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All Journal ENVIAGRO Jurnal Pengabdian Kepada Masyarakat Universitas Bangka Belitung Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Biosaintifika: Journal of Biology & Biology Education Journal of Integrated Agribusiness EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi Berkala Penelitian Hayati ABDIPRAJA (Jurnal Pengabdian kepada Masyarakat)
Henny Helmi
Biology Department, Bangka Belitung University
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Biosaintifika: Journal of Biology

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The Effectiveness of Local Plants from Lom and Sawang Ethnics as Antimalarial Medicine Helmi, Henny; Afriyansyah, Budi; Ekasari, Wiwied
Biosaintifika: Journal of Biology & Biology Education Vol 8, No 2 (2016): September 2016
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v8i2.5437

Abstract

Native people or ethnic societies that live in endemic malaria islands such as in Bangka Island and Belitung Island have used many medicinal plants to cure malaria. Leaves of kesembung (Scaevola taccada (Gaertn Roxb), roots of kebentak (Wikstroemia androsaemofolia Decne), and roots of medang mencena (Dapniphyllum laurinum (Benth) are the examples. This research was aimed to investigate the present of some biochemical compound and evaluate the antimalarial activity of ethanol extract of the plants against Plasmodium falciparum 3D7 in vitro. The IC50 level was determined through visual observation under microscope over 5000 of giemsa-stained erythrocytes then analyzed by probit analysis. Results showed that kebentak root ethanol extract was effective to inhibit P. falciparum 3D7 with level 0.485 g/mL. Furthermore, the IC50 level of kesembung leaves and medang root were 44.352 g/mL and 1486.678 g/mL respectively. Phytochemical test result showed that kebentak leaf ethanol crude extract contained triterpenoid, kesembung root contained phenol and tannins; moreover, medang root contained alkaloid, saponin, and triterpenoid.How to CiteHelmi, H., Afriyansyah, B. & Ekasari, W. (2016). The Effectiveness of Local Plants from Lom and Sawang Ethnics as Antimalarial Medicine. Biosaintifika: Journal of Biology & Biology Education, 8(2), 193-200.
Co-Authors Ahmad Arsyadi Budi Afriyansyah Dea Indriani Astuti Eni Karsiningsih Idha Susanti Muhammad Soleh Rafsanjani Noptian Asmara Agung Pingkan Aditiawati Rudi Dungani Sadam Kusen Salmi Salmi Wiwied Ekasari