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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

jetromi
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Published by TALENTA PUBLISHER

ISSN : 26860872 EISSN : 26860856 DOI : 10.32734

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.

Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme

Articles 86 Documents

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Correlation Between Adiponectin Receptor with Indices of Glucose Homeostasis and Mediators Of Insulin Sensitivity in Type 2 Diabetic Rats Treated With Puguntano (Curanga felterrae Lour.) Leaf Extract Dharma Lindarto; Brama Ihsan; Santi Syafril; Awaluddin Saragih
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 4 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

ABSTRACT Objective: Adiponectin receptors (AdipoR) regulates metabolism and has anti-inflammatory and insulin-sensitizing effects. We aimed to determine the relationships between AdipoR with parameters of glucose homeostasis (FPG, insulin, and HOMA-IR), and insulin sensitivity (PPAR-γ and p38MAPK) in T2DM rats treated with puguntano (Curanga felterrae Lour.) leaf extract. Methods: T2DM was induced in Wistar rats aged 8–10 weeks and weighing 180–200 g by high-fat diet (HFD) feeding and low-dose streptozotocin (30mg/kg.bw) administration. The rats were then allocated randomly to a treatment group and a control group (n=24 each). The treatment group was orally administered puguntano leaf extract (200 mg/kg.bb) once daily for 10 days. Subsequently, FPG and plasma insulin were measured, and HOMA-IR was calculated. Results: There was significantly difference between treatment group and control group on AdipoR and parameter of glucose homeostasis (FPG, Insulin, HOMA-IR) and insulin sensitivity (PPAR-γ, p38MAPK (all, p<0.01). In both groups, there were no significantly correlations between of AdipoR with all parameter of glucose homeostasis and insulin sensitivity except PPAR-ϒ (p <0.003) across the entire cohort of rats. Conclusion: Our data suggest that puguntano could improve glucose homeostasis, insulin sensitivity and molecular mediators of insulin sensitivity. There were no significantly correlated between improvement of AdipoR with glucose homeostasis and molecular mediators of insulin sensitivity in T2DM.

The Relationship Between Body Mass Index and Inflammatory Parameters in HIV Patients Treated with Antiretrovirals Lydia Theresia; Dharma Lindarto; Santi Syafril; Tambar Kembaren
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Antiretroviral administration affects weight gain and inflammation in HIV patients. The purpose of the study was to assess the relationship of body mass index with inflamation parameters in HIV patients who ARV therapy. In 40 HIV patients (stage III-IV) treated with ARV (FDC 87%, Durival Efaviren 7.5%, Tenofovir, Huviral, Aluvia 2.5%, and Tenofovir, Huviral, Neviral 2.5%) conducted observational analytics with crosssectional design. CD4 examination was carried out flowcytometrically, BMI measured by formula weight (kg) divided by height squared (m2), waist circumference (WC) measured by ribbon between costae arcus and anterior superior iliac spine, albumin measurement with Brom Cresol Green (BCG) method. There is a significant correlation between BMI with WC and CD4 (r=0.61, p<0.001 and r=0.38, p<0.001, respectively). There is no correlation between BMI and duration of ARV treatment, albumin and leptin. ARV treatment in HIV patients will affect weight and inflammatory markers.

Postpartum Thyroiditis: A Case Report Jessica Patricia Pangaribuan; Santi Syafril
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

ABSTRACT: Background: Postpartum thyroiditis (PPT) is a thyroid dysfunctionn syndrome which is temporary or permanent that occurs 1 year after giving birth or abortion. The occurrence of postpartum thyroiditis is 5 – 10% of postpartum women in the world. It is caused by an inflammation of the thyroid gland which leads to a destruction of the thyroid follicle and proteolysis of thyroglobulin. Case presentation: A woman, 31 years old, was admitted to the hospital complaining an enlargement on her neck. The patient said her the enlargement keeps getting larger and she also complained a feeling of something stuck in the throat. The patient also complained a hoarse voice. The patient has just given birth of her second child 5 months ago. From a hematologic examination, radiologic, and blood culture, the patient was diagnosed with Postpartum Thyroiditis. The patient was given Euthyrox therapy and will undergo repeated evaluation after 1 months of the therapy. Conclusion: We reported a case of Postpartum Thyroiditis that was treated comprehensively, and showed a good prognosis.

Pituitary Macroadenoma Manifesting As Acromegaly: A Case Report Dian Primadia Putri; Brama Ihsan Sazli
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: Acromegaly is an uncommon clinical disorder driven by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Over 99% of patients with acromegaly harbor a GH emitting pituitary adenoma. Pituitary tumors represent about 15% of essential intracranial neoplasms. Case presentation: A 38 years old woman, was referred to the H. Adam Malik central public hospital on December 15th, 2020, with chief complaints of enlarged fingers and toes. The patient complained that the patient's fingers and toes were getting bigger in the past 2 years. The brain MRI was performed showed intrasella spherical intensity lesions measuring ± 2.3x1.5x2 cm with the impression of macroadenoma. The patient later diagnosed with acromegaly due to pituitary macroadenoma. Therefore the patient was treated with administration of sandostatin injection, novorapid 6-6-6 IU SC, then 0-0-12 IU SC, 3x1 salt capsules. The patient is also consulted to the neurosurgery department for surgical management plans and a consulted to the Ophthalmology Department. Conclusion: We report an instance of acromegaly suspected because of pituitary macroadenoma in a patient with unmistakable clinical highlights, with comprehensive management.

Differences in Inflammatory Parameters of Child-Pugh B and Child-Pugh C Scores of Liver Cirrhosis with Hepatorenal Syndrome Lider Olmen Panggabean; Gontar Alamsyah Siregar; Masrul Lubis
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: Child-Pugh score is used to predict the poor prognosis of liver cirrhosis patients. The study objectives analyzed differences in inflammatory parameters of Child-Pugh B and Child-Pugh C of liver cirrhosis with hepatorenal syndrome. Method: Desain's study is cross-sectional in liver cirrhosis patients with hepatorenal syndrome. This research was approved by the Health Research Ethics Commission FK USU / RSUP H. Adam Malik Medan and meets the criteria of inclusion or exclusion. Diagnosis of Liver cirrhosis Child-Pugh B and Child-Pugh C score is done by clinical examination, laboratory, and ultrasound, CT scan, MRI. The hepatorenal syndrome was diagnosed using Criteria International Ascites Club, 2007. Results: The sample number of this study was 26 liver cirrhosis with hepatorenal syndrome patients consisting of Child-Pugh B patients 9 patients and Child-Pugh C patients 17 patients. The comparison between Child-Pugh B and Child-Pugh C has significant differences in leukocyte, Na, Cl, SGOT, and CTP. There is a significant correlation between CTP and leukocytes, platelets, Cl, creatinine, GFR, albumin, total bilirubin, and glued bilirubin. Conclusion: There is no clear difference in the inflammatory parameters of the Child-Pug B and Child-Pug C scores in liver cirrhosis with hepatorenal syndrome.

Knowledge Level of Grade XII Senior High School Students Regarding HIV/AIDS Stanley Lesmana; Riyadh Ikhsan; Azriya Azka
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: AIDS (Acquired Immunodeficiency Syndrome) is a collection of symptoms or diseases caused by a decrease in the immune system from the body due to infection from the HIV (Human Immunodeficiency Virus) which belongs to the retroviridae family. Teenagers themselves are vulnerable to HIV/AIDS. The right and precise knowledge of HIV and AIDS is important in HIV prevention efforts in adolescents. Method: This research is a descriptive research with cross-sectional design. The sample population of this study was grade XII senior high school students of the 2020/2021 at Methodist – 2 Medan by sampling total sampling. This study was analyzed univariately to look at the descriptive images. Result: From the results of this study, it has obtained that the knowledge level of students grade XII Methodist - 2 Medan had good knowledge about HIV / AIDS with the number of 144 people (70.6%). Conclusion: From this study, it was found that the level of knowledge about HIV/AIDS was mostly in a good category.

The Level of Handwashing Knowledge and Behavior of Yos Sudarso High School Medan Students' During The COVID-19 Pandemic Cindy Elvira; Causa Trisna Mariedina
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: The COVID-19 (Coronavirus Disease 2019) outbreak which was first detected in Wuhan, China, in December 2019, has spread rapidly. One way of preventing and controlling infection in the community is by washing hands thoroughly and regularly. The purpose of this study was to determine the level of handwashing knowledge and behavior of Yos Sudarso High School Medan students’ during the COVID-19 pandemic. Method: The design used was one group pretest-posttest design. The type of data is primary data obtained through online questionnaires using a total sampling technique. Results: Of the 76 respondents, the level of knowledge on handwashing was dominated by the low category, namely 65 people (85.5%) and the good category of handwashing behavior, namely 59 people (77.6%). After being given information, the level of the good knowledge was 35 people (46.1%) and the good behavior was 66 people (86.8%). Students have a low knowledge about handwashing but have a good handwashing intensity behavior during the COVID-19 pandemic. Conclusion: Given information, there is an increase on the level of handwashing knowledge and behavior of Yos Sudarso High School Medan students’ during the COVID-19 pandemic.

Relationship Between BMI Degree and Non-Alcoholic Fatty Liver Disease Risk Factors Chairunnisa Fitri Marpaung; Gontar Alamsyah Siregar; Ilhamd
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 1 (2021): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: Obesity is a major risk factor for cardiovascular disease, type 2 diabetes, high blood pressure, sleep apnea, psychological issues, some musculoskeletal conditions, and some cancers. The aim of the study to evaluate the correlation between BMI and risk factor of non-alcoholic fatty liver disease (NAFLD). Method: The research was conducted cross-sectionally in NAFLD patients who were treated at RSUP H Adam Malik Medan and got approval from the Ethics Commission for Health Research. Sample research is NAFLD patients who are taken in consecutive sampling that meets the criteria of inclusion and exclusion. Body mass index (BMI) is obtained by dividing a person's weight in kilograms by their height in square meters, define obesity (OB) if BMI > 25, overweight (OW) BMI 23-24.9, and normoweight (NW) BMI 18.5-22.9. Diagnose NAFLD by performing ultrasound examination, resistin and adiponectin examination with ELISA (Sandwich Immunoassay), liver function according to IFCC (International Federation of Clinical Chemistry), and albumin checked by BCG method. Result: There were 67 patients (NM=32, OW=15, OB=20) NAFLD with an average age of 42.1± 11.9 years, Comparison of NAFLD risk factors in normoweight, overweight, and obesity, showing very significant results (all p<0.001). There is a very significant correlation between BMI and all NAFLD risk factors (all p<0.001). Conclusion: There are very significant correlates between BMI and all inflammatory factors of NAFLD.

Knowledge Level about Mother to Child Transmission of HIV/AIDS among Medical Student in Universitas Sumatera Utara Albert Fiorentino Cuwardy; Deri Edianto
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

ABSTRACTBackground: HIV/AIDS is one of the diseases that has been a global problem for a long time. In 2018, there were 37.9 million people worldwide infected with HIV and 1.7 million were children. Knowledge of the prevention of HIV transmission from mother-to-baby is very important as one of the prevention options. The aim of research knowing the level of knowledge of students of the Faculty of Medicine, Universitas Sumatra Utara in 2017 against HIV transmission from mother to child.Method: Research method conducted using online survey method with cross sectional design. The samples used are all students based on total sampling. The study used univariate analysis to see descriptive images with primary data sourced from online questionnaires. Result: The level of knowledge of students of the Faculty of Medicine, University of North Sumatra in 2017 in the category of both 128 people (63.7%), enough 67 people (33.3 %), and less 6 people (3%).Conclusion: Students of the Faculty of Medicine, University of North Sumatra in 2017 have good knowledge about HIV transmission from mother to child.

Self-Perception of Co-Assistant Students Regarding The Covid-19 Pandemic Chairiza Muttaqien; Putri Chairani Eyanoer; Ririe Fachrina Malisie; Hemma Yulfi
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background: At the beginning of 2020, the world was shocked by a new type of coronavirus (SARS-CoV-2) whose disease was called Coronavirus disease 2019 (COVID-19). The research aims to determine the self-perception of Co-Assistant students regarding the COVID-19 pandemic. Method: The study was designed cross-sectional, which was conducted via sharing online links. Respondents must Co-Assistant students from a medical faculty in Indonesia and participated in the questionnaire filling between June 2020 and October 2020. This research is a descriptive study with a cross-sectional approach and conducted using primary data (online questionnaire Results: One hundred forty-nine students (149) of Co-Assistant students from several medical faculties all over Indonesia met the inclusive criteria. The samples were dominated by female respondents at 103 students (69.1%), while the male respondent accounted for only 46 students (30.9%). The first year of the Co-Assistant program with 94 respondents (63.1%) followed by the second year of the Co-Assistant program with 55 respondents (36.9%). The highest mean score in the fear zone came from the "first year of Co-Assistant program" group and the highest mean score in the learning and growth zone came from the "second year of Co-Assistant program" group. Conclusion: The highest mean score in the fear zone came from the "first year of Co-Assistant program" group and the highest mean score in the learning and growth zone came from the "second year of Co-Assistant program" group.

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Contact Name Dharma Lindarto

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Editorial Address Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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Contact Name
Dharma Lindarto

Contact Email
jetromi@usu.ac.id

Phone
+6282168842564

Journal Mail Official
jetromi@usu.ac.id

Editorial Address
Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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Unknown,

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INDONESIA