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Jurnal Farmamedika (Pharmamedica Journal)

farmamedika
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Published by Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

ISSN : 25026011 EISSN : 26864487 DOI : https://doi.org/10.47219/ath

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Jurnal Farmamedika dikelola oleh Lembag Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Teknologi Industri dan Farmasi Bogor. Frekuensi penerbitan jurnal sebanyak 2 kali dalam satu tahun pada bulan Juni dan Desember. Kategori tulisan berupa hasil penelitian dari peneliti maupun akademisi dalam bidang Kimia Bahan Alam, Analisis Farmasi, Farmakologi dan Toksikologi, Kimia Medicinal, Biologi Molekular dan Bioteknologi, Farmakoterapi, Farmasi Klinis, Farmasetika dan Teknologi Farmasi, Biologi Farmasi, Manajemen Farmasi, Farmakoekonomi.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 94 Documents

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PENENTUAN KADAR KAFEIN KOPI ROBUSTA TERFERMENTASIOLEH Enterococcus durans, Enterococcus sulfureus, DAN Lactococcus garvieae Sitaresmi Yuningtyas; Syahid Pratama Al-Wali; Winugroho
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 2 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Many people like to drink coffee because it has a unique flavor. Coffee also containscaffeine,which is not good for health. One of the most famous type of coffee is civet coffee (kopi luwak).This coffee is unique because lower caffeine and in the process of this coffee should be consumedfirst by civet. The issue is populations of civet who began to decrease and the process that makes itdifficult to be produced on a large scale in a short time. In this research, we tried to apply culture ofEnterococcus durans, Enterococcus sulfureus, and Lactococcusgarviea for processing robustacoffee that resembles the civet coffee. This study aims to determine the caffeine content offermented of robusta coffee and the results will be compared with the civet coffee. Bacteria foundin the digestive system of civet had isolated and added in fermentation process of robusta coffee.Caffeine levels measured by HPLC.From these results it can be concluded that the caffeine contentin fermented of robusta coffee whichfermented using bacterial suspension Enterococcus durans,Enterococcus sulfureus andLactococcusgarvieaehad not been able to equal the caffeine content incivet coffee.Amount of caffeine in fermented of robusta coffee had lower than amount of caffeinein robusta coffee. Percentage of caffeine in fermented of robusta coffee, robusta coffee, and civetcoffeewere 1,20%, 1,90%, and 0,59% respectively.

PENGARUH PERBANDINGAN SURFAKTAN DAN KO-SURFAKTAN TERHADAP KARAKTERISTIK DAN KESTABILAN MIKROEMULSI MINYAK ZAITUN (Olive oil) Devi Ratnasari; Harry Noviardi; Baiq Annisa Apriyanti A.R
Jurnal Farmamedika (Pharmamedika Journal) Vol 2 No 2 (2017): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Olive oil is a compound known to have pharmacology activity, such as anticolesterol. Low solubility of olive oil lead to become low bioavailabilitas when given orally. Olive oil need to be formulations that could improve soulubility by making microemulsion. Microemulsion is an emulsion of oil in water (o/w) or water in oil (w/o) stable thermodynamically globul-size 0,1-1 μm. Type emulsion suitable for olive oil is oil in water (o/w) because it is intended for oral consumption. This research aimed to determine the comparison of the composition of the mixture of surfactants and co-surfactants in manufacture of microemulsi as well as test the stability. Microemulsion created by using tween 80 as surfactants and sorbitol as co-surfactants with a comparison of surfactants and co-surfactant (1:1, 2:1, 3:1, 4:1, 5:1). Microemulsion formed then evaluated organoleptis, types of density, size of globul, surface tension, viscosity and centrifugation. Evaluation results indicate the composition of surfactants and co-surfactants (5:1) has a size of globul (1,71 μm) and most low surface tension (40,8507 dyne/cm). Test of stability during 8 weeks at low, room, and high temperatures with parameter that was organoleptic, pH and viscosity. Stability test results shows that changes of pH and viscosity.

EVALUASI WAKTU TUNGGU PELAYANAN RESEP RACIKAN POLI SPESIALIS ANAK PASIEN BPJS DI RUMAH SAKIT MEDIKA DRAMAGA BOGOR Muhammad Afqary; Dewi Wiyanti; Inda Firliah
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 2 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Pharmacy services are one of the health services in hospitals that are expected to meet minimum service standards. So that one way to meet minimum service standards is to adjust the accuracy of pharmaceutical services with minimum service standards set by the government. The waiting time for concoction services is the time for patients to submit their prescriptions to receive concoction drugs with a minimum standard set of ≤ 60 minutes. The purpose of this study was to find out the factors that caused the length of prescription services for BPJS poly pediatric concoctions at the Medika Dramaga Hospital, Bogor. This research is a survey research using a quantitative approach and supported by qualitative. The results showed that the average waiting time for concoction prescription services at the Dramaga Medika Hospital in Bogor with a sample of 134 sheets of pediatrician's prescription concoction of 62.29 minutes consisted of: powder, capsules, syrup and ointment. This has not fulfilled the Decree of the Minister of Health No.129 / Menkes / SK / II / 2008.

HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT DENGAN TEKANAN DARAH PADA PASIEN HIPERTENSI DI KELOMPOK PENGELOLAAN PENYAKIT KRONIS (PROLANIS) KLINIK QITA Ferry Effendi; Elis Tiahesara; Debi Rizki Azana
Jurnal Farmamedika (Pharmamedika Journal) Vol 3 No 2 (2018): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Hypertension is widely known for its cardiovascular disease in which sufferers have blood pressure above normal blood pressure, precisely where systolic blood pressure ≥ 140 mmHg and diastolic pressure ≥ 90 mmHg measured in calm at two measurements. Compliance to medication of hypertension contributes greatly to the stability of the blood pressure. One of the efforts made to improve compliance with medication of hypertension with the chronic disease management program (Prolanis). This research aims to know the relationship of the level of compliance of taking the drug with blood pressure in patients of hypertension in chronic disease management group (Prolanis) Qita Clinic. This research use analytic research method to approach cross-sectional, in the study sample is determined by the method of purposive. This research instrument is the questionnaire MMAS-8 (Morisky Medication Adherence Scale-8) and 1 set of tools tensimeter. From the results of the research showed that respondents with high compliance as much as 14 respondents (46.7%), compliance are as many as 5 respondents (15.7%) and low compliance as much as 11 respondents (36.7%). Correlation of test results of these studies showed a relationship with medication compliance systolic blood pressure with a p value of 0.05 signifies < 0.038 and there is a connection with diastolic blood pressure with a p value of 0.05 signifies < 0.024.

ANALISIS STABILITAS LOTION MENGGUNAKAN EMULSIFIER HASIL PENYABUNAN MINYAK DAN ALKALI Armi Wulanawati; Chelsea Epriyani; Elline Sutanto
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 1 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

The lotion is one of the solid dispersion emulsion products with suitable emulsifiers. Lotion is included in cosmetics (personal care) which is usually used to moisturize, soften, and soften the skin. Types of emulsions in personal care are oil in water (o/w) emulsions which tend to be polar in nature. Emulsifiers that are often used in lotion making are emulsifiers that are formed using the saponification method of paraffin oil and triethanolamine alkali. The stability of this emulsion can be influenced by pH and viscosity (polarity) values. Emulsions that have a similar degree of polarity to oil, will tend to be stable. It is known, paraffin has a low polarity, while some other types of oils such as 2-Ethylhexyl Palmitate, Dicaprilyl Ether, Cocoglycerides, Octyldodecanol have a higher polarity, whereas some types of alkalis such as KOH flakes, AMP 95, AMP Ultra PC 3000, Tris Amino Ultra and Neutrol TE have a higher pH than Triethanolamine. Based on these things, the emulsifier in the lotion was formed by reacting stearic acid in various types of oils and alkalis which had higher polarity and pH values than the previous use of oils and alkalis. Mixing between the oil and alkaline phases is carried out at 70−75ºC to facilitate the emulsification process. The results obtained from the lotion emulsion stability test showed that the lotions in all types of oils and alkalis were stable at storage temperatures (room temperature, 45ºC, and 50ºC), and the pH was in the range of 6.75–7.60, but the best lotion emulsions and standards SNI 16-4399-1996 is using an emulsifier composed of Neutrol TE alkali and Octyldodecanol oil which has pH value 6.76-7.03, and viscosity 35000-43000 cP.

ANALISIS AKTIVITAS ANTIBAKTERI SEDIAAN GEL EKSTRAK ETANOL 70% DAUN KEMANGI (Ocimum americanumL.) TERHADAP BAKTERI Propionibacterium acnes Triyani Sumiati; Eem Masaenah; Lydia Asriyani
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 1 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Acne is skin disease caused due to a blockage of the oil gland channel and infection by the bacteria Propionibacterium acnes. Ethanol extract of 70% basil leaves has been known to be potent as antibacterial to Propionibacterium acnes. This study aims to determine the physical quality of gel preparation and antibacterial activity analysis of gel ethanol extract preparation of 70% basil leaves (Ocimum americanum L.) to Propionibacterium acnes bacteria. In this research, ethanol extract 70% of basil leaf is formulated into gel preparation form with various concentration of extract that is 45%, 55%, and 55% then in physical quality test include: organoleptic test, pH, spreading, and viscosity. The gel preparation was then analysed for its antibacterial activity using the diffusion method for the wells. Based on ethanol extract research, 70% of basil leaves had antibacterial activity with drag zone diameter of 5,20 mm (45% extract concentration), 6,06 mm (concentration of extract 50%) and 7,13 mm (concentration of extract 55%). In this study can be concluded that the higher concentration of ethanol extract 70% basil leaves the higher the inhibit zone diameter.

AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 70% DAN INFUSA DAUN KECIPIR (Psophocarpus tetragonolobus (L.) DC.) DENGAN METODE PERENDAMAN RADIKAL BEBAS Eem Masaenah; Anna Priangani Roswiem; Devina Putri
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 1 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Winged leaf (Psophocarpus tetragonolobus (L.) DC.) has been known to contain vitamin C compounds which can be efficacious as antioxidants. The aims of this study was determine the secondary metabolites contained in 70% ethanol extract and winged leaf (Psophocarpus tetragonolobus (L.) DC) infusion and to test the antioxidant activity of 70% ethanol extract and winged leaf infusion (Psophocarpus tetragonolobus (L.) DC). ) with the free radical reduction method using DPPH. Ethanol extract of 70% winged leaf (Psophocarpus tetragonolobus (L.) DC.) was made with a series of concentrations of 10, 15, 20, 25, 30 ppm and infusion of winged leaf (Psophocarpus tetragonolobus (L.) DC) with a series of concentrations of 75, 100, 125, 150, 175 ppm are both dissolved with methanol pro analysis and DPPH, then their absorbance is measured using a UV-Vis spectrophotometer at a wavelength of 517 nm. Ethanol extract of 70% winged leaf (Psophocarpus tetragonolobus (L.) DC.) Contains flavonoid, saponin, tannin, steroids and winged leaf infusion (Psophocarpus tetragonolobus (L.) DC) contains flavonoid, saponin, tannin. Ethanol extract of 70% winged leaf (Psophocarpus tetragonolobus (L.) DC.) Has antioxidant activity with IC50 value of 22.12 ppm (very strong) and winged leaf infusion (Psophocarpus tetragonolobus (L.) DC.) of 167.03 ppm (weak) and vitamin C as a positive control of 6.82 ppm (very strong).

PERBANDINGAN PENURUNAN TEKANAN DARAH PASIEN BEDAH FRAKTUR DENGAN PREMEDIKASI ANESTESI PETIDIN DAN FENTANIL DI RSUD KOTA BOGOR Siti Mariam; Kiki Fitriana Dewi; Halimatussa’diyah
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 1 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Premedication of intravenous anesthesia using the drugs petidine and fentanyl causes side effects of hypoventilation or decreased tidal volume and hypotension. This study aims to determine the decrease in blood pressure in fracture surgery patients at RSUD Kota Bogor. This study was conducted on 100 inpatients in the January-December 2018 period who were given the drugs petidine and fentanyl premedication. This type of non-experimental research with the retrospective data collection, research data were analyzed using the Kolmogorov-Sminorv test and the Mann Whitney test. Data taken included: Medical record number, age, sex, duration of surgery and blood pressure 5 minutes before premedication to 1 hour of surgery. The results found more surgical fracture patients occur in men (63%) with an age range of 40-50 years (29%). The duration of the most operations was 1 hour (62%). The most widely used premedication therapy as a narcotic analgesic drug is fentanyl (70%). The most common decrease in blood pressure is petidine (13.93 mmHg) compared to fentanyl (8.34 mm / Hg). Based on statistical results using the Kolmograv-Smirnov test and the Mann-Whitey test p-value (asymp sig. (2-tailed) showed a p-value of 0.05 (0,000) which means that there is a difference in blood pressure reduction between petidine and fentanyl.

OPTIMASI WAKTU MASERASI SILDENAFIL SITRAT DALAM JAMU KUAT YANG BEREDAR DI BOGOR BARAT Harry Noviardi; Bina Lohita Sari; Muhamad Wildan Malik
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 2 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Herbal medicine is types traditional medicine that is consumed by people. One type of herbal medicine on the market is Jamu Kuat. According Indonesian Food and Drug Administration, herbal medicine can not contain chemical of drugs. But, Jamu Kuat on the market still found contain chemical of drug, that is sildenafil citrate. In previous research, analysis of sildenafil citrate in the Jamu Kuat has not been accompained by the optimization of extraction time.The aim of research is optimizing the time of maceration sildenafil citrate in Jamu Kuat circulating on the West Bogor. Sampling of Jamu kuat was used purpusive sampling. The sample macerated with constant stirring was used a magnetic stirrer with 560 rpm and analyzis with Thin Layer Chromatography and Spectrophotometry UV-Vis method. Results of the research show that there was 5 from 8 samples Jamu Kuat contained sildenafil citrate. Optimum times of maceration was 60-90 minutes in four samples, 120-150 minutes in one sample and contains sildenafil citrate 8.00-11.00% in four samples and 20.00-21.00% in one sample. The results was concluded there different optimal times for samples

OPTIMASI WAKTU MASERASI PARASETAMOL DALAM JAMU PEGAL LINU YANG BEREDAR DI BOGOR BARAT Bina Lohita Sari; Harry Noviardi; Nur Apriani Kartini
Jurnal Farmamedika (Pharmamedika Journal) Vol 2 No 1 (2017): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Jamu is a traditional medicine that is consumed by people.One type of herbal medicine on the market is Jamu Pegal Linu. Indonesian Govermment’s rule that this traditional medicine may not contain any synthetic chemical substance or drug functioned isolated compound. In reality there are still found some jamu pegal linu that contain medicine compound especially paracetamol. Analyzis chemical of drugs in herbal medicine has not been accompanied by the optimum times extraction. The aim of research to optimize of the time maceration and determine the contained of paracetamol in jamu pegal linu had circulated in Bogor Barat. Sample was taken by purposive sampling. Maceration from samples were using ethanol were within varying. Analysis of thin layer chromatography was using silica gel GF254 as the stationary phase, chloroform:ethanol (9:1) as the mobile phase with short waved UV as detection method. The results showed that 7 samples contained paracetamol from 10 samples of jamu pegal linu. The optimum of the time maceration between 0-30 minutes for herbal optimum simulation, sample D, F and S with a concentration of 2,49 to 22,33 %. The optimum of the time maceration between 60-90 minutes for the sample A, E and Q with levels of 4,47 to 7,12 %. Sample H had the optimum maceration time for 120 minutes with a concentration of 18.38%. Optimization of sample maceration time is dominated by the span of time between 30-90 minutes. Therefore, it is known that the samples of jamu pegal linu spread had maceration on the optimal time period between 30-90 minutes.

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Harry Noviardi

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Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Harry Noviardi

Contact Email harry.noviardi@gmail.com

Phone +622518323819

Journal Mail Official lppm@sttif.ac.id

Editorial Address Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

Location Kota bogor, Jawa barat INDONESIA

Abstract

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Contact Name
Harry Noviardi

Contact Email
harry.noviardi@gmail.com

Phone
+622518323819

Journal Mail Official
lppm@sttif.ac.id

Editorial Address
Jl. Kumbang No.23, Bogor, Jawa Barat, 16151

Location
Kota bogor,

Jawa barat

INDONESIA