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All Journal BALI MEDICAL JOURNAL (BMJ) CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Kimia (Journal of Chemistry) E-Jurnal Medika Udayana Bumi Lestari PROSIDING CSGTEIS 2013 Knowledge Engineering and Data Science Matrix : Jurnal Manajemen Teknologi dan Informatika Indonesian Journal of Chemistry WIDYA LAKSANA Aptisi Transactions on Technopreneurship (ATT) ISM (Intisari Sains Medis) : Jurnal Kedokteran Literasi : Jurnal Ilmu Pendidikan Just TI (Jurnal Sains Terapan Teknologi Informasi) Jurnal Pijar MIPA Joong-Ki : Jurnal Pengabdian Masyarakat Dharma Jnana Journal of Global Pharma Technology IJRETINA - International Journal of Retina Joong-Ki

Ida Bagus Putra Manuaba

Program Studi Kimia, Fakultas MIPA Universitas Udayana, Bali-Indonesia

Author-ID : 314525

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Physics Public Health Social Sciences Other

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Betel Leaf Extract (Piper betle L.) Antihyperuricemia Effect Decreases Oxidative Stress by Reducing the Level of MDA and Increase Blood SOD Levels of Hyperuricemia Wistar Rats (Rattus norvegicus) Sumarya, I M.; Adiputra, N.; Sukrama, I D. M.; Manuaba, Ida Bagus Putra
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

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Background: Betel leaf extracts (Piper betle L.) antioxidant activity and enzyme inhibitors of XO. Hyperuricemia cause oxidative stress by increasing the formation of reactive oxygen species (ROS) cause lipid peroxidation and oxygenation of low-density lipoprotein cholesterol (LDLc). Objective: The aim of this research was to determine the betel leaf extract as an anti hyperuricemia that can lower the blood uric acid levels and oxidative stress by lowering the levels of MDA and increase the SOD of hyperuricemia of the rat’s blood. Method: Experimental research was conducted with the design of The Randomized Post Test Only Control Group Design, on normal Wistar rats (Rattus norvegicus), administered with oxonic potassium (hyperuricemia) and the hyperuricemia rats either given betel leaf extract and allopurinol. After the experiment of uric acid levels, MDA and SOD in rat blood determined. Results: The results showed that the betel leaf extract significantly (p <0.05) lower uric acid levels, MDA and increase levels of SOD in rat blood. There is a positive correlation between the levels of uric acid with MDA levels and a negative correlation, although not significantly with SOD (p >0.05). Conclusion: It can be concluded that the betel leaf extract as an anti-hyperuricemia can lower the uric acid levels and decreases oxidative stress by lowering the levels of MDA and increasing the SOD.

Gaharu Leaf Water Extract Reduce MDA and 8-OHdG Levels and Increase Activities SOD and Catalase in Wistar Rats Provided Maximum Physical Activity Parwata, I Made Oka Adi; Manuaba, Ida Bagus Putra; Sutirtayasa, I Wayan Putu; Wita, I Wayan
BALI MEDICAL JOURNAL Vol 5 No 3 (2016)
Publisher : BALI MEDICAL JOURNAL

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Background: Oxidative stress occurs due to an imbalance of the number of free radicals by the number of endogenous antioxidant produced by the body i.e. Superoxide Dismutase (SOD), Gluthathione Peroxidase (GPx), and Catalase. The imbalance between the number of free radicals and antioxida nts can be overcome with the end ogenous antioxidant intake that exogenous oxidative stress can be reduced. O ne of exogenous antioxidants is natural Gaharu leaf water extract. Objective: This research focus on the effect of Gaharu leaf water extract in reducing MDA and 8- OHdG and increase the activity of SOD and Catalase. Methods: This study was an experimental with post only controls group design. Experiment was divided into 5 groups of w istar rats, each consisting of 5 animals, i.e. negative control group without extract [K (-)], treatment 1 treated 50 mg/ kg BW/day of the extract (T1), treatment 2 treated 10 0 mg/ kg BW/day of the extract (T2), treatment 3 treated 200 mg/ kg BW/day of the extract (T3), and positive control group [K (+)] treated with vitamin Cat a dose 50 mg/ kg BW/day. All groups treated for 10 weeks. Every day, before treatment, each group was given a maximum swimming activity for 1.5 hours for 10 weeks. ELISA was used to measure MDA, 8-OHdG, SOD , and C atalase activities . Result: The research results showed that treatment of extract of leaves of Gaharu with an higher dose from 50 mg/kg BW up to 200 mg/ kg BW significantly decline (p

FITODEGRADASI DENGAN TANAMAN PACING (Speciosus Cheilocostus) UNTUK MENURUNKAN KANDUNGAN Pb, Cd Dan Hg LIMBAH CAIR LABORATORIUM Ni Nyoman Trisnawati; Ida Bagus Putra Manuaba; Iryanti Eka Suprihatin
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 4 No 1 (2016)
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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ABSTRAK: UPT. Laboratorium Analitik Universitas Udayana menghasilkan limbah yang mengandung bahan-bahan kimia berbahaya. Sistem pengolahan air limbah yaitu fitodegradasi, menggunakan tanaman Pacing (Cheilocostus speciosus) telah dicoba untuk mengolah limbah cair laboratorium. Konstruksi unit pengolahan terdiri dari sebuah bak terbuat dari beton dengan media tanah berukuran 7 m x 1,2 m x 0,34 m yang ditumbuhi Pacing. Penelitian dilakukan selama dua minggu meliputi penelitian eksperimental, observasi pre dan post perlakuan. Efektivitas sistem fitoremediasi dalam menurunkan kandungan Hg adalah 100% pada hari ketiga, Cd sebesar 77,17 % dan Pb sebesar 9,50 % pada hari keempat. Kandungan Pb, Cd dan Hg berkurang secara signifikan setelah fitoremediasi. ABSTRACT: UPT Analytical Laboratory of Udayana University produced liquid waste which contained dangerous chemicals such as : lead (Pb), Cadmium (Cd), and Mercury (Hg). Processing system of liquid waste using phytodegradation of pacing plant (Cheilocostus speciosus) has been studied to reduce the concentrations of heavy metals of laboratory liquid waste. The construction of the processing unit consisted of conerete tank filled with soil media grown over with pacing plant. The size of the tank was; 7 meters in length, 1.2 meters in width and 0.35 meters in depth. The duration of the experiment was 2 weeks, by observation of pre and post treatment to record the effectivenesss of the pacing plants in reducing the concentrations of Pb, Cd and Hg in liquid waste. The results showed the effectiveness of the system in reducing the concentration of Pb, Cd and Hg were 9,50 %; 77,17 % and 100 % respectively. The concentration of Pb, Cd and Hg decreased significantly after treatment.

RASIO ASAM NITRAT DAN SULFAT DALAM ANALISIS LOGAM KADMIUM, TEMBAGA, BESI, DAN TIMBAL PADA LIMBAH CAIR MENGGUNAKAN ICPE Ida Bagus Made Asmara Dwipa; Iryanti Eka Suprihatin; Ida Bagus Putra Manuaba
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 7 No 1 (2019): Volume 7, Nomor 1, 2019
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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ABSTRAK: Penggunaan bahan kimia yang efisien dalam proses analisis sangat menarik dan perlu untuk dikembangkan. Pada penelitian ini dipelajari penggunaan variasi rasio asam nitrat dan sulfat dalam proses destruksi basah untuk analisis logam Cd, Cu, Fe dan Pb dalam limbah cair. Berdasarkan penelitian yang dilakukan, dapat disimpulkan volume yang ditambahkan untuk memperoleh hasil paling baik adalah 1,5 mL asam nitrat dan 0,5 mL asam sulfat untuk logam Cd, Cu, dan Pb, dan 2,0 mL asam nitrat untuk logam Fe. Dengan protokol ini maka total asam yang dapat dihemat adalah 8 mL/sampel dan mengurangi limbah cair sebanyak 40 mL/sampel. Kata kunci: Destruksi Basah, Analisis Logam, Plasma Emission Spectroscopy. ABSTRACT: Efficiency of chemical uses in the analysis process is necessary and thus needs to be developed. In this study, we investigated nitric and sulfuric acid ratio (v/v) used in wet digestion process to analyze Cd, Cu, Fe and Pb metals in waste water. The research found that the best analytical results were obtained when 1.5 mL nitric acid and 0.5 mL sulfuric acid were used for digesting Cd, Cu, and Pb metals, or 2.0 mL nitric acid for Fe. With this protocol, total acid that can be saved is 8 mL per sample and liquid waste is reduced by 40 mL per sample.

VARIASI KONSENTRASI BUAH ASAM (Tamarindus indica L.) DAN SUSU SKIM TERHADAP KUALITAS YOGHURT KUNIR ASAM Ni Putu Rahayu Artini; Ida Bagus Putra Manuaba; I Nengah Wirajana
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 3 No 3 (2015)
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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ABSTRAK: Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi buah asam (Tamarindus indica L.) dan susu skim untuk menghasilkan kualitas yoghurt sesuai dengan SNI 01-2981-2009.Rancangan percobaan yang dilakukan dalam penelitian ini adalah Rancangan Acak Lengkap (RAL) yang terdiri atas sembilan perlakuan. Yoghurt kunir asam dibuat dari variasi penambahan variasi konsentrasi Tamarindus indica L. 30%, 40%, dan 50% (b/V) dan susu skim 5%, 10%, dan 15% (b/V). Sifat fisika, kimia, dan mikrobiologi yoghurt kunir asam diamati. Dihasilkan kualitas terbaik yoghurt kunir asam dengan penambahan 30% Tamarindus indica L. (b/V0dan 15% susu skim (b/V). Dengan hasil analisis penampakan cairan kental; konsistensi homogen; rasa asam; bau khas; viskositas 89,3 cP; pH 4,85; kadar abu 1,52%; kadar lemak total 2,53%; kadar protein total 3,74%; kadar asam laktat 0,223%, kadar kurkumin 0,389%; cemaran logam Pb dan Cu serta Total Coliform dan E. coli negatif.ABSTRACT:.The objective of this research was to determinethe influence of concentrated Tamarindus indica L. and skim milk powder in producing tumuric curcumin yogurt towards its product based on SNI 01-2981-2009. The research was conducted in completely randomized design which consisted of nine treatments. The yogurt mixtures were made from a variation of 30%, 40%, and 50% of Tamarindus indica L. and addition of 5%, 10%, and 15% of skim milk powder. Physical, chemical, and microbiology properties of the turmeric curcuma yogurts were observed. The results showed the best quality of turmeric curcumin yogurt was formulated by the addition of 30% Tamarindus indica L. and 15% skim milk powder, with the results of the analysis: the appearance of a viscous fluid; homogeneous consistency; sour taste; distinctive smell; viscosity of 89.3 cP; pH of 4.85; ash content of 1.52%; total fat content of 2.53%; total protein content of 3.74%; lactic acid levels of 0.22%, curcumin content of 0,389%; however the Pb, Cu, Coliform and E. coli were not detected.

KARAKTERISASI BIODIESEL DARI MINYAK JELANTAH MENGGUNAKAN PEREAKSI BIOETANOL TETES TEBU Sagung Ngurah Mayuni; Ni Made Suaniti; Ida Bagus Putra Manuaba
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 3 No 3 (2015)
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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ABSTRAK: Biodiesel merupakan bahan bakar alternatif yang dapat disintesis dari minyak jelantah dan alkohol melalui proses esterifikasi. Penelitian ini menggunakan bahan dasar minyak jelantah dengan kadar asam lemak bebas sebesar 9,16 %, dimana alkohol yang digunakan adalah bioetanol tetes tebu. Tujuan penelitian ini adalah untuk mengkarakterisasi biodiesel hasil esterifikasi dan transesterifikasi minyak jelantah dengan hasil destilasi bioetanol tetes tebu. Metode penelitian yang dilakukan adalah menggunakan perbandingan bervariasi antara minyak jelantah dan etanol yaitu 1 : 1 (B1), 3:1 (B2), 5:1 (B3). Hasil karakterisasi biodiesel diperoleh sesuai dengan SNI berturut-turut untuk densitas B1 = 860,3, B2 = 865,3 , B3 = 866,3 (kg/m3), Viskositas B1 = 19,138 , B2 = 24,881 , B3 = 25,359(mm2/s), Titik NyalaB1 = 138,5, B2 = 93,5, B3 = 212,5 (0C). Titik tuang B1 = 6, B2 = 93,5, B3 = 212,5. Titik Tuang B1 = 6, B2 = 6, dan B3 = 9 (0C). Korosi B1 = 1a, B2 = 1a dan B3 =1a. Untuk kadar air dengan hasil B1 = 0,05, B2 = trace (tidak terdeteksi) dan B3 = 0,2 (% v/v).Biodiesel minyak jelantah dan etanol tetes tebu dapat terbentuk, setelah dianalisis dengan kromatografi gas menunjukkan adanya senyawa ester (etil palmitat, etil linoleat, etil laurat) dengan waktu retensi masing-masing adalah 17,0, 18,6 , 18,7 menit. Berdasarkan hasil penelitian disimpulkan bioetanol tetes tebu dapat digunakan dalam sintesis biodiesel. Penggunaan bioetanol tetes tebu dalam sintesis biodiesel diperoleh karakteristik sesuai dengan Standar Nasional Indonesia (SNI) -04-7182-2006 kecuali viskositas.ABSTRACT: Biodiesel is an alternative energy for fossil fuel. It can be synthesized by esterification of waste cooking oil with alcohol. In this research, the used waste cooking oil contains 9.16 % FFA, while the alcohol used was bioethanol fermented from molase. The aim of this research was to characterize biodiesel produced from esterification and transesterification of used cooking oil with bioethanol molase. The ratios of oil to bioethanol were 1:1 (B1), 3:1 (B2), and 5:1 (B3). Based on the characterizations of the biodiesel, it was found that the density were 860.3, 865.3, 866.3 kg/m3 for B1, B2, B3 respectively. The viscosities were 19.138, 24.881, 25.359 mm2/s for B1, B2, B3 respectively. The flash points were 138.50C, 93.50C, 212.50C for B1, B2, B3 respectively. The pour points were 6, 6, 90C for B1, B2, B3 respectively. The copperstrip corrosions were 1a, 1a, 1a for B1, B2, B3 respectively. The water content were 0.05, trace, 0.2 % v/v for B1, B2, B3, while B2 only contained trace amount of water. The gas chromatography analysis showed that the biodiesel produced contains ethyl palmitate, ethyl linoleate and ethyl laurate with retention time of 17.0, 18.6 , 18.7 minutes respectively. Based on the analyses, it can be concluded that biodiesel from used cooking oil and molase fulfils the Indonesian National Standard (SNI) -04-7182-2006, except for its viscosity.

PEMANFAATAN TEH KOMBUCHA SEBAGAI OBAT HIPERURISEMIA MELALUI PENURUNAN KADAR ASAM URAT DAN MALONDIALDEHID Ni Luh Putu Kartika Mardiani; Ida Bagus Putra Manuaba; I Wayan Suirta
Jurnal Kimia (Journal of Chemistry) Vol. 8, No. 2 Juli 2014
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Research has been conducted to determine the decrease in uric acid levels and malondialdehyde (MDA) of rats hyperuricemia after being given kombucha tea. The research was carried out with the draft post-test control group design. Kombucha tea with various fermentation time of 4, 8 and 12 days were given to hyperuricemia rats with doses of 10 mL/kg body weight and 40 mL/kg body weight. The results showed that kombucha tea can lower uric acid levels and MDA with the most significant decrease showed by the 8 day fermented kombucha tea with a dose of 40 mL/kg body weight. The decreases were 2.00±0.09 mg/dL and 1.68±0,34 umol/L respectively.

PEMANFAATAN TEH KOMBUCHA SEBAGAI OBAT HIPERURISEMIA MELALUI PENURUNAN KADAR 8-HIDROKSI-2-DEOKSIGUANOSIN Made Baruna Jayadilaga; Ida Bagus Putra Manuaba; Ni Luh Rustini
Jurnal Kimia (Journal of Chemistry) Vol. 8, No. 1 Januari 2014
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

The utilization of kombucha tea as hyperuricemia medicine by decreasing levels of 8-hydroxy-2-deoksiguanosin (8-OHdG) has been carried out. This study aimed to determine the ability of kombucha tea to decrease uric acid and 8-OHdG levels in hyperuricemia rats. This research is true experimental with posttest only control group design. Rats that had experienced hyperuricemia were given kombucha tea dose of 10 mL/kg body weight and 40 mL/kg body weight of 4, 8, and 12 days fermentation period. The results showed that kombucha tea can decrease uric acid and 8-OHdG levels in hyperuricemia rats. The best dose of kombucha tea in decreasing uric acid and 8-OHdG levels was 40 mL/kg body weight with 8 days fermentation period. The decrease of uric acid and 8-OHdG levels were 93.88% and 85.89% respectively.

EFEKTIVITAS LUMPUR AKTIF DALAM MENURUNKAN NILAI BOD (Biological Oxygen Demand) DAN COD (Chemical Oxygen Demand) PADA LIMBAH CAIR UPT LAB. ANALITIK UNIVERSITAS UDAYANA Yudith Rizkia Widyawati; Ida Bagus Putra Manuaba; Ni Gst Ayu Made Dwi Adhi Suastuti
Jurnal Kimia (Journal of Chemistry) Vol. 9, no. 1 Januari 2015
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

This research was conducted to determine the effectivity of activated sludge to decrease the Biological Oxygen Demand (BOD) and Chemical Oxygen Demand (COD) of waste water produced by the UPT. Lab Analitik Udayana University. This research used varied sediment masses and aeration times in order to determine the optimum conditions of activated sludge and the effectivity. Variation of the masses were 5, 10 and 20 grams and the aeration times were 1; 2; 3; 4 and 5 days. The result showed that both parameters studied decreased as a result of biological activity which oxidizes organic and inorganic compounds contained in the waste water. Five grams sediment within aeration time 4 days were the most optimum condition in decreasing the BOD (up to 75,25 %) and COD (up to 58,08 %). The results of One-way ANOVA showed there were a significant difference between BOD and COD before and after 3 , 4 and 5 days treatment.

PEMBUATAN DAN KARAKTERISASI ARANG AKTIF DARI BATANG TANAMAN GUMITIR (TAGETES ERECTA) DENGAN AKTIVATOR NaOH Emmy Sahara; Ni Kadek Dahliani; Ida Bagus Putra Manuaba
Jurnal Kimia (Journal of Chemistry) Vol. 11. No.2 Juli 2017
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Dalam penelitian ini dilakukan pembuatan dan karakterisasi arang aktif dari batang tanaman gumitir (Tagetes erecta) menggunakan aktivator NaOH. Penelitian ini bertujuan untuk membuat arang aktif dan menentukan konsentrasi NaOH optimum yang dibutuhkan untuk mendapatkan arang aktif dengan karakteristik yang baik ditinjau dari kadar air, kadar zat mudah menguap, kadar abu total, kadar karbon, daya serap terhadap metilen biru, dan daya serap terhadap iod. Hasil penelitian menunjukkan bahwa arang aktif yang diaktivasi dengan natrium hidroksida (NaOH) 2,5% menghasilkan arang aktif dengan karakteristik terbaik dan memenuhi standar baku mutu SNI 06 – 3730 – 1995 tentang arang aktif teknis. Arang aktif yang diperoleh dalam penelitian ini memiliki kadar air sebesar 1,25 ± 0,02%, kadar zat mudah menguap sebesar 12,00 ± 0%, kadar abu total sebesar 5,33 ± 0,41%, kadar karbon sebesar 81,41%, daya serap terhadap metilen biru sebesar 199,97 ± 0,07 mg/g, dan daya serap terhadap I2 sebesar 728,09 ± 2,16 mg/g. Hasil analisis dengan spektrofotometer FTIR menunjukkan bahwa arang aktif tersebut mempunyai gugus fungsi C-H alifatik, C=O, C=C aromatik, dan O-H ikatan hidrogen

Co-Authors . Elvira A. A. Bawa Putra Anak Agung Mas Putrawati Triningrat Angelina S Tallo Ari Andayani Ari Andayani Ariesanti Tri Handayani, Ariesanti Tri Atmaja, I Made Ari Dwi Suta Candra Dwipayana Hamdin Dea Emmanuel Elfrida Magdalena Manurung Emmy Sahara Ezra Naibaho Faturrahman Gede Wirya Kusuma Duarsa Gusti Ayu Putu Eka Dewi Prihantari Gusti Ngurah Sutapa I Dewa Made Sukrama I Gusti Ayu Putu Eka Dewi Prihantari I Gusti Ngurah Putra Harthawan I Ketut Agus Somia I Ketut Darma I Ketut Widiana I M. Sumarya, I M. I Made Bakta I Made Dwi Surya Wibawa I Made Oka Adi Parwata I Nengah Wirajana I Nyoman Gede Arya Astawa I Nyoman Semadi I Putu Bagus Arya Pradnyana I Putu Gde Sukarata I Wayan Budi Sentana I Wayan Eka Sutyawan I Wayan Gede Jayanegara I Wayan Putu Sutirta Yasa I Wayan Suasnawa I Wayan Suirta I Wayan Wita I. A. R. Astiti Asih Ida Ayu Anom Arsani Ida Ayu Ria Paramita Handayani Ida Bagus Made Asmara Dwipa Ida Bagus Made Suryatika Irma Nuraeni Salsabila Iryanti Eka Suprihatin Ketut Priya Premayanti Ketut Putu Yasa Ketut Suryana Ketut Tuti Parwati Merati Komang Ayu Triana Indah Komang Ayu Triana Indah Luh Gede Anggasari Dewi Made Baruna Jayadilaga Muhammad Fahmi N. Adiputra Ni G. A. M. Dwi Adhi Suastuti Ni Kadek Dahliani Ni Luh Putu Kartika Mardiani Ni Luh Rustini Ni Made Ari Suryathi Ni Made Ayu Surasmiati Ni Made Puspawati Ni Made Suaniti Ni Nyoman Trisnawati Ni Putu Rahayu Martini Poniman, S. Putu Diah Krisna Junitasari Rudi Wisaksana Sagung Ngurah Mayuni Sri Wahjuni Yudith Rizkia Widyawati

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