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Majalah Biomorfologi (Biomorphology Journal)
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 53 Documents
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EFFECTS OF LOW DOSE EXPOSURE OF BORAX FOR 8 WEEKS ON GASTRIC ULCER FORMATION Audi Salman Faza; Linda Dewanti; Ema Qurnianingsih
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.038 KB) | DOI: 10.20473/mbiom.v30i1.2020.7-13

Abstract

Background: Borax, a carcinogenic toxicant, is illegally used as food additives frequently. Previous researches shown that high dose of borax exposure (300 mg/kg of BW) caused gastric ulcer, but low dose of borax, as found as usual dose in food, has not been frequently researched. Objective: The aim of this study was to analyze the effects of low dose of borax for 8 weeks on the formation of gastric ulcer. Materials and Methods: Twenty four young adult rats (Rattus norvegicus) were divided into 4 groups (Control, Group 1, 2, and 3). Borax doses of 50 mg/kg, 150 mg/kg, and 300 mg/kg were administered on groups 1, 2, and 3 respectively through sonde for 8 weeks; Control group was not exposed with borax. Body weight was monitored every 2 weeks. On the last day of the experiment, rats were euthanized and gastric ulcers were histopathologically analyzed using a microscope. The data were analyzed by the comparative test of Mann-Whitney and the significancy was set on p<0.050. Results: The results showed that body weight was significantly different on the 6th week between Control vs Group 1 (p=0.010) and Control vs Group 3 (p=0.043). The grade of gastric ulcer was found higher in Group 2 and Group 3 compared to Control (p=0.019 and 0.011 respectively). Conclusion: Both of low dose (150 mg/kg BW) and high dose (300mg/kg BW) of borax exposure for 8 weeks cause microscopic gastric ulcer on rats.
KARAKTERISTIK PASIEN TUBERKULOSIS TULANG BELAKANG DI RSUD DR. SOETOMO SURABAYA Amy Rosalie Sukamto; Primadenny Ariesa Airlangga; Tri Hartini Yuliawati
Majalah Biomorfologi Vol. 29 No. 1 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.077 KB) | DOI: 10.20473/mbiom.v29i1.2019.1-6

Abstract

Background: Spine tuberculosis or spondylitis TB is one of the most common found extrapulmonary form of Mycobacterium tuberculosis infection that can be rapidly transmitted. However, people’s alertness are still to be increased and this disease is still rarely investigated. Objective: To study the characteristics of spondylitis tuberculosis patients to enhance the understanding of the disease and improve alertness to its signs and symptoms. Material and method: This study was conducted by assessing patients’ medical records based on particularly the epidemiology, signs and symptoms, radiology and laboratory tests. Collected data were assessed retrospectively and analyzed descriptively. Results: Of 35 patients, most come from early adult age group which is ranged from 26 to 35 years old (25.72%), and 57.14% of the patients were female. Sorted from the most to least common found signs and symptoms are back pain (85.71%), formation of abscess (74.29%), formation of gibbus (54.29%), fever (37.14%), and significant weight loss (34.29%). In radiologic evaluation, spine destruction were found on 82.86% of the patients. Erythrocyte sedimentation rate (ESR) was evaluated from 30 patients, 90% of which had increased ESR to >30 mm/hour. The leukocyte count was based from 35 patients, which result was 71.43% of them had normal count. Conclusions: Spondylitis TB is mostly found in adult females with back pain as the most common symptom. Most patients had spine destruction. Largely had elevated ESR while their leukocyte count mostly remains within normal range.
CLINICAL PROFILE AND INCIDENCE OF INFECTION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS AT MEDICAL INPATIENT INSTALLATION, DEPARTMENT OF INTERNAL MEDICINE, DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2016 Desy Trilistyoati; Betty Agustina; Awalia Awalia
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.49-56

Abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unknown aetiology. SLE attacks multiple organs with diverse clinical manifestations. Most patients get immunosuppressant therapy that suppresses immune system, causing the body to be susceptible to infection. Objective: to describe clinical manifestations, laboratory abnormalities, and incidence of infections in SLE patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Materials and Methods: Cross-sectional descriptive observational study used medical records of 273 SLE patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Results: Clinical manifestations found in this study were malar rash 7.33%, discoid rash 2.93%, oral ulcer 8.42%, allopecia 16.48%, arthritis 26.74%, serositis 13.19%, kidney 35.9%, neurology 24.91%, anemia 73.71%, leucopenia 32.67%, lymphopenia 76.89%, and thrombocytopenia 33.86%. Laboratory abnormalities found in this study were hematology (anemia 73.71%, leucopenia 32.67%, lymphopenia 76.89%, thrombocytopenia 33.86%), kidney function (high serum creatinine levels 39.66%, high BUN levels 41.2%, hypoalbuminemia 62.6%), urine (proteinuria 68.21%, hematuria 51.79%) and liver function (high ALT levels 36.65%, high AST levels 29.86%). Infection occurred in 33.7% patients. The most common infections were pneumonia (70.65%), urinary tract infections (51.09%), and sepsis (35.87%). Conclusion: The most common clinical manifestations experienced by SLE patients are hematological disorder, kidney disorder, and arthritis. Prominent laboratory abnormalities are anemia, lymphopenia, and proteinuria. Infection is a common complication, with the most common types pneumonia, urinary tract infection, and sepsis.
THE SIMILAR CHANGES OF GLUCOSE LEVELS BEFORE AND AFTER MODERATE INTENSITY EXERCISE ACUTELY IN THE MORNING AND EVENING Ronik Harsono Kamal; Kristanti Wanito Wigati; Achmad Lefi
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.39-44

Abstract

Background: There is a lot of research on the importance of exercise but studies on the effective time of exercise regarding regulation of blood glucose levels are not clearly known. Objective: This study aimed to determine the comparison of changes in blood glucose levels before and after moderate intensity physical exercise in the morning and evening. Materials and Methods: Healthy men (n=34), age between 17-22 years, Body Mass Index (BMI) between 18.5-22.9 kg/m2 (normal Asia Pacific), participating in the morning (8.00 am) or evening group (20.00 pm) are asked to do moderate intensity physical exercise (55-70% of maximum heart rate) using ergocycle for a total of 40 minutes. Blood glucose levels 2 hours post prandial capillaries were taken before exercise and blood glucose levels after exercise were taken acutely. Results: The mean decrease in blood glucose levels in the morning group was ± 8.353 ± 9.16 mg/dL and in the evening group was ± 6.294 ± 10.10 mg/dL. Blood glucose levels decreased significantly for the morning group (p=0.002) and the evening group (p=0.021). The comparison of changes in blood glucose levels between the morning and evening groups was not significant (p=0.538). Conclusion: There was no difference between morning or evening exercise related to changes in blood glucose levels.
EVALUASI JARINGAN DALAM STUDI IN VIVO PEMBERIAN EKSTRAK PROPOLIS PADA MODEL LUKA INFEKSI Winona May Hendrata; Willy Sandhika; Agung Dwi Wahyu Widodo
Majalah Biomorfologi Vol. 29 No. 2 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (595.476 KB) | DOI: 10.20473/mbiom.v29i2.2019.32-39

Abstract

Background: Infection in wound could lead to various consequences including scarring and occurrence of sepsis. With increasing prevalence of resistant strain bacteria, option for treating infected wound need to be constantly expanded. Propolis, a product of honey bee, is a potential treatment which has been studied to have various effects including antibacterial, anti-inflammatory, and antioxidant. Objective: The study aims to assess the effect of propolis toward wound healing, by evaluating wound macroscopic and microscopic appearance. Material and method: Propolis extract were made using maceration technique using ethanol. Thirty Rattus norvegicus male rats were divided into six groups: three groups for treatment and three groups for control. Incision wound were made in the back and was infected with Methicillin ResistantStaphylococcus aureus (MRSA). Propolis was administered orally on daily basis. Wound excision for observation were done on day3, 5, and 7. The tissue were processed using haematoxylin-eosin (HE) staining for microscopic observation. The distance of normal tissue surrounding the wound were measured using image analysis program. Result: Macroscopic observation showed fewer visible wound in the propolis extract treated group. Measurement by microscopic observation on day 3 also demonstrated more narrow wound width in propolis extract treated group (405.75  110.11 μ) compared to the control group (806.20 644.41μ). Conclusion: The result of this study suggests that propolis extract by oral administration promotes the healing of infected wound as shown within microscopic and microscopic observation.
CORRELATION BETWEEN THE INITIAL-SURGERY AGE WITH THE HIRSCHSPRUNG’S DISEASE PATIENT STOOLING PATTERNS IN ULIN HOSPITAL BANJARMASIN, SOUTH KALIMANTAN, INDONESIA IN 2012-2015 Elvira Esmeralda Poerwosusanta; IGB Adria Hariastawa; Ariandi Setiawan; Sulistiawati Sulistiawati; Agung Ary Wibowo
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.66-69

Abstract

Background: Hirschsprung's disease may lead to gastrointestinal obstruction if not appropriately treated. The initial-surgery or colostomy is intended to decompress the large bowel, prevent enterocolitis, and the stooling-patterns can be measured after definitive surgery. Objective: To determine the correlation between initial-surgery age with stooling-patterns. Materials and Methods: We performed an analytic observational study in Ulin Hospital in Banjarmasin, South Kalimantan, Indonesia, from November to December 2015 with a total sample of 31 patients. The initial-surgery age was divided into before and after 30 days, while the stooling-patterns were divided into satisfied and not satisfied. Results: There was no significant correlation between initial-surgery age with stooling patterns. Most of the patients, 18/31 (58.1%), underwent initial-surgery after 30 days, and 23/31 (74.2%) had satisfied stooling patterns after surgery. Conclusion: No significant correlation between initial-surgery age and stooling patterns among Hirschsprung's disease patients.
THE PROFILE OF CORONARY HEART DISEASE PATIENTS IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA Ogiska Chaherfa Nadasya; Johanes Nugroho Eko Putranto; I Ketut Sudiana; Agus Subagjo
Majalah Biomorfologi Vol. 31 No. 1 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i1.2021.6-10

Abstract

Background: Coronary heart disease is a deadly disease for human. The incidence of coronary heart disease is different, so that this research reported the profile of coronary heart disease patients in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Objective: To analyze the profile of CHD patients in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from February to September 2018. Materials and Methods: A descriptive research based on the medical records. Results: There were 65 male patients and 20 female patients. There were 58% patients aged 50-60 years old, 24% patients aged more than 60 years old, and 18% patients are under 50 years old. The patients’ occupations were as follows: 42% civil servants, 36% private employees, 9% housewives, 5% retirees, 3% entrepreneurs, 1% for teacher, driver, fisherman, priest, and merchant. The complaints included chest pain (40%), shortness of breath (23.5%), PCI (4.6%), thump chest (1.2%), lower right abdominal pain (1.2%), right leg pain (1.2%), nausea (1.2%), vomitting (1.2%), cough (1.2%), dysentry (1.2%), and no complaint (23.5%). CHD patients in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia had the history of hypertension (30.6%), heart disease (22.6%), diabetes mellitus (21.9%), smoking (5.6%), COPD (0.8%), and no history of disease (12.9%). Sixty-one percent of the patients had blood sugar level of  ≥100 mg/dl, 19% patients had blood sugar level of <100 mg/dl, 20% patients did not have data. Conclusion: There were 85 patients, predominantly males of 50-60 years old. The most common occupation of the patients was civil servant and they came with major complaint of chest pain with the history of hypertension.
BODY MASS INDEX (BMI) OF CHILDREN WITH TETRALOGY OF FALLOT (TOF) Ovin Nada Saputri; Viskasari P. Kalanjati; Mahrus A. Rahman
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (529.179 KB) | DOI: 10.20473/mbiom.v30i1.2020.14-18

Abstract

Background: Malnutrition is a common cause of morbidity and mortality amongst children with TOF. Objective: To analyze the BMI profile of children with TOF aged 0 – 18 years at Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Materials and Methods: A cross-sectional study of the BMI from the medical record of TOF patients aged 0 – 18 years at the Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, since January 2016 to December 2017 was conducted. The data included gender, age group, demographic distribution, weight, and height. BMI was calculated by WHO formula reference; body weight (kg) divided by body height squared (m2), which was converted into z-score histogram. BMI classification was guided by the Government’s Anthropometry Standards for Nutritional Status Assessment. Result: From 84 TOF patients, there were 43 males (51%) and 41 females (49%). The most dominant age group was 0 – 4 years old (n=47;56%). The majority of patients were from outside of Surabaya (n=64;76.2%). Based on their BMI, 36 patients (42.9%) had severe underweight, 10 patients (11.9%) were underweight, and 35 patients (41.7%) were normal, whilst the rests (3.6%) were overweight. Conclusion: The number of male patients was slightly higher than female patients. The majority of TOF patients were 0 – 4 years old and resided out town of Surabaya. The predominant BMI found was the underweight and severe underweight below normal BMI.
VARIABILITAS TEKANAN DARAH INTRADIALISIS PASIEN PENYAKIT GINJAL KRONIS DENGAN HEMODIALISIS BERKELANJUTAN Maulana Muhtadin Suryansyah; Mochammad Thaha; Budiono Budiono
Majalah Biomorfologi Vol. 29 No. 1 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.275 KB) | DOI: 10.20473/mbiom.v29i1.2019.7-12

Abstract

Background: Various of studies report there was a link between changes in blood pressure during hemodialysis and the level of patient’s morbidity and mortality. Higher amount of mortality was found in groups of patients who have lower or higher blood pressure. Thus it is important to know the variability of blood pressure during hemodialysis. Objective: This study aims to determine blood pressure variability, namely systolic blood pressure and diastolic blood pressure during hemodialysis and determine the significance of changes in every hour of measurement. Material and method: The design of this study used a cross-sectional method with a total sample of 15 patients who have been diagnosed with Chronic Kidney Disease (CKD) and have been ungergone hemodialysis stably in the last 3 months. The data obtained were processed using paired T-Test and Wilcoxon test. Result: There was no significant difference in systolic blood pressure between hourly systolic blood pressure and a tendency to increase the mean systolic blood pressure during hemodialysis. In diastolic blood pressure, there was a difference between the mean diastole 3 and diastole 4, p = 0.007 (<0.05), while in other observation there were no significant differences. In the mean of diastolic blood pressure, there was a tendency to increase. Conclusion: During the hemodialysis process systolic blood pressure did not show a significant difference between the mean hours. In diastolic blood pressure, there was a significant difference between diastole 3 and diastole 4.
THE COMPARISON OF CIGARETTE CONSUMPTION TOWARDS SEMEN ANALYSIS IN ANDROLOGY POLYCLINIC OF DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2017 Yohanes Widyakusuma Eka Saputra; Kristanti Wanito Wigati; Rina Yudiwati; Ni Wajan Tirthaningsih
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.31-38

Abstract

Background: The habit of smoking tobacco is a lifestyle that has become a necessity for some people. Sometimes, social needs is the main reason for someone to have a smoking habit. Based on this problem, the level of cigarette consumption in the community has increased. Nowadays, the total number of couples visiting an infertility clinic is on the rise. This have led to an assumption among the community that smoking tobacco is one of the main factors causing male infertility. Objective: to compare light smokers and heavy smokers towards the results of semen analysis in infertile male patients. Materials and Methods: This study was an observational analytics, with a retrospective-cross sectional. The instrument used in this study was taken from medical records of the patients who visited the Andrology Clinic of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, for the period from January to December 2017. The observed semen analysis parameters were concentration, motility, and morphology for microscopic examination and liquefaction, pH, and volume for macroscopic examination, by following the inclusion and exclusion criteria. Results: Ninety-two samples of infertile male participants (50 light smokers and 42 heavy smokers) were included in this study. Semen analysis on its concentration, motility, spermatozoa morphology, as well as liquefaction, pH, and volume) towards the number of cigarette consumption showed no significant difference (p>0.05) between light smokers and moderate smokers. Conclusion: There was no significant difference between the light smoker and heavy smoker groups on the results of the semen analysis.

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