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Nusantara Medical Science Journal
Published by Universitas Hasanuddin
ISSN : 24609757     EISSN : 25977288     DOI : -
Core Subject : Science,
Materials Science & Nanotechnology Neuroscience
Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical problems and molecular mechanisms. Subjects suitable for publication include, but are not limited to the following fields of Cardiovascular; Allergy and immunology; Cancer and stem cells; Endocrinology; Gastroenterology; Tropical and Infectious Disease; and Internal medicine.
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Articles 87 Documents
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KNOWLEDGE OF DIABETIC RETINOPATHY AMONGST TYPE II DIABETES MELLITUS PATIENTS IN DR. WAHIDIN SUDIROHUSODO HOSPITAL Nursyamsi Nursyamsi; Habibah Setyawati Muhiddin; Gonardy Jennifer
Nusantara Medical Science Journal Volume 3 No. 2 Juli - Desember 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i2.5777

Abstract

Introduction: Diabetic retinopathy (DR) is the leading cause of blindness that rises significantly each year  along with the increasing diabetic population. It is estimated that 1 out of 3 people with diabetes will suffer from DR and 1 in 10 of them will be threatened with blindness. The main problem on DR management is the delay in diagnosis since most patients in the early stages do not experience visual impairment.Methods: Descriptive research was conducted over three months on 175 patients diagnosed with type 2 Diabetes Mellitus (DM) within the Internal Medicine Clinic at Hasanuddin University Hospital. Self-administered questionnaires were used to assess knowledge of DR amongst the diabetic patients.Results: The level of DR knowledge among type 2 DM was split into three categories. The level of knowledge on DM complication was within the good category for 109 patients (61.6%), whilst the level of knowledge on DR screening was within the the sufficient category for 150 patients (84.7%) and knowledge on DR management was within the good category for 98 patients (55.4%). Although the level of knowledge was categorized good for the majority of respondents, the remaining 45 (25.4%) respondents had never done DR screening, and most patients (57.1%) believed that DM patients tend not to screen due to the lack of knowledge about DR.Conclusion: In general, patients with type 2 DM have a good level of knowledge about diabetic retinopathy.
FACTORS INFLUENCING CONTRACEPTIVE UTILIZATION IN POSTPARTUM IN MOTHER AND CHILD HOSPITAL SITI FATIMAH MAKASSAR Ghaisani Humairah
Nusantara Medical Science Journal Volume 3 No. 1 Januari - Juni 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i1.5772

Abstract

Introduction : Postpartum contraception is defined as utilization of contraceptive within 42 days after a labor to prevent close interval of pregnancy. After a live birth, WHO recommended interval before attempting the next pregnancy is at least 24 months in order to reduce the risk of adverse maternal, perinatal, and infant outcomes. Several factors influence maternal in utilizing contraception after giving birth. Objective : To recognize factors influencing contraception utilization in postpartum period in Mother and Child Hospital Siti Fatimah Makassar. Study Method : The study was observational analytic study with cross sectional method. Seventy respondents were obtained with consecutive sampling technique. Chi square test was used to determine linkage value. Result : The result showed that factors affecting contraception utilization in postpartum period in Mother and Child Hospital Siti Fatimah Makassar were knowledge about contraception (p value 0.000, OR = 24.5 (2.995 – 200.437)), number of children (p value 0.004, OR = 4.182 (1.541 – 11.347)), education (p value 0.002, OR = 4.915 (1.770 – 13.646)), and husband encouragement (p value 0,000 ,OR=6,240 (2,211-17,608)). Resources variable was not related to this study. The most affecting variable was knowledge about contraception. Conclusion : Factors influecing contraception utilization in postpartum period were knowledge about contraception, number of children, education, and husband encouragement. The most affecting factor was knowledge about contraception. The most affecting factor is knowledge about contraception.
ANALYSIS FACTORS OF PSYCHOSOCIAL STRESS IN PREGNANCY Elizabet Catherine Jusuf
Nusantara Medical Science Journal Volume 3 No. 2 Juli - Desember 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i2.5775

Abstract

The Pregnancy period begins from conception until birth. It is hard to figure out if the pregnancy will get any problem. The process will involve emotional, physical and social alteration in the family. Until now,the maternal emotional condition, psychosocial stress are rarely to watch over by medical practisioners meanwhile at some study said that maternal psychosocial stress influence the outcome of baby. The aim of this study to analyze some factors that is associated to psychosocial stress in pregnancy women. This was a cross-sectional study of collected by using questionaires, were comprised of 11 questions using likert-scales, then using bivariat analysis by t-test and chi square to evaluate the sample characteristic at teaching hospital Hasanuddin University in 2015. There are 158 pregnant woman,  shows who are in the age of 26,25 ± 6,319, suffer from stress, who are in their gestasional age of 30,63 ± 9,164 weeks will be going through the high level of stress. The age of pregnant women and their gestasional age in this study do not influence significantly toward psychosocial stress. Social economic factors such as level of education, occupation, and parity influence the pregnant women psychosocial stress level.
THE CORRELATION BETWEEN EPICARDIAL FAT THICKNESS BASED ON MULTI SLICE COMPUTED-TOMOGRAPHY SCAN THORAX WITH WAIST CIRCUMFERENCE AND BODY MASS INDEX ON DYSLIPIDEMIA NON-DIABETES MELLITUS SUBJECT Yenny Wendy; Mirna Muis
Nusantara Medical Science Journal Volume 3 No. 1 Januari - Juni 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i1.5774

Abstract

Introduction : Epicardial fat is visceral fat that plays a role in cardiovascular disease. Dyslipidemia non-diabetes mellitus can be found in both obese and non-obese patients. Measurement of waist circumference and BMI can assess central and peripheral obesity. The study aims to finding out the correlation between epicardial fat thickness based on MSCT scan Thorax with waist circumference and BMI on dyslipidemia non-diabetes mellitus subject. Method: There were 57 research samples of 28 to 70 years old who had dysfunction lipid profile. The most samples were found in the age group of 45-64 years with epicardial fat ranges from 2.80 to 10.80 mm and mean of 6.37 mm. Data were analysed by Mann-Whitney and Spearman correlation test. Result: There was a significant correlation between waist circumference and epicardial fat (r = 0.286, p = 0,031). There was no difference in mean of epicardial fat thickness by sex. There was no correlation between sex, and BMI with epicardial fat. Conclusion: There is a correlation between waist circumference and epicardial fat that may be affected by several factors in patients with dyslipidemia non-diabetes mellitus.
THE EFFECT OF FREELETIC SPORT TO VO2 MAX LEVELS ON THE FREELETIC COMMUNITY MEMBERS IN MAKASSAR CITY Irianto Irianto; Hasnah Hasnah
Nusantara Medical Science Journal Volume 3 No. 2 Juli - Desember 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i2.5776

Abstract

Introduction: VO2 max is the maximum oxygen amount of  that can be consumed during intense physical activity until eventually fatigue occurs. A person with a good  level of VO2 max means having good physical fitness as well. Physical fitness gives the ability to a person to do daily productive work in the absence of excessive fatigue. The low one cardiorespiratory fitness may incrase the risk of death from heart disease and hypertension. Giving freeletic exercise is one of the techniques used to improve cardiorespiratory fitness or VO2 max. Methods: This research is Pre-experimental research with one group pre-post test design. The sample of the study amounted to 20 people and freeletic exercise was given 12 times. The measuring tool used is Multistage Test of Fitness / Beep Test to know the level VO2 max  of sample  before and after freeletic sporting practice. Results: The results of this study indicate that 17 respondents experienced a significant increase in VO2 max and 3 other respondents did not experience improvement by giving 12 times freeletic sports exercise. Conclusion: Based on Paired T test to know whether or not there is influence, it can be concluded that there is influence of giving freeletic sport to max VO2 level on freeletic community member after given 12 times (p< 0,001, p<0,05) freeletic sport practice.
THE DIFFERENCE HUMAN LEUKOCYTE ANTIGEN-E (HLA-E) EXPRESSION AND NATURAL KILLER CELLS (NK CELLS) IN TROPHOBLAST BETWEEN INTRAUTERINE GROWTH RESTRICTION (IUGR) AND NORMAL PREGNANCY soetrisno soetrisno; Sri Sulistyowati; Supriyadi Hari Respati; Bambang Triono Cahyadi
Nusantara Medical Science Journal Volume 3 No. 1 Januari - Juni 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i1.5781

Abstract

Background: Intrauterine growth restriction (IUGR) is still a major cause of perinatal morbidity and mortality. IUGR incidence ranged from 4.4 to 6.44% of pregnant women. Human Leukocyte Antigen - E and NK cells are thought to play an important role towards the process of IUGR.Objective: To determine aetiopathogenesis HLA-E expression and NK Cell in IUGR.Methods: An analytical observational study conducted through a cross-sectional approach. The research was conducted on March-October 2015 at the Obstetrics and Gynecology Department, Dr. Moewardi Hospital Surakarta and at of Laboratory of Pathology, Faculty of Medicine, Universitas Sebelas Maret Surakarta. Subjects who meet the inclusion and exclusion criteria consisted of 20 patients with IUGR and 20 normal pregnant patient. The researcher examined HLA-E Expression and NK cells in trophoblast using immunohistochemical method and statistical analysis using t test.Results: The average HLA-E expression in the trophoblast in IUGR group 17.80 ± 5.55, compared with normal pregnancy 66.23 ± 19.83, p value = 0.0001 (p <0.05). The average expression of NK cells in trophoblast in IUGR group 137.71 ± 28.09 compared with normal pregnancy 31.75 ± 14.77, p value = 0.0001 (p <0.05).Conclusion: HLA-E expression in normal pregnancy trophoblast is higher than pregnancies with IUGR. Expression of NK cells in pregnancy with IUGR is higher compared with normal pregnancy.
PERBEDAAN KADAR NITRIC OXIDE PADA IBU HAMIL TRIMESTER 1 DENGAN ANEMIA DAN TIDAK ANEMIA Yadul Ulya; Aryadi Arsyad; Saidah Syamsuddin
Nusantara Medical Science Journal Volume 3 No. 2 Juli - Desember 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i2.5779

Abstract

Anemia saat hamil berefek buruk bagi ibu maupun janin, karena dapat mengurangi suplai oksigen pada metabolisme ibu akibat kekurangan kadar hemoglobin untuk mengikat oksigen, dan peran hemoglobin sebagai pengikat nitric oxide dapat menyebabkan vasokontriksi dan mempengaruhi pengiriman oksigen. Tujuannya untuk mengetahui perbedaan kadar nitric oxide pada ibu hamil trimester 1 dengan anemia dan tidak anemia. Desain penelitian cross sectional study dengan masing-masing 35 ibu hamil trimester 1 yang anemia dan tidak anemia dengan teknik consecutive sampling. Hasil penelitian menunjukkan rata-rata kadar nitric oxide pada ibu hamil trimester 1 yang anemia lebih tinggi (128,8μmol/L) dibandingkan yang tidak anemia (89,1μmol/L) nilai p=0,008. Ibu hamil trimester 1 yang anemia kemungkinan 3,692 kali memiliki resiko mengalami peningkatan kadar nitric oxide dibandingkan yang tidak anemia dengan cut off point 92,86μmol/L. Disimpulkan, kadar nitric oxide lebih tinggi pada ibu hamil trimester 1 yang anemia dan memiliki resiko terjadi peningkatan kadar nitric oxide pada ibu hamil trimester 1 dengan anemia sebesar 3,962 kali.
ELEVATED UNCONJUGATED BILIRUBIN IN SCHIZOPHRENIC PATIENTS Ilhamuddin Aziz; Yuyun Widaningsih; Rosdiana Natzir; A. Jayalangkara Tanra
Nusantara Medical Science Journal Volume 3 No. 1 Januari - Juni 2018
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v3i1.5780

Abstract

Strategies for schizophrenic treatment still have been developed in order to increase their effectively, based on latest findings in the etio-pathology. Coincidence of hyperbilirubinemia, especially related to Gilbert’s Syndrome (GS), and schizophrenia/other psychiatric disorders, was reported in several studies although the pattern of this alteration is still controversial.  Bilirubin could induce microglia to release pro-inflammatory cytokine that cause neuroinflammation, one of hypothetic etio-pathogenesis has been the most extensively studied recently. However, no data have been presented about this phenomenon in Indonesia. Therefore, this study aims to investigate plasma bilirubin concentration in psychotic spectrum.This study is cross sectional design that we examined both the total bilirubin and direct bilirubin of every psychotic patient admitted for the first time to Rumah Sakit Khusus Daerah (RSKD) Provinsi Sulawesi Selatan over a period of July—December 2012, by using health people as control. Diagnostic determination was set based on International Classification of Diseases (ICD) 10. Patients suffering from any disease such as anemia (decreased hemoglobin), liver diseases (elevated liver enzymes), or substance abuse were excluded.            From 73 samples, we found that plasma UCB level was significantly elevated, higher in psychotic patients, especially schizophrenic group, than in the control. Total bilirubin rate was slightly increased in schizophrenic group compare to the others and two samples in this group showed hyperbilirubinemia. Further investigations are needed to ensure that whether the elevated UCB was related to GS and whether this condition has inflammatory effect.
ANALYSIS RISK FACTORS FOR NECK PAIN COMPLAINTS IN PRODUCTION WORKERS AT PT MARUKI INTERNATIONAL INDONESIA Naurah Nadhifah; Irianto Irianto; A. Besse Ahsaniyah
Nusantara Medical Science Journal Volume 4 No. 1 Januari - Juni 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i1.6590

Abstract

Intorduction: The current most frequent health problem is Musculoskeletal Disorder (MSDs), which is pain in the neck muscles. Neck pain is a complaint taken at the back of the upper spine or cervical. Many factors affect neck pain. This study aims to determine the relationship of each risk factors with neck pain.Methods: This research was a descriptive cross sectional study involving 43 respondents based on the purposive sampling method. Risk factors taken were age, sex, years of service, work attitude, equality of shoulder height, and work posture measurements using Hand Arm Risk-Assesment Method (HARM)) and using the Visual Analog Scale (VAS) to assess the level of neck pain.Results: Data analysis using spearman with a value of p < 0.05 for years of service and work posture and the others factors with a value of p > 0.05 for sex, age, work attitude and equality of shoulder height that showed there was not significant relationship between gender, age, work attitude and equality of shoulder height with neck pain.Conclusion: There was a significant relationship between years of service and work posture with neck pain and there was not significant relationship between gender, age, work attitude and equality of shoulder height with neck pain.
HUBUNGAN PENGETAHUAN DAN PERILAKU PASIEN TENTANG PENATALAKSANAAN DIABETES MELLITUS DI BANJARBARU KALIMANTAN SELATAN Rika Meldy Agustina; Noor Diani; Agianto Agianto
Nusantara Medical Science Journal Volume 4 No. 1 Januari - Juni 2019
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v4i1.5955

Abstract

Introduction: In patients with type 2 diabetes mellitus (DM), sufficient knowledge and behavior are important for adherence to the lifelong treatment. The aim of this study is to measure the correlation between knowledge and behavior about the treatment of DM in diabetic patients in Kelurahan Cempaka.Methods: This is a cross-sectional study using a simple random sampling technique, with a total of 60 participants. We used a questionnaire on patients’ knowledge and behavior pertaining the treatment of type 2 DM.Result: From this study, we found that there is a significant correlation between knowledge and behaviour regarding the treatment in patients with type 2 DM (p<0.001).Conclusion: Knowledge has an important role in tailoring people’s behavior to carry out appropriate treatment in order to optimize the health status.

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