cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota surakarta,
Jawa tengah
INDONESIA
Biomedika
Published by Universitas Muhammadiyah Surakarta
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Arjuna Subject : -
Articles 399 Documents
 2   3   4   5   6 
PERAN BASOFIL DALAM IMUNITAS TERHADAP CACING Jatmiko, Safari Wahyu
Biomedika Vol 4, No 1 (2012): Biomedika Februari 2012
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Basophils are polymorphonuclear leukocytes that play an important role in immunity. Basophils can be activated by antibodies and other molecules. Basophils are able to recognize antigens of worms and give some responses. Basophils involvement in immunity againt worms are played by migratingto the worm infected tissue, trigger eosinophilia and eosinophil migration into the tissue, activating mast cells, triggering the formation of AAM, directing Th cell polarization toward Th2 cells, and triggers immunoglobulin class switching to produce IgE.Keywords:Basophil, Helminthiasis
Angka Kejadian Komplikasi Lambat Pascaoperasi Prostatektomi Transvesikal dan Reseksi Transuretral pada Pasien Pembesaran Prostat Jinak Hasbullah, Bakri
Biomedika Vol 1, No 1 (2009): Biomedika Februari 2009
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Transurethral Resection Prostatectomy (TURP) and Transvesical Prostatectomy (TVP) are the two methods of operation for BPH. The aims of this study are to find out the late complication after prostatectomy between TVP dan TURP. Data were collected from January 1 st 2004 to December 31 st 2004 with prospective cohort study. There were 67 of 90 post prostatectomy BPH patients who met the inclusion criteria. Data were listed into age and comorbid factors are hypertension (HT), ischaemic heart disease (IHD), chronic obstructive pulmonary disease (COPD), Diabetes Mellitus (DM). Post prostatectomy late complications are erectile dysfunction (ED), retrograde ejaculation (RE), urethral stricture (US), urinary incontinence (UI). Data were analyzed statistically with the t-test. There were 67 patients (median age 65,81 years range 51-86 years) inclusion in this study 12 patients has performed TVP (17,9%), 55 patient was performed TURP (82,1%). Comorbid factors were HT (19,4%), IHD (16,4%), COPD (11,9%), DM (4,5%). The most frequent age of TVP were 7 th decade (50%), TURP were 6 th decade (41,82%).The late complication after TVP and TURP for BPH were not significant different (p>0,05). The most frequent late complications after prostatectomy of the TVP and TURP is ED. Study about the late complications after operation of the BPH between TVP and TURP, statistically were not significantly different.Keywords: BPH, open prostatectomy, TURP, late complication.
KORELASI KANDUNGAN FENOLIK DAN AKTIVITAS ANTIOKSIDAN DAUN JAMBU METE Kusumowati, Ika Trisharyanti Dian; Melannisa, Rosita; Ratri, Kartikaning
Biomedika Vol 3, No 2 (2011): Biomedika Agustus 2011
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The ethanolic extract of Anacardium occidentale L. leaves contains phenolic compounds,  avonoids, alkaloids, saponins, tannins, and steroids that could have antioxidant activity. The aim of this research was to determine the correlation between the antioxidant activity and the phenolic compounds of the ethanol extract of Anacardium occidentale L. leaf. The DPPH methode was used to determine the antioxidant activity. The total phenolic determined using Folin-Ciocalteu reagent. There was a positive correlation between antioxidant activity and total phenolic content in the ethanolic extract of cashew leaf with correlation coef cient R2 = 0.5888.Keywords: Anacardium occidentale L., antioxidant, phenolic compounds
FARMAKOGENETIK PENGOBATAN BETA 2 AGONIST DAN STEROID PADA PENDERITA ASMA Sutrisna, EM
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the worldwide about 300 million people have asthma. β-2 agonists and steroids are widely prescribed drugs in the treatment of asthma. Different responses raises the suspicion of a genetic infiuence on the host’s response to the treatment of this disease. The purpose of this review is to provide a comprehensive understanding of the infiuence of genetic factors on the treatment of asthma. This review is done by the method in Pubmed search using keywords Pharmacogenetic asthma; polymorphism beta agonist AND asthma. The analysis shows that there are several genes that affect treatment response. ADRB2 gene affects the bronchodilatation response for asthmatics treated with β-2 agonist. CRHR1 gene polymorphism, Glucocorticoid-complex genes, and CER2 genes and TBX21 genes affect the response to corticosteroids inhalers.Keywords: Asthma, Pharmacogenetics, Treatment response
HUBUNGAN TINGKAT PENGETAHUAN TENTANG PENYAKIT DM DENGAN PENGENDALIAN KADAR GLUKOSA DARAH PADA PASIEN DM TIPE II DI RSU PKU MUHAMMADIYAH SURAKARTA Perdana, Ananda Asriany; Ichsan, Burhannudin; Rosyidah, Devi Usdiana
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The level of DM knowladge with blood glucose controll was instrument to help diabetic patients did the management of diabetes. Diabetic patients who had more and better informations about DM, than they changed their life style, that could controll their disease. So, they would have longer and better live. This research was observational analytic research with cross sectional approach. The sample was 33 diabetic patients who cared their disease in RSU PKU Muhammadiyah Surakarta and who had ful lled the predeterminated criteria, it was taking with the purposive sampling technique. The research instrument used the level of DM knowladge quesioner and medical record. From the statistical calculation, it was obtained that P value = 0,042. It could be concluded that there was signi cant the relationship between the level of DM knowladge with blood glucose controll of type 2 diabetic patients. Pasients who had high level knowladge would have good blood glucose controll.Key Words : Level Knowladge, Diabetes Melitus of Type 2, Blood Glucose
PERBANDINGAN PEMBERIAN BUFFERED PEHAKAIN DENGAN FRESHLY MIXED LIDOKAIN- EPINEFRIN PADA PERSEPSI NYERI KARENA INFILTRASI ANESTESI LOKAL Pramuningtyas, Ratih
Biomedika Vol 4, No 2 (2012): Biomedika Agustus 2012
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Over the last decade, there has been a rise in the number of surgical procedures being perfomed under local anethesia. The infiltration of the local anesthetic is the most painful part of this procedures, and pain associations can develop into avoidance behaviors in future procedures. Several techniques were used to reduce the pain of local anesthetic infiltration. The objective of this study is comparing the effect of Buffered Pehacaine versus freshly mixed lidocaine-epinephrin in reducing the pain of local anesthetic infiltration. Six subject were recruited for this study. Each subject was received 2 kind of treatment. Subject rated pain using Visual Analog Score. Pain score were compared using paired t test. Sixty seven percent (67%) subjects reported that pain of infiltration was lower in Buffered pehacaine than freshly mixed lidocaine-epinephrine. The difference was not statistically significant. There are no significant difference between Buffered Pehacaine versus freshly mixed lidocaine-epinephrin in reducing the pain of local anesthetic infiltrationKeywords : local anesthetic infiltration, lidocaine, pehacaine
UJI EFEK PEMBERIAN EKSTRAK ETANOL 70% BIJI BUAH TERUNG UNGU (SOLANUM MELONGENA L.) TERHADAP KADAR KOLESTEROL HDL SERUM DARAH TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) GALUR WISTAR Fajriyatun, Baiq Nova; Sutrisna, EM; Nirlawati, Dona Dewi
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Extract of eggplant fruit (Solanum melongena L.) seed is a plant that has anti-hypercholesterolemia effect on the state of dyslipidemia. One of the compounds contained in them are fl avonoids nasunin which can increase levels of HDL cholesterol (high density lipoprotein). HDL cholesterol is considered as a compound have the ability to remove excess cholesterol from the arteries, and therefore called good cholesterol. This study is a laboratory experimental research using pretest and posttest control group. The sample consisted of 25 rats were divided into 5 groups. Group I is a negative control (-), Group II is a positive control (+), group III was treated 1 (dose 1), group IV was treated 2 (dose 2), and V is the treatment group 3 (dose 3). Each group was given a high-cholesterol diet. Negative and positive control group were not given the extract of fruit seed of eggplant, the treatment groups III, IV, and V were given the extract of fruit seed of eggplant with each dose of 20 mg/kg, 40 mg/kg, 80 mg/kg were given for 4 weeks. HDL cholesterol levels will be measured before and after cholesterol diet and calculated each week after giving of the extract. The data obtained tested with statistical tests One-Way Anova. HDL cholesterol positive control group and the treatment group showed signifi cant differences between groups. Treatment groups 1 and 2 levels of HDL cholesterol lower than the positive control group and the treatment group 3. Extract of eggplant fruit seed dose of 80 mg/kg show an increase in HDL cholesterol levels were signifi cantly (p <0.05). The 70% ethanol extract of eggplant fruit seed at a dose of 80 mg/kg can increase HDL cholesterol levels signifi cantly.Keywords : extract of eggplant fruit seed, hypercholesterol, HDL cholesterol
PENGARUH MEROKOK TERHADAP FAAL PARU Basuki, Sri Wahyu; Nilawati, Dona Dewi
Biomedika Vol 3, No 2 (2011): Biomedika Agustus 2011
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Indonesia is thethirdlargestcigaretteusersafter Chinaand India,which reached 146.86 million inhabitants. Smoking behavior is engulfi  ng all circles, including children. Dangers of smoking are undoubtedly makes a person not a long life. When compared with non smokers, smokers aged on average 10 years shorter and spend millions of dollars. Inhaled cigarette smoke may accelerate the decline in lung physiology caused by changes in the structure and function of the airway or parenchyma (tissue) in the lung. The objective of this study was to determine differences in pulmonary function (Vital Capacity/VC, Forced Vital Capacity/FVC, and Forced Vital Capacity of the fi  rst second/FEV1) in male smokers and non smokers at the Medical Faculty of uhammadiyah University of Surakarta and determine the effect of smoking on pulmonary function. This study used analytical research design with cross sectional approach. The subject of this study was the active student and employee at the Medicine Faculty, Muhammadiyah University of Surakarta. Purposive sampling method was random sampling. The results were tested by statistical tests of independent t-test with SPSS 16.0.The sample size obtained was 40  people consisted of 20 (50%) sample of smokers and 20 (50%) sample of non-smokers. There was not difference VC between male smokers and nonsmokers with p = 0.390. There was difference FVC between male smokers and nonsmokers with p = 0.000. There was difference FEV1 between male smokers and nonsmokers with p = 0.025.This study showed the difference in FVC and FEV1 between male smokers and nonsmokers in the Medicine Faculty, Muhammadiyah University of Surakarta, but VC did not.
HUBUNGAN SELF DIRECTED LEARNING READINESS DENGAN TINGKAT KECEMASAN MAHASISWA TINGKAT PERTAMA TAHUN 2010-2011 FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SURAKARTA Triastuti, N. Juni
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The anxiety level can be infl uence learning achievement. While the self directed learning readiness can be infl uence learning achievement. The purpose of this study was to determine wheter self directed learning readiness have relationship with the anxiety level at the fi rst medical education student of University Muhammadiyah Surakarta. This study involve 49 responden that receive kuisioner about self directed learning readiness and kuisioner of Hamilton Anxiety Scale. With Spearman test, , the result of this study show that Sig value of the psyche anxiety is 0.550, physics anxiety 0.260 and general anxiety 0.079. This value indicate that there are not signifi cant relationship between self directed learning readiness and the anxiety level. Based on study result, we concluded that self directed learning readiness didn’t have signifi cant relation with the anxiety level at the fi rst medical education student of University Muhammadiyah Surakarta.Keywords: self directed learning readiness, the anxiety level.
PENGARUH KEPADATAN HELICOBACTER SPP DAN DERAJAT INFLAMASI TERHADAP KERUSAKAN HISTOPATOLOGIK PADA GASTRITIS KRONIK: REEVALUASI ARSIP SLIDE GASTRITIS KRONIK DI LABORATORIUM PATOLOGI ANATOMI RSUP DR KARIADI TH 2011-2013 Kurniawati, Eny Dyah; Sadhana, Udadi; Wijaya, Indra
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Infeksi Helicobacter pylorii (Hp) telah menjadi masalah kesehatan yang mendunia, sebagai penyebab utama gastritis kronik, tukak lambung dan keganasan, akan tetapi mekanismenya dalam menimbulkan gastritis kronik masih belum sepenuhnya dimengerti. Penelitian ini bertujuan untuk mengetahui pengaruh kepadatan kuman Helicobacter spp dan derajad inflamasi terhadap derajat kerusakan histopatologik pada penderita gastritis kronik serta prevalensinya di RSUP dr.Kariadi. Penelitian ini adalah penelitianobservasional dengan pendekatan potong lintang dengan sampel sebanyak 70 slide arsip dari laboratorium Patologi Anatomi RSUP dr.Kariadi mulai 1 Januari 2011 – 31 Desember 2013 yang telah didiagnosis sebagai gastritis kronik disertai kuman Helicobacter spp positif oleh dokter spesialis Patologi Anatomi. Data kepadatan kuman Helicobacter spp, derajat inflamasi dan derajat kerusakan histopatologik gaster dianalisa dengan uji Kruskal Wallis, dilanjutkan dengan uji Mann-Whitney U dan uji korelasi Spearman. Prevalensi gastritis kronik dengan kuman Helicobacter spp positif di RSUP dr.Kariadi pada tahun 2011 sebesar 58%, tahun 2012 naik menjadi 70% dan tahun 2013 menjadi 79%. Terdapat perbedaan yang tidak bermakna antara derajat kepadatan kuman Helicobacter spp dengan derajat inflamasi baik aktif maupun kronik dengan korelasi positif yang lemah dan perbedaan yang bermakna pada atrofi kelenjar yang merupakan bagian dari derajat kerusakan histopatologik gaster dengan korelasi positif yang lemah pada penderita gastritis kronik. Terdapat perbedaan yang signifikan antara derajat inflamasi baik aktif maupun kronik dengan derajat perubahan histopatologik dengan korelasi positif pada penderita gastritis kronik. Derajad inflamasi yang terjadi pada gastritis kronik akibat kuman Helicobacter spp berpengaruh pada derajat kerusakan histologik pada penderita gastritis kronik.Kata kunci : Kepadatan kuman Helicobacter spp, derajat inflamasi, derajat kerusakan histopatollogik, gastritis kronik.

Page 4 of 40 | Total Record : 399

 2   3   4   5   6 

Filter by Year

2009 2022


Reset
Filter By Issues
All Issue Vol 14, No 2 (2022): Biomedika Agustus 2022 Vol 14, No 1 (2022): Biomedika Februari 2022 Vol 13, No 2 (2021): Biomedika Agustus 2021 Vol 13, No 1 (2021): Biomedika Februari 2021 Vol 12, No 2 (2020): Biomedika Agustus 2020 Vol 12, No 1 (2020): Biomedika Februari 2020 Vol 11, No 2 (2019): Biomedika Agustus 2019 Vol 11, No 1 (2019): Biomedika Februari 2019 Vol 11, No 1 (2019): Biomedika Februari 2019 Vol 10, No 2 (2018): Biomedika Agustus 2018 Vol 10, No 2 (2018): Biomedika Agustus 2018 Vol 10, No 1 (2018): Biomedika Februari 2018 Vol 10, No 1 (2018): Biomedika Februari 2018 Vol 9, No 2 (2017): Biomedika Agustus 2017 Vol 9, No 2 (2017): Biomedika Agustus 2017 Vol 9, No 1 (2017): Biomedika Februari 2017 Vol 9, No 1 (2017): Biomedika Februari 2017 Vol 8, No 2 (2016): Biomedika Agustus 2016 Vol 8, No 2 (2016): Biomedika Agustus 2016 Vol 8, No 1 (2016): Biomedika Februari 2016 Vol 8, No 1 (2016): Biomedika Februari 2016 Vol 7, No 2 (2015): Biomedika Agustus 2015 Vol 7, No 2 (2015): Biomedika Agustus 2015 Vol 7, No 1 (2015): Biomedika Februari 2015 Vol 7, No 1 (2015): Biomedika Februari 2015 Vol 6, No 2 (2014): Biomedika Agustus 2014 Vol 6, No 2 (2014): Biomedika Agustus 2014 Vol 6, No 1 (2014): Biomedika Februari 2014 Vol 6, No 1 (2014): Biomedika Februari 2014 Vol 5, No 2 (2013): Biomedika Agustus 2013 Vol 5, No 2 (2013): Biomedika Agustus 2013 Vol 5, No 1 (2013): Biomedika Februari 2013 Vol 5, No 1 (2013): Biomedika Februari 2013 Vol 4, No 2 (2012): Biomedika Agustus 2012 Vol 4, No 2 (2012): Biomedika Agustus 2012 Vol 4, No 1 (2012): Biomedika Februari 2012 Vol 4, No 1 (2012): Biomedika Februari 2012 Vol 3, No 2 (2011): Biomedika Agustus 2011 Vol 3, No 2 (2011): Biomedika Agustus 2011 Vol 1, No 1 (2009): Biomedika Februari 2009 Vol 1, No 1 (2009): Biomedika Februari 2009 Online First More Issue