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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan MAHESA : Malahayati Health Student Journal
Hendsun, Hendsun
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Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : MAHESA : Malahayati Health Student Journal

 1 
Maternal Age, Gestation, and Parturition as Predictor of Uterine Inertia Incidence Wijaya, Christian; Kurniawan, Joshua; Singgih, Rendy; Firmansyah, Yohanes; Hendsun, Hendsun
MAHESA : Malahayati Health Student Journal Vol 4, No 9 (2024): Volume 4 Nomor 9 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i9.15482

Abstract

ABSTRACT Uterine inertia could cause complications in labor. Knowing the risk factors for uterine inertia is important to since the Maternal Death Rate in Indonesia is relatively high. This study was aimed to determine whether maternal age, gestation, and parturition could be predictors of uterine inertia.  This is a cross-sectional study. Data collection was done at “C” General Hospital, West Java, with all pregnant women in their third trimester of pregnancy in January to December 2019 as samples. The statistical analysis used in this study are Independent T-test, Mann Whitney, ROC Curve test, and Pearson Chi-Square with Yates Correction to see statistical associations. Significant correlation was found between the variables of age ≤ 30 years, gestation ≤ 2 pregnancies, and parturition ≤ 2 births with uterine inertia (PR = 1.331; 1.332; 1.315 times, p-value = 0.001).  Uterine inertia is affected by risk factors of age ≤ 30 years, gestation ≤ 2 pregnancies, and parturition ≤ 2 births. The results can be used to help health workers in predicting the incidence of uterine inertia so that adequate responses can be provided. Keywords: Gestation, Maternal Age, Parturition, Predictor, Uterine Inertia
Efficacy, Effectiveness, and Safety of Combination Cream (Clindamycin 3%, Tretinoin 0.05%, and Dexamethasone 0.05%) Over Their Monotherapy (Tretinoin 0.05%) in Acne Vulgaris Patients: Scaled-Up Retrospective Cohort Study Tan, Sukmawati Tansil; Firmansyah, Yohanes; Hendsun, Hendsun; Chandra, Cindy Christella
MAHESA : Malahayati Health Student Journal Vol 4, No 9 (2024): Volume 4 Nomor 9 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i9.15463

Abstract

ABSTRACT Acne vulgaris is an inflammatory disorder that impacts pilosebaceous glands, affecting many adolescents physically and psychologically. The finest acne cream comprises retinoids, antibiotics, and corticosteroids. Accuracy of acne vulgaris therapy affects the healing and prognosis. To compare the efficacy of a single topical cream containing 0.05% Tretinoin to a combination cream containing Clindamycin 3%, Tretinoin 0.05%, and Dexamethasone 0.05%. This was a retrospective cohort study that included 1027 respondents, observing the result of using 2 types of creams for treating acne: 1) a single tretinoin 0.05% cream and 2) a combination cream therapy (Clindamycin 3%, Tretinoin 0.05%, and Dexamethasone 0.05%). The evaluated parameters were mean reduction in acne lesions quantity as the main objective and other side parameters (Spot, Pore, Wrinkle, UV moisture, UV damage, Roughness, Porphyrin, Pigmentation, and Hydration) as the secondary goals. This study shows that there was a significant difference both in primary and secondary endpoints between single tretinoin 0.05% cream and combination cream therapy (Clindamycin 3%, Tretinoin 0.05%, and Dexamethasone 0.05%) with p-value <0.05 in all parameters. As for adverse events, there was no statistically significant difference locally, and no incidence was found systemically. Combination cream (Clindamycin 3%, Dexamethasone 0.05%, and Tretinoin 0.05%) might provide superior primary and secondary efficacy parameters in acne treatment than single tretinoin cream. Keywords: Acne vulgaris, Safety, Effectiveness, Tretinoin, Clindamycin, Dexamethasone
Co-Authors Buntara, Ivan Chandra, Cindy Christella Emilda, Emilda Kurniawan, Joshua Ratana, Angelica Devi Setiyati, Pinka Nurashri Singgih, Rendy Su, Ernawati Sutjipto, Fiolita Indranita Tan, Sukmawati Tansil Wijaya, Christian Yohanes Firmansyah