cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota surabaya,
Jawa timur
INDONESIA
Jurnal Kimia Riset
Published by Universitas Airlangga
ISSN : -     EISSN : -     DOI : -
Core Subject : Science,
Chemistry
Arjuna Subject : -
Articles 150 Documents
 11   12   13   14   15 
ANTI-INFLAMMATORY ACTIVITY OF ETHANOL EXTRACT AND ETHYL ACETATE FRACTION OF KEBIUL (Caesalpinia bonduc L.) SEED COAT AGAINST INHIBITION OF PROTEIN DENATURATION Dwi Fitriyani; Raden Fatahillah
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.31108

Abstract

Inflammation is a normal protective reaction against tissue damage caused by physical injury, harmful chemicals, and protein denaturation. Protein denaturation is a process in which proteins lose their tertiary structure and secondary structure due to foreign substances, external compounds, such as strong acids, strong bases, organic salts, organic solvents, and heating. The purpose of this study was to determine the anti-inflammatory activity of ethanol extract and ethyl acetate fraction of the seed coat of Kebiul (Caesalpinia bonduc L.) by calculating the IC50 value of protein denaturation in the sample. The results of the phytochemical test of the ethanol extract of Kebiul seeds contained flavonoids, alkaloids, terpenoids, steroids, saponins, and tannins, while the ethyl acetate fraction only contained tannins and alkaloids. The results of the anti-inflammatory test showed that the highest percent inhibition value of sodium diclofenac, ethanol extract, and ethyl acetate fraction, respectively, at a concentration of 20 ppm was 84.8%; 84.1%; and 50%. The IC50 values ​​of sodium diclofenac, ethanol extract, and ethyl acetate fraction were 5.4 μg/mL; 9.9 μg/mL; and 13.3 μg/mL, respectively. The three samples had percent inhibition values exceeding 20% which indicated that all three can be used as an anti-inflammatory.   Keywords: anti-inflammatory, protein denaturation, Caesalpinia bonduc L.
PURIFICATION OF ETHANOL BY CONTINUOUS ADSORPTION METHOD USING ZEOLITE 3A AND CALCIUM OXIDE Mukhtar Anas Ibrahim; Muhammad Hafizh Musyaffa; Heriyanto; Haryadi
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35682

Abstract

The depletion of oil reserves and the increasing need for fuel have become a problem in the supply of energy sources. One of the efforts to maintain the availability of fuel is to use ethanol fuel grade as an alternative fuel. Continuous adsorption is one method that can purify ethanol up to a concentration of 99.5% (v/v). This study aims to increase the purity of ethanol using adsorbent zeolite 3A and calcium oxide (CaO) with a continuous adsorption method. The feed used is technical ethanol with a concentration of 96% (v/v). The equipment used is a continuous adsorption apparatus with a fixed bed column. Parameters measured during the process were ethanol concentration, feed flow rate, temperature, and pressure. Variations carried out were variations in feed flow rate (5 mL/min, 12 mL/min, and 18 mL/min) and the type of adsorbent (zeolite 3A and CaO). The best continuous adsorption process at 5 mL/min flow rate using zeolite 3A adsorbent with the ethanol product concentration rated up to 99.54% on pycnometer analysis and 99.33% on GC-MS analysis. While using CaO adsorbent, the best results were obtained at 5 ml/min rate, with the highest ethanol product concentration of 99.54% in the pycnometer and 99.33% on GC-MS.
UTILIZATION OF ANTHOCYANIN IN EDIBLE FILM AS COCONUT MILK FRESHNESS INDICATOR: English Utary Nur Rachmani Fauzan; Astrinida Rizkina Dwi Pancani; Fitria Yulistiani; Nancy Siti Djenar
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35706

Abstract

Technology in smart packaging continues to evolve, one of which is packages equipped with food freshness indicators to monitor food safety and quality. These indicators can be formed by immobilizing anthocyanin into edible film and then changing its color to pH changes.  The research aims to determine the immobilization time, test the color stability of the edible film indicator to temperature changes, determine the characterizations of the edible film indicator based on the %relative standard deviation (%RSD) value, and apply the edible film indicators as coconut milk freshness indicators. The best immobilization time was in the 90th minute with %RSD=0%. The edible film indicators did not change color from 10 to 50°C with %RSD=0%. The characterizations of edible film indicators on pH 6, 7, 8, and 10 had response times of 6.68 minutes; 9.49 minutes; 3.57 minutes; and 4.37 minutes; periods of 14 days, 13 days, 14 days, and 16 days; and good reproducibility at pH 6 and 10 and not good at pH 7 and 8. Overall, based on anthocyanin color changes, an edible film indicator can be used as a freshness indicator in coconut milk but cannot indicate the pH value of coconut milk.
THE EFFECT OF SULFURIC ACID CONCENTRATION ON NICKEL RECOVERY FROM LATERITE ORE BY USING ATMOSPHERIC ACID LEACHING METHOD Althafa Muntaqin; Lutfiah Rahmasari; Ninik Lintang Edi Wahyuni; Rony Pasonang Sihombing
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35712

Abstract

The processing of laterite ore by pyrometallurgy requires high temperatures whereas the Atmospheric Acid Leaching (AAL) method can be performed below 100 ℃ although its nickel recovery is inconsistent. This research aims to determine the effect of sulfuric acid concentration on nickel recovery and to determine nickel recovery after extract purification by precipitation of non-nickel metals. AAL was performed with an operating temperature of 95 °C, an operating time of 5 hours, an ore-to-solvent ratio of 0.05 g/ml, a particle size of ± 200 mesh, and sulfuric acid concentration variation of 0.2–1 M. Iron precipitation was completed with a pH variation of 0.5–3.8 by the addition of ammonia. The result showed that the concentration of sulfuric acid increased nickel recovery. The nickel recovery reached 96.43% at a concentration of sulfuric acid of 1 M. Furthermore, after extract purification, nickel recovery reached 50.61%, which was achieved at an optimum pH of 3.2.
THE UTILIZATION OF BLOTONG, MOLASSES, BRAN, AND COCONUT HUSK INTO COMPOST USING MOL OF STALE RICE AND Trichoderma sp. Hilda Fitria Nurul Huda; Putri Fakhirah Ramadhani; Endang Kusumawati; Mukhtar Ghozali
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35714

Abstract

Compost is a solution for dealing with organic waste. Compost with organic material must be mixed according to its elemental composition. Protein and potassium are obtained from bran and coconut husk. Blotong contains phosphorus (P), while molasses contains total N and K2O. Local Microorganisms (MOL) of stale rice is an activator to increase the microbiological decomposition of organic matter and contains Saccharomyces cerevisiae, Bacillus cereus, and Aspergillus sp. The addition of Trichoderma sp. can speed up the composting process. The aim of the study is to determine the effect of adding Blotong and bran on the quality of compost, to obtain the most effective composition of Blotong, molasses, bran, and coconut husk for composting using MOL activator of stale rice and Trichoderma sp. according to SNI 7763:2018, and to determine the most effective composting time. The ratio of Blotong, coconut husk, bran, and molasses for the three variations were 56:10:30:4; 66:10:20:4; and 76:10:10:4 in percent as much as 6 kg calculated with Takakura method. The result of the study showed the three variations had fulfilled SNI 7763:2018 in 18 days, with the most effective composition is the 3rd variation.
FORMULATION AND EVALUATION OF SEA GRAPE (Caulerpa racemose) EXTRACT AS HAND CREAM AND ITS ANTIOXIDANT ACTIVITY TEST Septilina Melati Sirait; Tita Rosita; Lintannisa Rahmatia
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35889

Abstract

Caulerpa racemosa (C. racemosa) is a seaweed containing folic acid, thiamine, ascorbic acid, and phenol as secondary metabolites that function as antioxidants. This study aims to formulate a hand moisturizing cream containing C. racemosa extract and evaluate the quality of the cream preparation. The manufacture of hand cream from C. racemosa extract was carried out in several stages, namely C. racemosa extraction, antioxidant testing, formulation of cream preparations, and evaluation. Evaluation of hand cream preparations of C. racemosa extract included organoleptic tests, homogeneity, pH measurement, viscosity, spreadability, and adhesion. The yield of C. racemosa from the extract was 33%. The IC50 of the C. racemosa extract was 159.8 ppm. The results of the organoleptic test of hand cream preparations showed physical characteristics in terms of pH, viscosity, homogeneity, dispersibility, and adhesion following the requirements of cosmetic preparations from the Directorate General of BPOM.
MOLECULAR DOCKING COMPOUNDS IN METHANOL EXTRACT OF MANGO LEAVES (Mangifera indica L.) AS ANTI-INFLAMMATORY AGENT Vina Juliana Anggraeni; Purwaniati Purwaniati; Wempi Budiana; Thoriq Nurdin
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35950

Abstract

Previous studies have shown that mango has anti-inflammatory properties. Anti-inflammatory drugs are compounds or medicines used to treat diseases caused by inflammation. The most commonly used anti-inflammatory drug is a non-steroidal anti-inflammatory drug (NSAID). The drug works by inhibiting the enzyme cyclooxygenase (COX). The purpose of this study was to determine the profile metabolites present in the methanol extract of mango leaves and their interaction with the COX enzyme. This study includes an analysis of the compounds contained in the methanol extract of mango leaves using LCMS / MS and molecular docking studies of these compounds. Compounds detected by MS include C26H24O14, C45H84O14, Khellol-β-D-glucoside, Mangiferin, and Nevadensin-5-β-D-glucoside. Analysis of docking result was based on ΔG and Ki and the binding interactions that occur. Compounds that are compatible with COX1 and COX2 are Khellol βD glucoside with G and Ki values of 7.49 kcal/mol and 3.23 µM and 8.32 kcal/mol and 0.7919 µM, respectively. Through the molecular docking process, it was confirmed that khellol β-D-glucoside may be activated as an anti-inflammatory agent.  
EFFECT OF CATALYST PROPERTIES ON THE DEOXYGENATION REACTION OF VEGETABLE OIL AND MODEL COMPOUND TO PRODUCE DIESEL RANGE HYDROCARBON FUELS: A REVIEW Reva Edra Nugraha; A. R. Yelvia Sunarti; Hellna Tehubijuluw; Zuhriah Mumtazah
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.35974

Abstract

The concern associated with the depletion of fossil fuel energy has opened up windows of opportunity for researchers to develop potential energy from renewable resources. The renewable green diesel with diesel range hydrocarbon structure has gained increasing popularity by removing oxygen molecule via direct or hydrodeoxygenation (HDO) and indirect or deoxygenation (DO) reaction.  The catalyst design is an important key to achieve the high quality of diesel range hydrocarbon fuels. The different catalyst properties effect to the distribution of deoxygenated liquid product, the catalytic activity and coke formation during the reaction process. The interaction between metal and support catalyst causes electron transfer to give the synestistic effect. The acidity and basicity play important role in C-C and C-O breaking bond in triglyceride and prevent the coke formation. The pore structure and pore size catalyst provide the accessibility of active sites alleviates the diffusion limitation of reactants/ products.
FORMULATION AND EVALUATION OF ANTI-INFLAMMATORY EMULGEL OF Brucea javanica (L.) Merr SEED EXTRACTS Handa Muliasari; Diva Almira; Windah Anugrah Subaidah
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.36010

Abstract

Anti-inflammatory drugs are needed to overcome excessive inflammatory reactions that can interfere with activities. The existence of side effects in the use of synthetic anti-inflammatory drugs causes the search for natural drugs with high therapeutic effects and low side effects to continue. Seeds of Makassar (Brucea javanica (L.) Merr) plant are known to have anti-inflammatory activity. Topical anti-inflammatory administration is currently being developed because it can minimize side effects compared to oral. This study aimed to formulate 96% ethanol extract of Makasar fruit seeds in the form of an emulgel and to determine the physical properties and anti-inflammatory activity of the emulgel in vitro. Makasar fruit seeds were extracted by sonication method using 96% ethanol solvent (3 x 35 minutes). The extract was then formulated into an emulgel preparation with an extract concentration of 1%. Emulgel was then tested for its physical properties and anti-inflammatory activity in vitro using protein denaturation inhibition method. The results showed that the physical properties of emulgel base (F0), extract emulgel (F1), and Na-diclofenac emulgel (F2) met the requirements for homogeneity, pH, adhesion, spreadability, and viscosity tests. F0, F1, and F2 had inhibition percentages of 3.74±1.58%,; 23.07±0.72%; and 33.49±0.29, respectively. According to one-way ANOVA statistical test, the three tested groups had significant differences.
THE EFFECT OF CHEMICAL AND MICROWAVE HEATING TREATMENT FOR REDUCING SUGAR RECOVERY Yulia Tri Rahkadima; Medya Ayunda Fitri
Jurnal Kimia Riset Vol. 7 No. 1 (2022): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v7i1.36189

Abstract

Microwave heating treatment was the one type of pretreatment process used in the manufacture bioethanol because it can be applied singly or in combination with other chemicals. The purpose of this study was to determine the effect of microwave heating on the pretreatment process using acid and alkaline solvents. The research was carried out in two stages, namely the preparation of raw materials and pretreatment with microwave. At the stage of preparation of raw materials, bagasse was dried for 2 days and then crushed to a size of 50 mesh to uniform the size of the raw materials. The raw materials that have been prepared are then subjected to a pretreatment process. The pretreatment process was carried out using a modified microwave with temperature settings and the addition of a stirrer. 5 grams of bagasse powder and 200 ml of a solution of H2SO4 or NaOH (0.2 M, 0.4 M, and 1 M) were put into a round tool flask and then put into the microwave. Pretreatment was carried out at 180°C with time variables of 10, 15, 20, 25, and 30 minutes. Then the solution was separated from the residual solid by filtration and the solution was neutralized with 1 M HCl. The results showed that the use of acidic and alkaline solvents, high concentrations of solvents can lead to smaller the acquisition of reducing sugars in the liquid product phase. The highest percentage of reducing sugar obtained is 0.559% when using an acid solvent with a concentration of 0.1 M for 20 minutes.

Page 13 of 15 | Total Record : 150

 11   12   13   14   15 

Filter by Year

2016 2023


Reset
Filter By Issues
All Issue Vol. 8 No. 1 (2023): June Vol. 7 No. 2 (2022): December Vol. 7 No. 1 (2022): June Vol. 6 No. 2 (2021): Desember Vol. 6 No. 1 (2021): Juni Vol. 5 No. 2 (2020): Desember Vol. 5 No. 1 (2020): Juni Vol. 4 No. 2 (2019): Desember Vol. 4 No. 1 (2019): Juni Vol. 3 No. 2 (2018): Desember Vol. 3 No. 1 (2018): Juni Vol. 2 No. 2 (2017): Desember Vol. 2 No. 1 (2017): Juni Vol. 1 No. 2 (2016): Desember Vol. 1 No. 1 (2016): Juni More Issue