Titing Nurhayati
Department of Biomedical Sciences Faculty of Medicine Universitas Padjadjaran

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Comparison of Gastrocnemius Muscle Strength between Basketballs and Non-basketball Player Titing Nurhayati; Sharmili Mohanan; Marietta Shanti Prananta
Althea Medical Journal Vol 6, No 4 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v6n4.1724

Abstract

Background: Basketball is one of the best aerobic-predominant exercises and the most important muscle used in this sport is the gastrocnemius muscle. This muscle plantar flexes the ankle when the knee is extended to maintain the balance and to stabilize the body during vigorous movements. Furthermore, the gluteus, quadriceps, hamstrings, and calves may get activated when running up and down the court and jump in the air when doing basketball training. This study was conducted to compare the gastrocnemius muscle strength in basketball and non-basketball players.Methods: This analytical study was to measure the gastrocnemius muscle strength in basketball (n=16) and non-basketball (n=16) players, using hand-held dynamometer (HHD). Gender, weight, height, Body Mass Index (BMI) and maximal gastrocnemius muscle strength were recorded and compared between groups. The study was conducted from August to October 2013 in the Faculty of Medicine, Universitas Padjadjaran.Results: The maximal gastrocnemius muscle strength showed no significant differences both in basketball and non-basketball players for females and males with p-value 0.092 and 0.711, respectively.Conclusions: There is no significant difference in gastrocnemius muscle strength between basketball and non-basketball players in males as well as in females. Presumably, there are other muscles that take parts to develop leg power by doing the right weight-training exercises.
Effect of Exercise Duration on Klotho and GluN2B Gene Expressions in Hippocampus of Wistar Rats with Moderate Intensity Exercise Hanna Goenawan; Bela Ita Karina; Titing Nurhayati; Julia Windi Gunadi; Setiawan Setiawan; Ronny Lesmana
Majalah Kedokteran Bandung Vol 52, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v52n3.2026

Abstract

Exercise could delay the degeneration process by increasing Klotho, which is an endogen antioxidant. Klotho protects against oxidative damages, regulates hippocampal synaptic plasticity, and enhances GluN2B expression. This study aimed to analyze the effect of 14-day and 8-week moderate-intensity exercise on Klotho and GluN2B mRNA expressions in rat hippocampus. This study was an animal experimental study using Wistar rats that was performed from June to September 2019 at the Central Laboratory, Universitas Padjadjaran, Indonesia. Rats were divided into 4 groups: control (14-day control and 8-week control) and exercise group (14-day exercise and 8-week exercise).  The exercise groups ran at a moderate intensity (20m/min) for 30min/day, 5x/week. Hippocampus was then subjected to klotho and GluN2B gene expression analysis. The exercise groups showed a higher Klotho expression, both in 14 days (0.844±0.124 vs. 1.057±0.013) and 8 weeks (0.897±0.072 vs. 1.380±0.168) although statistically insignificant (p=0.24). No difference in GluN2B gene expression was observed between control and exercise groups on 14 days (1±0.09 vs. 1.22±0.09) and 8 weeks (1.24±0.03 vs. 1.38±0.05; p=0.11). In conclusion, 14-day and 8-week moderate-intensity exercise did not alter Klotho and GluN2B expressions in rat hippocampus. Pengaruh Durasi Olahraga terhadap Perubahan Ekspresi Gen Klotho dan GluN2B di Hipokampus Tikus Galur Wistar yang Mendapatkan Perlakuan Lari Intensitas SedangOlahraga dapat menghambat proses degenerasi saraf dengan meningkatkan salah satu antioksidan endogen, yaitu Klotho. Klotho dapat melindungi sel neuron dari kerusakan oksidatif dan meningkatkan sinaptik plasticity pada hipokampus.  Penelitian ini bertujuan untuk melihat pengaruh olahraga lari pada hewan coba pada 14 hari dan 8 minggu terhadap perubahan ekspresi gen Klotho and GluN2B di hipokampus. Penelitian ini merupakan penelitian eksperimental dilaksanakan pada bulan Juni hingga September 2019 di Laboratorium Sentral Universitas Padjadjaran. Penelitian ini menggunakan tikus jantan galur wistar. Tikus dibagi menjadi 4 kelompok perlakuan dan kontrol. Olahraga dilakukan dengan treadmill tikus, kecepatan 20m/min, 30 menit perhari selama 5 kali perminggu. Kemudian, mRNA otak digunakan untuk PCR dengan menggunakan primer klotho dan GluN2B. Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan yang bermakna (p=0.24) pada ekspresi gen Klotho pada 14 hari (0.844±0.124 vs 1.057±0.013) dan 8 minggu (0.897±0.072 vs 1.380±0.168) antara kelompok kontrol dan kelompok lari. Ekspresi gen dari GluN2B juga tidak menunjukkan perbedaan yang signifikan (p=0.11) pada 14 hari (1±0.09 vs 1.22±0.09)  dan 8 minggu (1.24±0.03 vs 1.38 ± 0.05). Simpulan, bahwa 8 minggu olahraga tidak meningkatan ekspresi Klotho dan GluN2B yang signifikan