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Jurnal Ilmiah Kedokteran Wijaya Kusuma
Published by Universitas Wijaya Kusuma Surabaya
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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Articles 6 Documents
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Search results for , issue " Vol 4, No 2 (2015): Edisi Desember 2015" : 6 Documents clear
EFFECT OF MANGOSTEEN’S FRUIT PEEL EXTRACT TOWARD TO TOTAL CHOLESTEROL, LDL, HDL SERUM IN RATS WERE GIVEN BY USED COOKING O Raharjo, Loo Hariyanto; Monica, Monica
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Waste cooking oil causes increased level of total cholesterol and LDL and decreased level of HDL serum, which became coronary heart disease. The aim of this study was to evaluate the effect of mangosteen peels extract, which contain alpha-mangostin (xanthone) to decreased level of total cholesterol and LDL and increased level of HDL in rats exposed to waste cooking oil per oral. This study used true experimental designs with randomized post-test only control group design. This study used thirty rats were dividing into six treatment group, which control with Na-CMC 0,5%, control with extract of mangosteen pericarp at dosages of 800 mg/ kg body weight, exposed to waste cooking oil per oral, and exposed to waste cooking oil per oral with extract of mangosteen pericarp at dosages of 600, 800, and 1000 mg/kg body weight. All groups were given treatment for 12 weeks. After 12 weeks, rats were anesthetized with chloroform for collection of blood by cardiac puncture. Analysis of level of total cholesterol , LDL, and HDL serum with spectrophotometer. From Post Hoc test with Least Significant Differences it was concluded that extract of mangosteen peels can decreased level of total cholesterol and LDL and increased level of HDL serum.
ADMINISTRATION OF RED ROSELLA’S PETALS EXTRACT (Hibiscus sabdariffa) INCREASE LEVEL OF SUPEROXIDE DISMUTASE (SOD) WISTAR RATS WHICH INDUCED BY REPETEADLY HEATED COOKING OIL Herdiani, Novera; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Background:  repeatedly heated cooking oil is cooking oil that is used many times, had saturated fatty acids containing free radicals. Red rosella petals extract contains antioxidants to minimize the effects of repeatedly heated cooking oil that can raise the levels of SOD. The aim of this study was to analyzed the effect of red rosella’s petals extract against oxidative stress of Wistar rats were induced by repeatedly heated cooking oil with examine levels of  serum SOD.This research was conducted True Experimental Laboratory with a completely randomized design (CRD) and use the post test. The sample consisted of 24 male rats were divided 4 groups: negative control (fed with standard diet); positive control (fed with standard diet + administered by repeatedly heated cooking oil as much as 2.1 ml / kg bw); treatment group dose I (fed with standard diet + administered by red rosella extract dose 540 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw), and treatment group dose II (fed with standard diet + administered by red rosella extract dose 810 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw). Analysis of data using statistical test One Way ANOVA and Tukey HSD (α = 0.05).Results: There were significant differences (p = 0.000) between groups. Red rosella extract treatment group dose 810 mg / kg bw and 540 mg / kg bw were significantly different from the positive control (p = 0.000). Red rosella extract group dose 540 mg / kg bw was significantly different from the negative control (p = 0.000). Red rosella extract group dosage of 810 mg / kg bw was not differ significantly from the control group (p = 0.171).Conclusion: The red rosella’s petals extract dose of 810 mg / kg bw and dose of 540 mg / kg bw were able to prevent oxidative stress. Optimal deose of red rosella petals extract dose of 810 mg / kg bw was the most effective, because the higher antioxidant activity (67.33%) at dose 810 mg / kg bw dose than 540 mg / kg bw.
THE EFFECTS OF CORN FLOUR WITH TEMPEH FLOUR SUPPLEMENTATION FEEDING IN DIABETES MELLITUS WISTAR RATS TOWARD BLOOD GLUCOSE LEVEL Asmarani, Fatifa; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Background: Diabetes mellitus (DM) is metabolic disorder syndrome characterized by hyperglycemia due to deficiency of insulin secretion. Patients of diabetic patients increases each year, so it needs proper handling. Corn flour is a source of carbohydrates with a low glycemic index to help reduce the rise in blood sugar levels. In addition, supplementation with tempeh flour containing isoflavones act to protect cells from free radical thereby inhibiting damage cells. Fiber in tempeh affect blood glucose levels because it slows the absorption of glucose.Objective: To determine the effect supplementation of corn flour with tempeh flour on blood sugar levels in diabetes mellitus Wistar rats.Methods: The study was true experimental design with Pre-posttest control group design, samples were 20 male Wistar rats aged 2-3 months were then divided into 4 groups (T0, T1, T2, T3.) T0 was injected with alloxan as 30 mg / 150 grams of BB rats are subsequently treated with standard diet; T1 was dministered by standard diet 50% + 50% corn flour; T2 was administered by standard diet 50% + 30% + corn flour tempeh flour 20%; and T3 was administered by standard diet of corn flour 50% + 15% + 35% tempeh flour for 2 weeks. Blood glucose levels were measured with a glucose kit (GOD FS). Research data were analyzed by One Way ANOVA followed by Tukeys Post Hoc test p-value <0.05.Results: There were significant differences on blood sugar levels in all groups (p = 0.000): control group (only dietary standards), T1 (administered by standard diet 50% + corn flour 50%), T2 (administered by a standard diet 50% + cornstarch 30% tempeh flour + 20%) and T3 (administered by standard diet of corn flour 50% + 15% + 35% tempeh flour).Conclusion: corn flour with tempeh flour supplementation effect on decresing of blood sugar levels.
USE OF CLASSIFICATION AND REGRESSION TREE (CART) FOR CHRONIC PERIODONTITIS CLASSIFICATION IN DENTAL HOSPITAL OF HANG TUAH UNIVERSITY SURABAYA Maharani, Aulia Dwi
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Classification and Regression Tree (CART) is now commonly used as one of nonparametricclassification methods. The advantage of this method is it can effectively used on data whichhave many independent variables. It is also easy to be interoperated.The aim of this research is to classify Chronic Perodontitis in Dental Hospital of Hang TuahUniversity Surabaya using CART. The Chronic Periodontitis divided into 3 categories: mild,moderate, and heavy. Based on the analysis result, 2 factors can affected the mild type ofchronic periodontitis , 6 factors affected moderate type of chronic periodontitis and 8 factorsaffected the heavy type of chronic periodontitis.The criteria used to count the accuracy of the CART classification is 1-APER. The 1-APERscore shows a very good result which is 92,5% for data learning and 90% for data testing.
DESCRIPTION OF OSTEOPOROSIS RISK BASED NUTRITION STATUS IN ELDERLY AND CALCIUM INTAKE IN PUSKESMAS SIDOSERMO SURABAYA 2015 Prabawani, Yuni
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
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Background. The number of elderly in Indonesia in 2011 about 24 million people, or nearly 10% of the population. Experts projected that by 2020, life expectancy was 71.7 years with the elderly into estimates of the number of elderly 28.8 million people (11.34%). An increase in the number of elderly will cause problems in the elderly, especially the problem of degenerative diseases, one of them is osteoporosis. Prevalence rate of osteoporosis is higher so the need for vigilance. Causes Osteoporosis is multifactoral, such as unhealthy lifestyle and not exercising regularly, as well as the prevention of osteoporosis knowledge is lacking. The occurrence of Osteoporosis caused by lack consumption of calcium in Indonesian society. The purpose of this research was to describe the risk of osteoporosis by nutritional status and calcium intake in the elderly in health centers Sidosermo Surabaya 2015. Methodology This study is a descriptive study with cross sectional approach. A total of 28 elderly people (samples) with a total sampling method. Body weight was measured by digital scale, height was measured by microtoise staturemeter, Osteoporosis was assessed through the measurement of bone density by using Hologic Sahara Densitometry Quantitative Ultrasound (QUS) in the calcaneus bone, which is classified into three is normal, mild risk and high risk. Results: A total of 7 people (25%) had osteoporosis, 21 people had osteopenia (75%). Twelve have a normal body mass index, and 16 had abnormal body mass index. Calcium intake in 8 people (28,6%) had enough calcium intake and 20 people (71,4 %) had low calcium intake.Conclusion: The incidence of osteoporosis in the Health Center Sidosermo Surabaya occurred in elderly with abnormal BMI and inadequate calcium intake.
EFFECT OF FLUORIDE SOLUTION ON SALIVARY AMYLASE ACTIVITY Willianti, Enny
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Fluoride has the benefit on the tooth to inhibit caries. Fluoride is systemically incorporated into the crystal lattice of enamel by exchanging positions with the hydroxyl ion to result in formation of fluorapatite. Fluoride used locally may inhibit tooth demineralization, one of the mechanism is that fluoride is suspected to inhibit salivary amylase activity.The aim of this research is to exam whether fluoride inhibits salivary amylase activity and at what concentration.Method of this research was experimental research and the design was "The posttest only control group design". The samples were taken from patients with criteria: man or woman, 13-20 years old, in fit condition, no salivary gland disorder, no caries, no gingivitis. Saliva was collected from samples fasted in the night, and asked to brush their teeth without using toothpaste. This experiment used iodium to detect the color reaction. The method also used NaF with several concentrations in saliva.The result of this experiment indicated that almost all groups have a statistically significant differences salivary amylase activity (p<0,05), except between the group without NaF and with 1 mM NaF and 2 mM NaF, betweenl mM NaF and 2 mM NaF, between 2 mM NaF dan 5 mM NaF, between 5 mM NaF and 10 mM NaF (p>0,05).Conclusion of this research found that NaF was found to inhibit the salivary amylase activity when the fluoride concentration was at and above 5 mM.

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