antibody had sensitivity of 72.85% and specificity of 30.89%. From Chi-Square test, reactive rapid antibody was not correlated with PCR positive results; values of p = 0.320, odds ratio (OR) 1.20.Conclusion: The rapid test antibody could not be recommended as a diagnostic tool. In this study, it was also found that there was no relationship between reactive rapid test results and positive SARS-CoV PCR.
Exhaled Carbon Monoxide Levels of Scavengers in Bantar Gebang Landfill, Bekasi Agus Dwi Susanto; Dita Kurnia Sanie; Fahrial Harahap
Jurnal Respirasi Vol. 6 No. 1 (2020): January 2020
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.057 KB) | DOI: 10.20473/jr.v6-I.1.2020.1-4

Abstract

Background: Scavengers in landfills have high risk to pollution exposure. Carbon monoxide (CO) is one of important pollutants produced by burning process. Exhaled CO levels in scavengers is predicted to increase, caused by pollution exposure in workplace area. There has been no data on exhaled CO levels in scavengers, especially in Bantar Gebang, Bekasi.Methods: This study used cross-sectional design to the scavengers who work and live in Ciketing Udik, Bantar Gebang, Bekasi. This study was conducted in January - March 2015, by doing interviews and giving questionnaires, and conducted exhaled CO test.Results: Total sample was 108 subjects. Exhaled CO test result was 46 subjects (42.6%) had exhaled CO 5-10 ppm, 36 subjects (33.3%) > 10 ppm, and 26 subjects (24.1%) ≤ 4 ppm. Multivariate analysis between exhaled CO levels with characteristics of the subjects found smoking habits were significantly correlated with CO exhalation levels (p=0,000).Conclusion: There were 33.3% scavengers who had exhaled CO > 10 ppm. Smoking habits were the only factor that significantly correlated with CO in scavengers’ exhalation.
Management of Cough Arief Bakhtiar; Putri Mega Juwita
Jurnal Respirasi Vol. 6 No. 3 (2020): September 2020
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.072 KB) | DOI: 10.20473/jr.v6-I.3.2020.85-96

Abstract

Cough is the most frequent symptom for which patients consult with their health care provider throughout the world. This symptom could be happened not only in sick individuals but also healthy individuals. At some stage, it is distressing, inhibits normal social activities, and reduces quality of life. Besides these detrimental effects, cough is the most effective defense mechanism to eliminate foreign materials, including various pathogens, from the respiratory tract. It begins with a series of breathing maneuvers which triggers sudden expulsion of air which is divided into three phases, i.e. inspiration, compression, and expiration phase. Cough occurs due to activation of mechanical or chemical sensory receptors in the larynx and lower respiratory tract which stimulates reflex arc complex. This stimulus is then transmitted to the afferent pathway to the cough center in the medulla through the vagus nerve to trigger expiration muscles to produce cough. It is important to know the cause of cough because cough is an indicator for patients and doctors for early diagnosis and therapy of disease. Therefore, cough is classified into acute, subacute, and chronic according to its duration. Available medications for symptomatic management of cough are inadequate due to lack of proven efficacy and/or their undesirable or intolerable side effects. This article aims to provide information on cough management to improve therapeutic effectiveness and patient quality of life.
Front Matter Vol 4 No 3, 2018 Front Matter
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.139 KB) | DOI: 10.20473/jr.v4-I.3.2018.%p

Abstract

Front Matter Vol 6 No 3, 2020 Front Matter
Jurnal Respirasi Vol. 6 No. 3 (2020): September 2020
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.338 KB) | DOI: 10.20473/jr.v6-I.3.2020.%p

Abstract

Pemphigus Paraneoplastik pada Timoma : [Pemphigus Paraneoplastic in Thymoma: A Rare Case] Herley Windo Setiawan; Daniel Maranatha
Jurnal Respirasi Vol. 4 No. 1 (2018): Januari 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (645.973 KB) | DOI: 10.20473/jr.v4-I.1.2018.5-11

Abstract

Thymomas are mediastinal primary tumour of the mediastinum and associated with a variety of autoimmune disorders often linked to T-cell mediated autoimmunity. Paraneoplastic pemphigus (PNP) is an immunologically mediated skin disease characterized by epidermal blisters that may occur in association with thymic or non thymic neoplasms. Case: 21 years old man came to the hospital with vesicles and ulcer in oral cavity and extended to whole body since 3 weeks before. Patient was diagnosed with Pemphigus vulgaris and thymomas since 2 years. Patient was hospitalized for 3 times with same cases. Patient underwent chemotherapy Carboplatin-Etoposide 6 series and Radiotherapy 25 series and no response had been documented. Patient was suggested to undergo a resection of thymoma to prevent the exacerbation of pemphigus but he refused. The medication given was only aimed for reducing the exacerbation of Pemphigus. Discussion: PNP is characterized by the production of autoantibodies against various target antigens, mainly plakin family proteins and desmogleins. PNP results from an antitumor immune response cross-reacting with the normal epithelial proteins and thereby inducing autoimmunity by molecular mimicry. PNP sera bind to homologous region within carboxyterminus of members of the plakin gene family. There are also involvement of dysregulation of T-cell development. Conclusion: Pemphigus is rarely associated with Thymomas, but the fact there is an association between Thymomas and pemphigus. According to this fact, every patients with pemphigus should be suspected with malignancies especially thymomas until it was ruled out.
Peran Steroid pada Pneumocystis Pneumonia Ditinjau Berdasarkan Imunopatogenesis : [Immunopathogenesis of Steroid in Pneumocystis Pneumonia] Resti Yudhawati; Whendy Wijaksono
Jurnal Respirasi Vol. 5 No. 2 (2019): Mei 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (668.45 KB) | DOI: 10.20473/jr.v5-I.2.2019.57-64

Abstract

Pneumocystis Pneumonia (PCP) is a potentially life-threatening infection that can occur in individuals who are immunocompromised. In PCP steroid use is still recommended especially in patients with moderate and severe severity. Corticosteroids are given along with anti-pneumocystis therapy and are known to reduce the incidence of mortality and respiratory failure associated with PCP. Innate immunity and adaptive immunity are symbiotic relationships to provide optimal defense for the lungs and other organs and tissues from infection PCP. The corticosteroid mechanism in PCP is based on an anti-inflammatory mechanism especially its role in inhibiting neutrophils. Many clinicians believe the administration of anti-pneumocystis causes the acceleration of inflammation. Because the inflammatory process increases when anti-pneumocystis therapy is started, corticosteroid therapy is useful before inflammation occurs which causes extensive damage to the lungs.
Front Matter Vol 3 No 2, 2017 Front Matter
Jurnal Respirasi Vol. 3 No. 2 (2017): Mei 2017
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (631.463 KB) | DOI: 10.20473/jr.v3-I.2.2017.%p

Abstract

Peranan Ultrasonografi Toraks dalam Menegakkan Diagnosis Beberapa Kelainan pada Paru: [The Role of Ultrasound in Diagnosing Pulmonary Diseases] Erwin Winaya; Winariani Koesoemoprodjo
Jurnal Respirasi Vol. 1 No. 1 (2015): Januari 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (733.611 KB) | DOI: 10.20473/jr.v1-I.1.2015.29-39

Abstract

Ultrasound is useful in the diagnosis of cases in the field of lung disease, such as pleural effusion, pneumothorax, consolidation, atelectasis, pulmonary edema, and others. The advantages of thoracic ultrasound is a low cost, radiation is small, easy to carry, short examination time and has a dynamic aspect that can be seen at the time of examination. Thoracic ultrasound is an inexpensive tool and can be used to assist in intervention, especially in cases of peripheral lung, pleura and chest wall diseases, such as thoracocentesis, chest tube installation and aspiration lung abscess. Ultrasound can also replace aspiration and biopsy with CT-scan guidance in cases involving the pleura, chest wall, and lung tumors that invade the pleura and chest wall. With the ultrasound portable and compact form, in the future is possible if the ultrasound will be a routine part of the examination as well as a stethoscope. However, ultrasound also has limitations which in patients with subcutaneous emphysema, peripheral edema and obesity, lung ultrasound is hard to do. Ultrasound examination is also highly dependent on the experience and ability of the ultrasound operator.
Clinical Microbiology Perspective of Empyema caused by Streptococcus constellatus in Malignancy Patient: A Case Report Agung Dewi Sekar; Rosantia Sarassari; Soedarsono Soedarsono; Kuntaman Kuntaman
Jurnal Respirasi Vol. 7 No. 2 (2021): May 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.936 KB) | DOI: 10.20473/jr.v7-I.2.2021.75-78

Abstract

Introduction: Streptococcus constellatus (SC) is commensal bacteria and belongs to Streptococcus anginosus group (SAG). However, SC causes infections especially in patient with underlying diseases. SC empyema is a clinical case that is described in very few studies, especially in Indonesia.Case: A 45-year-old man was admitted to emergency department in Dr. Soetomo General Hospital Surabaya with respiratory insufficiency on November 11th 2020 after 3 months of non-productive cough and a week of weakness. He was diagnosed with empyema on right hemithorax and received chest tube insertion. SC was isolated from pleural fluid sample after first day of culture on Bactec BD bottle. GeneXpert result of pleural fluid was negative for Mycobacterium tuberculosis (MTB). He completed 10 days of intravenous ampicillin-sulbactam and metronidazole. The CT scan reported solid mass of 4.7x7.4x7.8 cm in posterolateral segment of inferior lobe right lung, right pleural effusion, with adenocarcinoma as biopsy result.Discussion: SC is a normal commensal in respiratory tract, however with the presence of a certain factor such as immunocompromised, colonized SAG directly induces an infection after entering normal sterile sites in the body including pleural fluid.Conclusion: Although infection caused by SC is a rare case, it still should be considered in clinical diagnosis and treatment of related infections, particularly in patients with comorbidities. The prognosis was good with appropriate antibiotics and chest tube insertion.

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