cover
Contact Name
Widodo
Contact Email
nst.journal.editor@gmail.com
Phone
+6282132116373
Journal Mail Official
nst.journal.editor@gmail.com
Editorial Address
Jalan Akasia Permai A.10, Malang, Jawa Timur, Indonesia
Location
Kab. malang,
Jawa timur
INDONESIA
Nusantara Science and Technology Proceedings
Published by Future Science
ISSN : -     EISSN : 26229692     DOI : -
NST Proceeding supports regional research communities to globalise their findings in Science and Technology by providing an open access, online platform in line with international publishing standards and indexing scholarly conference proceedings. The current emphasis of the NST Proceeding includes (but is not limited to) the following areas: Life Science, Mathematics, Eductation, Social Science, Medicinal Science and etc. All conference papers published on the NST Proceeding are fully Open Access. Open Access publications are freely and permanently available online to any reader, anywhere in the world without subscription to the publications in which these articles are published. Unrestricted use, distribution, and reproduction in any medium are permitted, provided the author/editor is properly attributed. NST Proceeding will provide high-quality peer review by scientific comittee and proofreading service by native speaker to make sure the language quality. We are the best in rapid publication processes for the open access content, maximum visibility and all-time availability for the published articles, citation tracking and indexing in a variety of databases.
Articles 7 Documents
Search results for , issue "Bioinformatics and Biodiversity Conferences (BBC)" : 7 Documents clear
Identification of Phenols and Triterpenoids Compounds in Michelia champaca for Treating Covid 19 Symptom by in Silico Khoirin Maghfiroh; Sri Widyarti; Sutiman B. Sumitro
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0706

Abstract

Michelia champaca is used by the community to treat mild diseases in the population. The plant Michelia champaca produces anti-inflammatory compounds. Some anti-inflammatory classes of compounds include Phenols and Triterpenoids. In disease prevention and treatment mechanics, COVID 19 in particular, the ability of anti-inflammatory compounds is very significant. Coronaviruses are viruses that were first described in 2019 attack the human respiratory system. Cough, a runny nose, and shortness of breath for fever are typical signs of viral infection. In defense mechanisms from coronaviruses, ACE2 is one of the inflammatory mediators used by the body. This study aimed to determine the potential of each group of Phenols and Triterpenoids compounds in Michelia champaca in binding ACE2 in Silico. The method used is docking molecule to find out the potential of anti-inflammatory compound groups. The ligands used in the study were Taraxerol, Taraxeron, Ferulic Acid, and Galic Acid. The protein used in the study was ACE2. The results showed that docking molecules for the Phenols and Triterpenoids groups separately showed that native ligand ACE2 could not bind to ligand copies of the Phenols and Triterpenoids groups. However, there are similar amino acid residues in ligand copy of Gallic acid with NAG. Gallic acid is a compound of phenols. The conclusion of this analysis is the complete ability of treatments and disease prevention in the Michelia Champaca plant as a result of COVID 19. However, the mechanism of interaction of plant compounds with proteins that play a part in the COVID 19 mechanism must still be demonstrated in vitro and in vivo in this research.  
Diabetic Retinopathy Detection Using GoogleNet Architecture of Convolutional Neural Network Through Fundus Images Amnia Salma; Alhadi Bustamam; Devvi Sarwinda
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0701

Abstract

The number of people who have Diabetes is about 422 million in the world. Diabetes is a group of metabolic disease characterized by elevated lev- els of blood glucose. The serious damage of blood vessels caused by Diabetes in the tissue at the retina is called Diabetic Retinopathy. Diabetic Retinopathy can cause severe blindness. Early detection can help patients find a suitable treatment and prevent the blindness. Opthalmologists can detect this disease by screening, but this method takes a long time, is very costly and need pro- fessional skills to perform it. In the big data era, many researchers use deep learning models for medical help. One of the models use image classification. We have designed a tool using image classification to help ophthalmologists detect diabetic retinopathy. In this research, we use image classification to classify Diabetic Retinopathy into two classes which are normal (No DR) and Diabetic Retinopathy. We use 200 datasets of fundus images that we obtain from Kaggle Database. We used deep learning model in this research that is one of Convolutional Neural Network architecture called GoogleNet. For training the model we used Python as programming languange with Pytorch library. GoogleNet has a very good performance for image classification and has an accuracy of 88%.
Use of SeedCounter Mobile App for Wild Species Seed Number Determination: A Preliminary Study Farid Kuswantoro
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0702

Abstract

Although its simple nature, seed counting is a crucial but demanding process in seed research and conservation. Manual seed counting, which usually takes a lot of effort and time, needs to be supplemented by new, easy-to-use, and accurate tools to simplify the process. Fortunately, the advance of information technology in recent years is significantly easing daily human life, including seed conservation and research. SeedCounter (https://cutt.ly/xhZFMZk) is a smartphone app which could help seed scientist to perform their seed counting process. However, as wild plant seeds come in various sizes, forms, and shapes, the app's ability to perform seed count of wild plant seeds need to be understood entirely. Thus, this study aims to understand the SeedCounter app's ability to perform seed counting in 20 wild plant seeds collected in Bali Botanic Garden Seed Bank Laboratory. We hope that the study will provide preliminary data for the app's potential to help seed conservation and research future efforts. SeedCounter app is downloaded and installed in a Nokia 6.1 Plus smartphone. Seeds photographed using the app with three replications conducted for each of the species. Seed counting is defined as a success if the app can count the seed number three consecutive times correctly. Data analysis was conducted descriptively. The study result showed that the SeedCounter app could correctly count seeds of ten plant species, which compares with 50% of the tested species. The result highlights SeedCounter's potential to simplified the counting process of some wild plant species seed.
Biodiversity of Gastropods in Intertidal Zone of Krakal Beach, Gunungkidul, Yogyakarta G. A. B. Y. P. Cahyadi; Ragil Pinasti; Assyafiya Salwa; Maghfira Aulia Devi; Lutfiyah Rizqi Fajriana; Nila Qudsiyati; Pinkan Calista; Rury Eprilurahman
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0703

Abstract

Krakal Beach is located in Gunungkidul Regency, Yogyakarta Special Region. This beach is built by coral reefs. The coral reef is an ecosystem that can support various biota to live on it by being a habitat for many species, such as Molluscs. Mollusc is the phylum that has the most members after Arthropods. Approximately 60,000 living species and 15,000 fossil species belong to Mollusc. The phylum Mollusc is divided into seven classes, one of which is Gastropods. Gastropods are Molluscs that move with their abdominal muscles. Molluscs are so diverse, so this research is aimed to study the biodiversity of Molluscs in the intertidal zone of Krakal beach, Gunungkidul, Yogyakarta. The research was conducted on October 4th, 2019 at 03.10 WIB. The research held when ecological parameters were ±21.3oC for water temperature, ±3.6% for salinity, and 7.5 for pH. The samples were collected using a purposive sampling method, preserved by using a dry preservation method, and identified by determining the morphological characteristics of the shell and referred to many references. This study found 7 families from the class Gastropod in the intertidal zone of Krakal beach, those are Aplustridae, Conidae, Cypraeidae, Mitridae, Muricidae, Nacellidae, and Turbinidae.
The Synergy Between Several Bacteria Isolated from the Biodiversity of UB Forest Coffee Litter in Vitro Gallyndra Fatkhu Dinata; Luqman Qurata Aini; Abdul Latief Abadi
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0704

Abstract

Exploration of bacteria from coffee litter in UB Forest has several new studies, which have the ability as a biocontrol agent. From previous research, it was known the potential of coffee litter bacteria as the single biological control against basal rot in shallots. This study aims to evaluate the ability of bacteria to synergize with other beneficial bacteria of coffee litter. The research consisted of the preparation of coffee litter bacteria isolates and synergy tests using the cross streak method. Based on the research results, not all bacteria can form a consortium. Bacteria that can synergize with each other are Pseudomonas sp., and Alcaligenes faecalis. Three bacteria that cannot be synergized with each other, are Bacillus mycoides, Clostridium sp. and Erwinia sp which produces clear zones up to more than 30 mm. This is preliminary research before starting a bacterial consortium. With this research, it is expected to be a solution for biological control from a consortium of beneficial bacteria from exploration in UB Forest.
In Silico Study of Secondary Metabolite in Vanilla planifolia to inhibit NUDT5 as Breast Cancer Target Alim El-Hakim; Anggiresti Kinasih; Rachmi Putri; Saifa Usni Putri; Febri Yuda Kurniawan; Endang Semiarti
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0705

Abstract

Breast cancer is a non-communicable disease that is the main killer for most women in the world. One of ten women with breast cancer will not survive more than five years after diagnosis. Breast cancer cases in Indonesia have been increased annually. As a nucleotide-metabolizing enzyme, NUDT5 (NUDIX hydrolase) catalyzes ADP to ATP nuclear that is used for cell proliferation. NUDT5 is a regulator of tumor driver in breast cancer proliferation. ATP nuclear synthesis can be blocked by inhibiting the NUDT5. The study of potential therapeutic inhibitors for NUDT5 was increased because the current treatment for breast cancer has side effects. Vanilla planifolia is a commercial plant from Orchidaceae which contains secondary metabolites and medicinal potential. This research aims to examine the metabolite of V. planifolia as the inhibitor of NUDT5 activity using molecular docking studies. V. planifolia metabolite and NUDT5 (5nwh) 3D structure were downloaded from the database (RSCB, Pubchem, and Dr. Duke), then the prediction of ADME (absorption, distribution, metabolism, and excretion) and potential bioactivity of the metabolite was analyzed by online structure-based prediction (SwissADME and Way2drug). After that, molecular docking was performed by AutoDock Vina. Three metabolites with the highest binding affinity scores were analyzed by visualization software (Discovery Studio). The result shows that Naphthalene, Caproic acid, Trimethylacetophenone, and Methyleicosane have the highest binding affinity. This result indicated that Naphthalene, Caproic acid, Trimethylacetophenone have the potential effect to inhibit NUDT5 enzyme thus decrease the potential of breast cancer.
Detection of Micronucleus, Nucleoplasmic Bridges, and Nuclear Buds Frequency in Peripheral Blood Lymphocytes of Cancer Patient Post-Radiation Fractionated Teja Kisnanto; Yanti Lusiyanti; Dyah Erawati; Suryadi
Nusantara Science and Technology Proceedings Bioinformatics and Biodiversity Conferences (BBC)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.0707

Abstract

Simple measurement of cytogenetic damage would be of great value for studying genetic risk factors, especially in radiotherapy for cancer patients. One cytogenetic technique that is easy and simple to quantify the damage caused by radiation exposure in cultured human lymphocytes is the micronucleus (MN). This research was conducted to study the induction of micronucleus (MN), Nucleoplasmic Bridge (NPB), and Nuclear Buds (NBUDs) in cancer patients after administration of fractionated radiation exposure total of 20 Gy. Peripheral blood lymphocyte samples obtained from eleven cancer patients as the study group and eleven from the healthy people as the control group were assessed. Both samples were then cultured and added cytochalasin-B to arrest cells during the cytokinesis stage. Its characteristics were observed in binucleated cells (BNC) with cytochalasin blocked micronuclei (CBMN) assay procedure. The number of MN, NPB, and NBUDs was evaluated per 1000 BNC for both the study group and control. The results showed that there was a statistically signif- icant difference (P <0.05) between the frequency of MN in the study group (82.18±39.93) compared to controls (13.18±4.94). Besides, the number of NPB and NBUD in the study group is relatively low. In conclusion, the iden- tification of MN formation in peripheral blood lymphocytes of post-radiation cancer patients has other molecular mechanisms such as NPB and NBUD. Also, demographic factors such as age can influence the appearance of MN, NPB, and NBUDs.

Page 1 of 1 | Total Record : 7


Filter by Year

0000


Filter By Issues
All Issue The 3rd International Conference on Vocational Innovation and Applied Sciences (ICVIAS) 2021 Seminar Nasional Agroteknologi Fakultas Pertanian UPN “Veteran” Jawa Timur 2021 Join Proceeding "Basic and Applied Science Conference (BASC) 2021 & 1st Education Research and Appli International Seminar of Research Month 2021 International Conference of Social Research with Multidisiplinary Approach (ICSRMA) 2021 4th Economics, Business, and Government Challenges 2021 5th International Seminar of Research Month 2020 3rd Economics, Business, and Government Challenges 2020 1st ICEMAC 2020: International Conference on Economics, Management, and Accounting Seminar Nasional Magister Agroteknologi Fakultas Pertanian UPN “Veteran” Jawa Timur Sains dan Teknologi Pertanian Modern Multi-Conference Proceeding Series B Multi-Conference Proceeding Series A Internationale Konferenz des Indonesischen Germanistenverbandes (iKoniG) International Seminar of Research Month Science and Technology in Publication, Implementation and Co International Seminar of Research Month Science and Technology for People Empowerment. International Conference on Life Sciences and Biotechnology (ICOLIB) International Conference on Global Resource Conservation (ICGRC) Federation of Islamic Medical Associations Bioinformatics and Biodiversity Conferences (BBC) 4th International Seminar of Research Month 2nd International Conference Eco-Innovation in Science, Engineering, and Technology 2nd Bioinformatics and Biodiversity Conference 1st International Conference Eco-Innovation in Science, Engineering, and Technology More Issue