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All Journal Farmaka Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmiah Farmasi Farmasyifa Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
Imam Adi Wicaksono
Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

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Sensitivity Assay of Resistant Escherichia coli to Fosfomycin, Kanamycin, Rifampicin, Ceftriaxone, Imipenem, and Vancomycin Tina Rostinawati Rostinawati; Rikadianan rikadianan; Imam Adi Wicaksono
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.42856

Abstract

Antibiotic resistance is a major global health problem and continues to increase, so there is a need forbetter evaluation and therapeutic advice for Urinary Tract Infection (UTI) patients. It had isolated E. colifrom clinical isolates that were resistant to antibiotics of β-lactam, the first generation of cephalosporinand fluoroquinolone. Characterization of bacterial sensitivity should be analyzed to other antibioticswith different mechanisms. Therefore, this study aims to analyze the antibiotic activity of fosfomycin,kanamycin, rifampicin, ceftriaxone, imipenem, and vancomycin against to resistant Escherichia coliclinical isolates of UTI. The sensitivity test in this study used the Kirby-Bauer disc diffusion methodand data analysis using SPSS version 24. The results revealed the diameter of inhibition zone (mm) ofantibiotics of fosfomycin, ceftriaxone, imipenem, kanamycin, rifampicin, and vancomycin respectivelyi.e. 38±1; 36.3±1.15; 35±1; 31.6±1,15; 28±1; and 26.3±0.17. Based on statistical analysis there weresignificant differences in the activity of fosfomycin, ceftriaxone, imipenem, kanamycin, rifampicin,and vancomycin.
Co-Authors Abib Latifu Fatah Afina Dwi Rahmawati Alda Anjella Lady Carina Paska Agatha Ameilia Ameilia Annisa Atusholihah AYU UTAMI DEWI Bunga Dacilia Harsanti Cecep Suhandi Dika Pramita Destiani Ersa Fadhilah Fadila Nur Annisa Ganis Fitria Fauziyyah Hanny Latifa Hazna Putri Salsabilla Ignatius James Irawan IYAN RIFKY HIDAYAT KATHERINE AUGUSTIA TJENGGAL Keri Lestari Mamay Krisman Nabilah Azka Nihlah Nadila Berliana Nicholas Sugianto Nurfianti Silvia Rahadianti Khofii Suwanditya Randy Rassi Prayoga Rano Karya Sinuraya RANO KURNIA SINURAYA Rikadianan rikadianan SILVIA PERMATA SARI Tina Rostinawati Rostinawati Umi Azizah