Haemodialysis is a treatment effort that aims to support the life of patients with end-stage renal failure which can lead to psychological experiences that can affect the well-being of life such as depression, anxiety, and stress increase the risk of losing the meaning of life. The design in this study was cross-sectional and involved 46 haemodialysis patients and the sample was selected using a purposive sampling technique. The data were tested using a non-parametric spearman rank analysis to find the correlation between self-esteem and levels of depression, anxiety, and stress. The results of the analysis show that there was a significant correlation between self-esteem and levels of depression, anxiety, and stress, which were marked with a significance value of 0.001 each. The resulting coefficient values were negative respectively -0.726, -0.016, and -0.674. Based on this value, it can be concluded that if self-esteem is low, the level of depression, anxiety, and stress will increase in haemodialysis patients.