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Majalah Biomorfologi (Biomorphology Journal)
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 61 Documents
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PROFIL PENDERITA GASTRO ESOPHAGEAL REFLUX DISEASE (GERD) DAN NON-EROSIVE REFLUX DISEASE (NERD) DI RSUD DR. SOETOMO SURABAYA Irvinia Septarizka Putri Radjamin; Iswan Abbas Nusi; Viskasari Pintoko Kalanjati
Majalah Biomorfologi Vol. 29 No. 1 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.129 KB) | DOI: 10.20473/mbiom.v29i1.2019.13-18

Abstract

Background: Gastro Esophageal Reflux Disease (GERD) is a condition when food that had been ingested moves back up from the stomach to the esophagus periodically, causing heartburn. GERD cases that are followed up by esophagogastroduodenoscopy (EGD) can be diagnosed as Non-Erosive Reflux Disease (NERD) if there are no findings of mucosal damage at the esophagus. Objective: The objective is to study the overall prevalence of GERD and NERD patients on January until December of 2015, categorizing them according to age groups, gender, grade of esophageal mucosal damage according to Los Angeles grading, and also other EGD findings. Material and method: This is a descriptive research using secondary data collected from patients' medical record. Patients that are diagnosed as GERD or NERD are included as sample. Data are collected and processed by Microsoft Office Excel 2007. Result: A total of 122 medical records were collected, with 116 GERD patients and 6 NERD patients. There was increase of prevalence of GERD patients shown following the increase of age groups, while prevalence of NERD patients between age groups fluctuate. Both GERD and NERD patients are dominated by women, that is 62 patients (53.4%) and 5 patients (83.3%) respectively, compared to male, that is 54 GERD patients and 1 NERD patient. According to Los Angeles grading, the patients are mostly categorized as grade A (14.7%). However, there were 88 unclassified cases found so the result arguably needed a bigger sample and/ or data written in the medical record might not be clearly stated. The most dominant EGD finding in GERD patients was erosive gastritis (24.8%). Conclusion: There were 95% GERD patients and 5% NERD patients discovered in this study. The profile of GERD patients in this case was dominantly found in the age group of more than 50 years old, women, grade A, and with erosive gastritis in the EGD findings. The profile of NERD patients was not specific to a certain age group, but mostly found in women.
ASSOCIATION BETWEEN NUTRITIONAL STATUS AND THE OUTCOME OF PEDIATRIC PATIENT WITH DENGUE SHOCK SYNDROME Shidi Laras Pramudito; Dewi Ratna Sari; Ninik Asmaningsih Soemyarso
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.693 KB) | DOI: 10.20473/mbiom.v30i1.2020.1-6

Abstract

Background: The association between nutritional status and dengue infection is still considered controversial. Researches that study obesity and shock in pediatric patients with dengue hemorrhagic fever (DHF) has been widely carried out. However, researches that study the association between obesity and the outcome of patients with dengue shock syndrome (DSS) are still rarely done. Objective: The objective was to study the association of obesity in body mass index-for-age (BMI-for-age), gender, and age to the outcome of patients with dengue shock syndrome (recurrent shock or death). Materials and Methods: The research was analytical retrospective observational research with a case-control design using secondary data from the medical records of pediatric patients with DSS in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia during 2015. The analyses used to test the association of obesity (BMI-for-age), gender, age and the outcome of patients with dengue shock syndrome (recurrent shock or death) were the Chi-Square or Fisher Exact test. Results: The sample acquired was 60 data, consisting of 46 patients with DSS without recurrent shock or death and 14 pediatric patients with DSS experiencing recurrent shock or mortality. The frequency of boys and girls were found in equal numbers. Age group >5-10 years was found more common (45%). The results of the analyses test found no association between gender (p=0.542), age (p=0.314), and obesity (p=1.000) and the outcome of pediatric patients with dengue shock syndrome. Conclusion: There were no association found between obesity, age, and gender to the outcomes of pediatric patients with DSS at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
EFEK IBUPROFEN ORAL TERHADAP PERUBAHAN BERAT BADAN PADA MENCIT BETINA Anindya Marcha Angelina Djianto; Tri Hartini Yuliawati; Sri Ratna Dwiningsih; Widjiati Widjiati
Majalah Biomorfologi Vol. 29 No. 2 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.518 KB) | DOI: 10.20473/mbiom.v29i2.2019.27-31

Abstract

Background: Ibuprofen is one of the most used non-steroidal anti-inflammatory drugs (NSAID) due to its ease of access without the need of prescription. However, ibuprofen may cause side effects associated with gastrointestinal mucosal injury. The discomfort caused when eating may cause nausea and loss of appetite which leads to weight loss. Objective: This study was done to prove changes in body weight after treatment of oral ibuprofen using mice as test subjects. Material and method: This study used pre-test post-test control group design. 33 female BALB/c mice were grouped into 3 groups (P1, P2, P3). P1 is a control group which was given aquadest as placebo, P2 was given 52 mg/kg body weight of oral ibuprofen and P3 was given 104 mg/kg body weight of oral ibuprofen. Treatment lasted for 15 days. Results were analyzed using Kruskal-Wallis test and Mann-Whitney U test in IBM SPSS Statistics 22. Result: 80% of the mice had their body weights decreased with an average decrease of 0.91 g (±2.26) in group P1, average decrease of 2.2 g (±2.15) in P2, and average decreased of 4.11 g (±2.62) in P3. Statistical analysis showed that body weight changes of group P3 has significant difference (p = 0.009) compared to P1 and P2. Conclusion: It can be concluded that 104 mg/kg dose of oral ibuprofen caused a decrease in body weight of female mice.
THE PROFILE OF CHILDREN WITH CONGENITAL RUBELLA SYNDROME SUFFERING FROM HEARING DISORDERS IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA Raudhatuzzahra Kesuma; Haris Mayagung Ekorini; Tri Hartini Yuliawati
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.45-51

Abstract

Background: Congenital Rubella Syndrome (CRS) is an infection that can cause hearing loss which is commonly found in infants in Indonesia. The hearing screening of otoacoustic emission (OAE) and automated auditory brainstem response (AABR) is essential as an early screening to prevent speech and language development disorders which may reduce the social function of the patient in the future. Objective: To analyze the profile of children with CRS who suffer from hearing loss in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2015-2017. Materials and Methods: This research employed a descriptive retrospective study by collecting 118 secondary data from the medical records. Results: CRS was mostly found in 0-3 months age group (76 patients), and was dominated by males (62 patients). The most common signs and symptoms were congenital heart disease (49 patients), followed by hearing loss (37 patients). The serological results were mostly dominated by negative IgM and positive IgG (40 patients). The most dominant results of hearing screening test were OAE and AABR bilateral refer (45 patients). Conclusion: The profile of children with CRS suffering from hearing loss is various, depending on which country the research is conducted.
CHARACTERISTIC AND HISTOPATHOLOGICAL FEATURES OF PATIENTS WITH PERFORATED PEPTIC ULCER WHO UNDERWENT OPEN SURGERY THERAPY AT DR.SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA Alfi Nureta Rachmani; Mamiek Dwi Putro; Alphania Rahniayu
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.70-74

Abstract

Background: Perforated peptic ulcer is a form of complications from peptic ulcer and one of the most common emergency conditions in medicine. Objective: To describe the characteristic and histopathological features of patients with perforated peptic ulcer who underwent open surgery therapy in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Materials and Methods: This study was a descriptive study by observing patients’ data from medical records (secondary data) at Medical Record Center of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2016. Data obtained were analyzed descriptively. Results: Forty-six patients were identified (34 male, 12 female), most of them were between 56-65 years old for male and ≥66 years old for female. Majority of the subjects had a history of herbal medicine consumption (54%) as risk factors for developing perforated peptic ulcer and the most frequent comorbid diseases were diabetes and hypertension. The histopathological features found mostly were inflammation (100%), necrosis (44%), fibrosis (36%), granulation (17%) and  positive Helicobacter pylori (6%). Conclusion: Majority of the subjects were male, mostly between 56-65 years old for male and ≥66 years old for female. The histopathological features showed that all subjects had inflammations.
CORRELATION BETWEEN METABOLIC SYNDROME AND URIC ACID LEVEL IN THE OFFICE WORKERS OF A BUMN COMPANY IN SURABAYA Jihan Jauza Fairuz; Dewi Ratna Sari; Soebagijo Adi Soelistijo
Majalah Biomorfologi Vol. 31 No. 1 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i1.2021.11-17

Abstract

Background: Metabolic syndrome is a cluster of risk factor which consists of central obesity, hypertriglyceride, low High Density Lipoprotein (HDL) level, hypertension, and hyperglycemia. Its incidence among the office workers is increasing. Uric acid is often associated with cardiovascular disease while risk factor of cardiovascular disease is associated with metabolic syndrome. Objective: To analyze the correlation between metabolic syndrome and uric acid level in office workers. Materials and Methods: This study used medical record of health examination of PT Wijaya Karya Divisi IV male office workers aged of 20 – 60 years. The data taken consisted of abdominal circumference, blood pressure, triglyceride, HDL, fasting blood glucose, and uric acid levels. The diagnostic criterion of metabolic syndrome used in this study was National Cholesterol Education Program’s Adult Treatment Panel III (NCEP ATP III) that had been modified for Asians. The correlation of metabolic syndrome and serum uric acid level was analyzed by chi-square test with IBM SPSS Statistic 20 application. Results: There was no significant correlation (p=0.598) between metabolic syndrome and uric acid level in male office workers of PT Wijaya Karya Divisi IV. Conclusion: Metabolic syndrome and uric acid level among male office workers of PT Wijaya Karya Division IV had no correlation.
PREVALENCE OF DEPRESSION IN FIRST-YEAR MEDICAL STUDENTS AT UNIVERSITAS AIRLANGGA, SURABAYA, INDONESIA Dina Arini Izzah; Suksmi Yitnamurti; Nancy Margarita Rehatta
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.39-43

Abstract

Background: Depression is a mental disorder with a relatively high prevalence rate in medical students around the world. Medical students are often faced with a variety of pressures ranging from academic to social stress so that the prevalence of depression in medical students tends to be higher than general population. Objective: to find the prevalence of depression in medical students at Universitas Airlangga, Surabaya, Indonesia. Materials and Methods: This research was a descriptive cross-sectional study of first-year medical students at Universitas Airlangga, Surabaya, Indonesia in the academic year of 2017/2018. The data collection was carried out using Beck Depression Inventory II questionnaires as a measurement instrument and was analyzed by SPSS 16.0. Results: From 86 samples obtained from first-year students, 37.20% of them experienced mental conditions that were considered abnormal (mean score of 10.14 ± 7.093), starting from mild mood disturbance (23.26%) to the most severe category, severe depression (1.16%). There was no extreme depression category in this study. Furthermore, mean score of male subjects is 8.57 ± 6.120 while mean score of female subjects is 10.64 ± 7.351. Conclusion: This study revealed that the prevalence of depression in first-year medical students at Universitas Airlangga, Surabaya, Indonesia in the second semester of academic year 2017/2018 was quite high, which was more than one third of the total respondents, while the prevalence in female subjects was higher than in male subjects.
FACTORS RELATED TO THE INCIDENCE OF HIV/AIDS AMONG SHEMALE IN SURABAYA, INDONESIA Ridhwan Biosia Wiratama; Samsriyaningsih Handayani; Soetjipto Soetjipto
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.59-66

Abstract

Background: Acquired Immunodeficiency Syndrome (AIDS) is one of the diseases that cause death in the world caused by the Human Immunodeficiency Virus (HIV). Since it was first discovered in 1987 until December 2017, the number of person with AIDS was 102,667, and the number of person with HIV infections was 280,623. HIV/AIDS cases in East Java occupy the second highest position in Indonesia. Surabaya is the first city in East Java with 934 HIV cases in 2017. Shemale is one of the groups at risk of getting HIV/AIDS with prevalence was 24.82%. Objective: The purpose of this study was to analyze the factors that influence shemale related to the incidence of HIV/AIDS in Surabaya. Materials and Methods: This study was an analytic research using a cross sectional approach. The subject was 80 shemale respondents. Data were collected using questionnaires then analyzed using Chi-square test, with α=0.05. Results: The highest age group was 42-46 years (22.5%), the last level of education was dominated by high school (41.3%), and the most types of work were private employees (47.4%). There was no correlation between predisposing factors in the form of knowledge about HIV/AIDS and respondent's HIV status (p=0.729), there was no correlation between enabling factors in the form of condoms and respondent's HIV status (p=0.624), there was no correlation between the reinforcing factor in the form of family support with the HIV status of the respondent (p=0.674) and there was no correlation between preventive behavior and the HIV status of the respondent (p=0.540). Conclusion: The need for support between shemales for the dangers of HIV/AIDS and shemale should be more aware of their own health and environment with their social patterns.
IDENTIFICATION OF BACTERIAL CONTAMINANTS ON GLASSES USED BY STUDENTS OF FACULTY OF MEDICINE, UNIVERSITAS AIRLANGGA, SURABAYA, INDONESIA CLASS OF 2016 Hana Letitia Anjani; Marijam Purwanta; Maftuchah Rochmanti
Majalah Biomorfologi Vol. 31 No. 1 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i1.2021.18-23

Abstract

Background: People nowadays suffer from refractive disorder that declines the vision. The most common therapy to overcome this problem is to use glasses. The continuous use of glasses and the difficulties on disinfecting the entire surface can cause bacterial contamination. Those bacteria can cause various eye diseases. This fact pushed the researcher to find out if there were bacterial contaminants on glasses used by students of Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, class of 2016. Objective: To prove the species of bacterial contaminants and pathogenic bacteria on glasses used by students of Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia class of 2016. Materials and Methods: Cotton swab moistened in sterile distilled water was swabbed to 30 glasses on its inside lens and the part touching the nose. The sample was then inoculated on blood agar and Mac Conkey, and incubated for 24 hours in 37oC. Then, the isolates were identified macroscopically and microscopically. Results: The whole sample that had been examined was contaminated with pathogenic bacteria with risk of causing eye diseases. Those bacteria were identified as Bacillus sp. (50%), Pseudomonas sp. (46%), Staphylococcus aureus (20%), and Staphylococcus epidermidis (16%). Conclusion: The result of this research showed that there was contamination by bacteria on glasses used by students of Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia class of 2016. All bacteria found were pathogenic to the eye. This showed that glasses could become a reservoir of the pathogenic bacteria that could potentially cause recurring eye infection.
MATERNAL OBESITY INCREASES RISK OF PREECLAMPSIA AND DIABETES MELLITUS Naura Ega Kahayani; Hermanto Tri Joewono; Rio Wironegoro
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.44-48

Abstract

Background: Obesity in pregnant women has been linked to negative outcomes for both the mother and the fetus. Gestational diabetes, preeclampsia, and postpartum haemorrhage are all threats for mothers during pregnancy. These may also affect labor outcomes because fat accumulation in the pelvis makes obese pregnant women more likely to have a caesarean section. Objective: To analyze the outcome of maternal obesity in pregnancy in 2017. Materials and Methods: This was an analytic cross-sectional, observational study in pregnant women with obesity in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, within the period of January 1st – December 31st 2017 using medical records. Sample size was determined using cross-sectional sample size calculation with the result of n=162. After receiving approval of ethical clearance, medical records were collected and analyzed. The statistical analysis was done using chi-square test. Results: From a total of 162 subjects, most of the patients were 21-34 y/o (56.8%), under graduate (90.7%) and 58% of the subjects worked. Proportion of grade I, II and III were 60.5%, 22.2%, and 17.3%, and 67% suffered from complications such as PE, DM, PE with DM with percentages as follows: 56.2%, 4.9%, and 6.2%. Neonatal complications were preterm 42.6%, macrosomia 4.3%, stillbirth 4.9%, and low Apgar score 48.1%. No association was identified between maternal age and complications in grade I (p=0.764) and grade III (p=0.716). Obesity grades I and III had correlation with complications (p=0.035). Conclusion: No significant association was found between age and complications in grade III obesity, while there was significant correlation between obesity levels (grade I and grade III) and complications.

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